Hematology: Blood and the Circulatory System

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Questions and Answers

If a patient has a condition that prevents the fibrous pericardium from properly anchoring the heart, which of the following complications is most likely to occur?

  • Increased risk of myocardial infarction due to restricted blood flow.
  • Overstretching of the heart, leading to reduced cardiac output. (correct)
  • Inability of the heart to contract effectively due to nerve damage.
  • Accumulation of fluid in the pericardial cavity, causing cardiac tamponade.

The anterior interventricular sulcus marks the boundary between the atria and ventricles on the anterior surface of the heart.

False (B)

Explain how the unique arrangement of cardiac muscle fibers in the myocardium contributes to the heart's efficient pumping action.

The cardiac muscle fibers are arranged in bundles that swirl diagonally around the heart, allowing for a strong and coordinated contraction that efficiently ejects blood from the ventricles.

The ______ is the inner layer of the serous pericardium that adheres tightly to the surface of the heart and is also known as the epicardium.

<p>visceral layer</p> Signup and view all the answers

Match each component of the heart's structure to its primary function:

<p>Atria = Receive blood from veins Ventricles = Eject blood into arteries Fibrous Pericardium = Prevents overstretching of the heart Myocardium = Provides the pumping action of the heart</p> Signup and view all the answers

A cardiologist observes that a patient's fossa ovalis is not completely closed. What potential physiological consequence could directly result from this condition?

<p>Mixing of oxygenated and deoxygenated blood between the atria. (A)</p> Signup and view all the answers

The epicardium, due to its fibroelastic and adipose tissue content, primarily functions to generate the strong pumping actions of the heart.

<p>False (B)</p> Signup and view all the answers

Explain the clinical significance of the ligamentum arteriosum when diagnosing certain cardiovascular conditions.

<p>The ligamentum arteriosum is the remnant of the ductus arteriosus, and its presence helps in identifying the location of potential aortic injuries or malformations during imaging procedures.</p> Signup and view all the answers

The ______ is a structure resembling a dog's ear on the anterior surface of each atrium.

<p>auricle</p> Signup and view all the answers

Match the following heart valves to their respective locations and functions:

<p>Tricuspid Valve = Between the right atrium and right ventricle; prevents backflow of blood Pulmonary Valve = Between the right ventricle and pulmonary trunk; controls blood flow to the lungs Bicuspid (Mitral) Valve = Between the left atrium and left ventricle; prevents backflow of blood Aortic Valve = Between the left ventricle and aorta; controls blood flow to the systemic circulation</p> Signup and view all the answers

A patient is diagnosed with pericarditis, an inflammation of the pericardium. Which of the following is a direct consequence of this condition?

<p>Increased pressure on the heart, potentially leading to cardiac tamponade. (A)</p> Signup and view all the answers

The trabeculae carneae are smooth muscle ridges found primarily in the atria, which help in efficient blood filling.

<p>False (B)</p> Signup and view all the answers

Describe the mechanism by which the chordae tendineae and papillary muscles prevent valve prolapse during ventricular contraction.

<p>The chordae tendineae tether the valve cusps to the papillary muscles. When the ventricles contract, the papillary muscles also contract, pulling on the chordae tendineae and preventing the valve cusps from inverting into the atria.</p> Signup and view all the answers

The ______ is/are responsible for providing a smooth lining for the chambers of the heart and covering the valves.

<p>endocardium</p> Signup and view all the answers

Match each blood vessel with its primary function in relation to the heart:

<p>Superior Vena Cava = Returns deoxygenated blood from the upper body to the right atrium Inferior Vena Cava = Returns deoxygenated blood from the lower body to the right atrium Pulmonary Veins = Return oxygenated blood from the lungs to the left atrium Aorta = Distributes oxygenated blood from the left ventricle to the rest of the body</p> Signup and view all the answers

In a patient with a severely stenotic (narrowed) mitral valve, which of the following compensatory mechanisms is most likely to occur over time?

<p>Left atrial hypertrophy. (C)</p> Signup and view all the answers

The base of the heart is primarily formed by the right ventricle and is located at the inferior aspect of the heart.

