Acute Leukemias in Hematology

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What is the minimum percentage of blasts in the bone marrow required for the diagnosis of AML according to the WHO?

20%

What is the characteristic of chromatin in Myeloblasts?

Uniform and fine

Which of the following is a characteristic of Promyelocytes?

Hyper-granular

What is the significance of t(15;17) translocation in AML?

<p>Good prognosis</p> Signup and view all the answers

What is the typical age range for the onset of AML?

<p>65 years or older</p> Signup and view all the answers

What is the primary consequence of bone marrow failure in patients with acute leukemias?

<p>Suppression of normal hematopoiesis, leading to anemia, neutropenia, and thrombocytopenia</p> Signup and view all the answers

What is a common characteristic of acute leukemias in terms of cellular differentiation?

<p>Block in cellular differentiation in the bone marrow</p> Signup and view all the answers

Which of the following environmental exposures is NOT associated with an increased risk of hematopoietic malignancies?

<p>Vitamin C supplementation</p> Signup and view all the answers

What is the primary difference between acute and chronic leukemias in terms of treatment outcomes?

<p>Acute leukemias are more aggressive, but younger patients are ultimately cured</p> Signup and view all the answers

What is the consequence of chemotherapy-induced DNA damage in hematopoietic cells?

<p>Therapy-related leukemias</p> Signup and view all the answers

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