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Questions and Answers
What is the function of neutrophils?
Which leukocyte is most easily identified and larger than RBC?
What is a common characteristic of eosinophils?
What is the main cause of toxic neutrophil production?
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What is the appearance of a hyper-segmented neutrophil?
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What does a left shift in neutrophils indicate?
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What is the function of eosinophils?
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What does neutrophilia refer to?
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What is the characteristic feature of basophils?
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What does a right shift in neutrophils indicate?
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What is the characteristic feature of heterophils?
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What is a common cause of neutropenia?
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Study Notes
Neutrophil Functions and Characteristics
- Neutrophils play a crucial role in the innate immune response by combating infections, particularly bacterial pathogens.
- They are the most abundant type of white blood cells, making up 55-70% of total leukocytes.
- Toxic neutrophil production is often caused by severe infections, inflammation, or stress.
Easy Identification of Leukocytes
- Neutrophils, the most easily identifiable leukocyte, are larger than red blood cells (RBCs) and possess a multi-lobed nucleus.
Eosinophil Characteristics and Functions
- Eosinophils are characterized by large granules that stain orange-red with eosin dye.
- They primarily target parasitic infections and play a role in allergic responses.
Neutrophil Appearance and Indicators
- Hyper-segmented neutrophils exhibit an increased number of lobes in the nucleus, with five or more lobes, often indicating megaloblastic anemia.
- A left shift in neutrophils indicates an increased number of immature neutrophils in circulation, typically associated with acute infections or stress.
Neutrophilia and Right Shift
- Neutrophilia refers to an elevated neutrophil count in response to infections or inflammatory conditions.
- A right shift in neutrophils signifies an increase in mature neutrophils and is often associated with chronic infections or steroid use.
Basophils and Heterophils
- Basophils are characterized by large granules that stain dark blue or purple, containing histamine and heparin, and are involved in allergic responses.
- Heterophils, found in some species (like birds and reptiles), have a distinctive appearance, with a segmented nucleus and granules that are similar to mammalian neutrophils but differ in size and staining characteristics.
Neutropenia Causes
- Neutropenia, or low neutrophil count, can commonly result from conditions such as bone marrow disorders, autoimmune diseases, or the effects of chemotherapy.
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Description
Test your knowledge about the classification and functions of leukocytes in hematology. Learn about the different pools in which leukocytes are found and their roles in the body.
