18 Questions
What is the main purpose of the lumbar puncture in the diagnosis of ALL?
To collect a sample of the spinal fluid for testing
Which of the following is NOT a common symptom of acute lymphoblastic leukemia (ALL)?
Muscle cramps
What is the purpose of the molecular tests in the diagnosis of ALL?
To detect genetic abnormalities associated with ALL
What is the significance of the Philadelphia chromosome in the diagnosis of ALL?
It indicates a more aggressive form of the disease
What is the purpose of the bone marrow aspiration and biopsy in the diagnosis of ALL?
To measure the percentage of blasts in the bone marrow
Which of the following is NOT a common imaging test used in the diagnosis of ALL?
MRI
What is the most common type of acute lymphoblastic leukemia?
B-lymphoblastic leukemia/lymphoma
Which of the following is NOT a common sign or symptom of acute lymphoblastic leukemia?
Fever
What percentage of leukemia cases in children under 15 years of age is represented by acute lymphoblastic leukemia?
75%
Which of the following is a key factor affecting the prognosis of acute lymphoblastic leukemia?
Age of the patient
What is the most common cause of acute lymphoblastic leukemia?
Genetic error in an immature lymphocyte
Which of the following is a morphological subtype of acute lymphoblastic leukemia based on the French-American-British (FAB) classification?
L1, L2, or L3
Which of the following therapies is specifically mentioned as a treatment option for Philadelphia chromosome-positive (Ph+) ALL?
Targeted therapy with a tyrosine kinase inhibitor, such as imatinib
Which method of intrathecal chemotherapy is described in the figure?
Injecting drugs into the CSF in the lower part of the spinal column
According to the French-American-British (FAB) classification, which subtype of ALL has the highest frequency?
L2 (60%)
What is the key distinguishing feature among the L1, L2, and L3 subtypes of ALL mentioned in the text?
The level of nucleoli conspicuousness in the lymphoblasts
Which of the following statements about the epidemiology of ALL is true, according to the text?
ALL occurs three times more frequently in Whites than in Blacks
What is the reason provided in the text for the difference in ALL incidence between racial groups?
No reason is provided
Test your knowledge on Acute Lymphoblastic Leukemia (ALL) with this quiz. Covering the classification, prognosis factors, signs, symptoms, diagnosis, treatment, and morphological subtypes of ALL.
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