Podcast
Questions and Answers
What is the minimum percentage of blasts in the bone marrow required for the diagnosis of AML according to the WHO?
What is the minimum percentage of blasts in the bone marrow required for the diagnosis of AML according to the WHO?
- 15%
- 20% (correct)
- 10%
- 25%
What is the characteristic of chromatin in Myeloblasts?
What is the characteristic of chromatin in Myeloblasts?
- Coarse with prominent nucleoli
- Uniform and fine (correct)
- Coarse
- Variable
Which of the following is a characteristic of Promyelocytes?
Which of the following is a characteristic of Promyelocytes?
- Hypogranular
- No nucleoli
- Hyper-granular (correct)
- No Auer rods
What is the significance of t(15;17) translocation in AML?
What is the significance of t(15;17) translocation in AML?
What is the typical age range for the onset of AML?
What is the typical age range for the onset of AML?
What is the primary consequence of bone marrow failure in patients with acute leukemias?
What is the primary consequence of bone marrow failure in patients with acute leukemias?
What is a common characteristic of acute leukemias in terms of cellular differentiation?
What is a common characteristic of acute leukemias in terms of cellular differentiation?
Which of the following environmental exposures is NOT associated with an increased risk of hematopoietic malignancies?
Which of the following environmental exposures is NOT associated with an increased risk of hematopoietic malignancies?
What is the primary difference between acute and chronic leukemias in terms of treatment outcomes?
What is the primary difference between acute and chronic leukemias in terms of treatment outcomes?
What is the consequence of chemotherapy-induced DNA damage in hematopoietic cells?
What is the consequence of chemotherapy-induced DNA damage in hematopoietic cells?
Flashcards
AML Diagnostic Criteria (WHO)
AML Diagnostic Criteria (WHO)
20% or greater blasts in the bone marrow.
Myeloblast Chromatin
Myeloblast Chromatin
Uniform and fine.
Promyelocyte Characteristic
Promyelocyte Characteristic
Hyper-granular.
t(15;17) Significance in AML
t(15;17) Significance in AML
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Consequence of Bone Marrow Failure
Consequence of Bone Marrow Failure
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Characteristic of Acute Leukemias
Characteristic of Acute Leukemias
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Difference Between Acute & Chronic Leukemias (Treatment)
Difference Between Acute & Chronic Leukemias (Treatment)
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Chemotherapy-Induced DNA Damage Consequence
Chemotherapy-Induced DNA Damage Consequence
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