<p>False (B)</p> Signup and view all the answers

Explain how the location of the heart within the mediastinum provides protection and support to the organ.

<p>The mediastinum encases the heart, offering physical protection against trauma. It also anchors the heart in place and prevents excessive movement, helping to maintain its proper functioning and position within the thoracic cavity.</p> Signup and view all the answers

The ______ is the remnant of the foramen ovale, an opening in the interatrial septum of the fetal heart.

<p>fossa ovalis</p> Signup and view all the answers

Match the following heart structures or conditions to their descriptions:

<p>Apex of the Heart = Formed by the tip of the left ventricle Coronary Sulcus = Encircles the heart, marking the boundary between atria and ventricles Trabeculae Carneae = Muscular ridges on the inner walls of the ventricles Ductus Arteriosus = A fetal blood vessel connecting the pulmonary artery to the aorta</p> Signup and view all the answers

A patient presents with a condition characterized by an abnormally thickened myocardium. How would this condition most directly affect the heart’s function?

<p>Reduced stroke volume and decreased cardiac output. (A)</p> Signup and view all the answers

The primary function of the serous pericardium is to provide structural support to the heart, preventing it from over expanding under increased blood volume.

<p>False (B)</p> Signup and view all the answers

Describe the significance of the pectinate muscles in the right atrium and explain how their absence would affect atrial function.

<p>Pectinate muscles increase the surface area of the right atrium, aiding in efficient atrial contraction and blood movement into the right ventricle. Their absence would lead to less effective contraction and reduced blood flow to the ventricle.</p> Signup and view all the answers

The ______ carry blood away from the heart, while ______ return blood to the heart.

<p>arteries, veins</p> Signup and view all the answers

Match each cardiac condition to its primary effect on heart function:

<p>Mitral Valve Stenosis = Restricts blood flow from the left atrium to the left ventricle Aortic Valve Regurgitation = Allows backflow of blood from the aorta into the left ventricle Pericardial Effusion = Accumulation of fluid in the pericardial cavity, potentially leading to cardiac tamponade Atrial Fibrillation = Irregular and rapid contraction of the atria, reducing cardiac output</p> Signup and view all the answers

If the chordae tendineae in the left ventricle are ruptured, which immediate effect would you expect to observe?

<p>Prolapse of the mitral valve into the left atrium during ventricular systole. (C)</p> Signup and view all the answers

The visceral layer of the serous pericardium directly contributes to the myocardium's ability to conduct electrical impulses.

<p>False (B)</p> Signup and view all the answers

Explain how the anatomical arrangement of the heart's surfaces (anterior, inferior, right, and left) relates to the surrounding structures.

<p>The anterior surface is related to the sternum and ribs, the inferior surface rests on the diaphragm, the right surface faces the right lung, and the left surface faces the left lung. These relationships dictate the heart's position and interaction with other organs.</p> Signup and view all the answers

The heart is located in the ______, the region between the lungs.

<p>mediastinum</p> Signup and view all the answers

Match the specific heart layers to their distinct characteristics:

<p>Epicardium = The outermost layer of the heart wall, contains blood vessels and nerves Myocardium = The thickest layer, responsible for the heart's pumping action Endocardium = The innermost layer, provides a smooth lining for the heart chambers Fibrous Pericardium = Tough, inelastic outer sac that prevents overstretching</p> Signup and view all the answers

What specific action would indicate damage to the papillary muscles?

<p>Valve prolapse (A)</p> Signup and view all the answers

The pulmonary veins carry deoxygenated blood from the lungs to the left atrium.

<p>False (B)</p> Signup and view all the answers

Describe the function of the coronary sinus and explain its importance in the context of overall blood circulation.

<p>The coronary sinus is a large vein on the posterior surface of the heart that collects deoxygenated blood from the heart muscle itself via numerous cardiac veins and delivers it to the right atrium, ensuring the heart tissue doesn't lack blood flow.</p> Signup and view all the answers

The bicuspid valve, also known as the mitral valve, is located between the ______ and the ______.

