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Acute Leukemias in Hematology

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Questions and Answers

What is the minimum percentage of blasts in the bone marrow required for the diagnosis of AML according to the WHO?

15%

20% (correct)

10%

25%

What is the characteristic of chromatin in Myeloblasts?

Coarse with prominent nucleoli

Uniform and fine (correct)

Coarse

Variable

Which of the following is a characteristic of Promyelocytes?

Hypogranular

No nucleoli

Hyper-granular (correct)

No Auer rods

What is the significance of t(15;17) translocation in AML?

Good prognosis Signup and view all the answers

What is the typical age range for the onset of AML?

65 years or older Signup and view all the answers

What is the primary consequence of bone marrow failure in patients with acute leukemias?

Suppression of normal hematopoiesis, leading to anemia, neutropenia, and thrombocytopenia Signup and view all the answers

What is a common characteristic of acute leukemias in terms of cellular differentiation?

Block in cellular differentiation in the bone marrow Signup and view all the answers

Which of the following environmental exposures is NOT associated with an increased risk of hematopoietic malignancies?

Vitamin C supplementation Signup and view all the answers

What is the primary difference between acute and chronic leukemias in terms of treatment outcomes?

Acute leukemias are more aggressive, but younger patients are ultimately cured Signup and view all the answers

What is the consequence of chemotherapy-induced DNA damage in hematopoietic cells?

Therapy-related leukemias Signup and view all the answers