Hematology: Leukocytes Classification
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Questions and Answers

What is the function of neutrophils?

  • Phagocytosis of infectious agents and cellular debris (correct)
  • Transport of oxygen in the blood
  • Regulation of blood pressure
  • Production of antibodies
  • Which leukocyte is most easily identified and larger than RBC?

  • Neutrophils (correct)
  • Basophils
  • Eosinophils
  • Heterophils
  • What is a common characteristic of eosinophils?

  • Bi-lobed or tri-lobed nucleus
  • Affinity for acidic stains in their granules (correct)
  • Spherical nucleus
  • Blue color cytoplasm
  • What is the main cause of toxic neutrophil production?

    <p>Inflammatory conditions accelerating maturation of cells</p> Signup and view all the answers

    What is the appearance of a hyper-segmented neutrophil?

    <p>Banded or elongated nucleus</p> Signup and view all the answers

    What does a left shift in neutrophils indicate?

    <p>Increased number of immature circulating neutrophils</p> Signup and view all the answers

    What is the function of eosinophils?

    <p>Role in allergic reactions and parasitic infections</p> Signup and view all the answers

    What does neutrophilia refer to?

    <p>Increased number of circulating neutrophils</p> Signup and view all the answers

    What is the characteristic feature of basophils?

    <p>Large, round granules in cytoplasm</p> Signup and view all the answers

    What does a right shift in neutrophils indicate?

    <p>Increase in the percent of mature or (hyper-segmented) neutrophils in the blood</p> Signup and view all the answers

    What is the characteristic feature of heterophils?

    <p>Presence of distinctive eosinophilic granules</p> Signup and view all the answers

    What is a common cause of neutropenia?

    <p>Decreased number due to neoplasia</p> Signup and view all the answers

    Study Notes

    Neutrophil Functions and Characteristics

    • Neutrophils play a crucial role in the innate immune response by combating infections, particularly bacterial pathogens.
    • They are the most abundant type of white blood cells, making up 55-70% of total leukocytes.
    • Toxic neutrophil production is often caused by severe infections, inflammation, or stress.

    Easy Identification of Leukocytes

    • Neutrophils, the most easily identifiable leukocyte, are larger than red blood cells (RBCs) and possess a multi-lobed nucleus.

    Eosinophil Characteristics and Functions

    • Eosinophils are characterized by large granules that stain orange-red with eosin dye.
    • They primarily target parasitic infections and play a role in allergic responses.

    Neutrophil Appearance and Indicators

    • Hyper-segmented neutrophils exhibit an increased number of lobes in the nucleus, with five or more lobes, often indicating megaloblastic anemia.
    • A left shift in neutrophils indicates an increased number of immature neutrophils in circulation, typically associated with acute infections or stress.

    Neutrophilia and Right Shift

    • Neutrophilia refers to an elevated neutrophil count in response to infections or inflammatory conditions.
    • A right shift in neutrophils signifies an increase in mature neutrophils and is often associated with chronic infections or steroid use.

    Basophils and Heterophils

    • Basophils are characterized by large granules that stain dark blue or purple, containing histamine and heparin, and are involved in allergic responses.
    • Heterophils, found in some species (like birds and reptiles), have a distinctive appearance, with a segmented nucleus and granules that are similar to mammalian neutrophils but differ in size and staining characteristics.

    Neutropenia Causes

    • Neutropenia, or low neutrophil count, can commonly result from conditions such as bone marrow disorders, autoimmune diseases, or the effects of chemotherapy.

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    Description

    Test your knowledge about the classification and functions of leukocytes in hematology. Learn about the different pools in which leukocytes are found and their roles in the body.

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