<p>left atrium, left ventricle</p> Signup and view all the answers

Match the following blood vessels with their descriptions:

<p>Aorta = The largest artery in the body; carries oxygenated blood from the left ventricle. Pulmonary Trunk = Splits into the pulmonary arteries; carries deoxygenated blood from the right ventricle to the lungs. Superior Vena Cava = Returns blood from body regions superior to the diaphragm to the right atrium. Inferior Vena Cava = Returns blood from body regions inferior to the diaphragm to the right atrium.</p> Signup and view all the answers

A patient with a long history of hypertension is found to have left ventricular hypertrophy (LVH). What is the most direct physiological consequence of LVH on heart function?

<p>Decreased end-diastolic volume due to reduced ventricular compliance. (D)</p> Signup and view all the answers

The anterior interventricular sulcus on the heart's posterior surface marks the boundary between the right and left atria.

<p>False (B)</p> Signup and view all the answers

Explain the clinical relevance of understanding the location of the heart's apex in diagnostic procedures and why it is important to correctly identify its position.

<p>Knowing the location of the apex, formed by the left ventricle, is crucial for accurate auscultation during physical exams and for guiding the placement of electrodes during electrocardiography (ECG). An incorrectly identified apex can lead to misdiagnosis or inaccurate readings.</p> Signup and view all the answers

The ______-aka the Pulmonary semilunar valve-controls the floow of blood from the right ventricle into a large artery called the ______

<p>pulmonary valve, pulmonary trunk</p> Signup and view all the answers

Flashcards

Hematology

Study of blood, blood-forming tissues, and associated disorders.

Components of the Circulatory System

The heart, blood, and blood vessels (veins and arteries).

Heart Size & Mass

12 cm (5”) Length, 9 cm (3.5”) Width, 6 cm (2.5”) Thick. Female: 250 g; Male: 300 g.

Apex of Heart

Formed by the tip of the left ventricle.

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Base of Heart

Posterior surface, formed by the atria.

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Pericardium

Membrane surrounding and protecting the heart.

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Fibrous Pericardium

Tough, inelastic layer preventing overstretching of the heart.

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Serous Pericardium

Double layer membrane; includes parietal and visceral layers.

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Parietal Layer

Outer layer of the serous pericardium, fused to the fibrous pericardium.

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Visceral Layer (Epicardium)

Inner layer of the serous pericardium, adheres to the heart surface.

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Pericardial Cavity

Space containing pericardial fluid, reduces friction.

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Epicardium

Thin, transparent outer layer, also known as the visceral layer of the serous pericardium.

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Myocardium

The middle layer responsible for the heart's pumping action.

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Endocardium

Thin inner layer that provides a smooth lining for the heart chambers and valves.

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Atria

Superior receiving chambers that receive blood from vessels.

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Auricle

Wrinkled pouch-like structure on the anterior surface of each atrium.

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Ventricles

Inferior pumping chambers that eject blood out of the heart.

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Sulci

Grooves containing coronary blood vessels and fat.

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Coronary Sulcus

Encircles the heart, marking the boundary between atria and ventricles.

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Anterior Interventricular Sulcus

Shallow groove on the anterior surface between the ventricles.

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Posterior Interventricular Sulcus

Marks the boundary between ventricles on the posterior side.

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Right Atrium

Receives blood from the superior vena cava, inferior vena cava, and coronary sinus.

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Superior Vena Cava

Returns blood from upper body.

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Inferior Vena Cava

Returns blood from lower body.

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Interatrial Septum

Partition between right and left atria.

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Fossa Ovalis

Remnant of the foramen ovale in the fetal heart.

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Tricuspid Valve

Controls blood flow from right atrium to right ventricle.

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Trabeculae Carneae

Bundles of cardiac muscle in the right ventricle.

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Chordae Tendineae

Tendon-like cords connecting tricuspid valve to papillary muscle.

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Interventricular Septum

Separates right and left ventricles.

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Pulmonary Valve

Controls blood flow from right ventricle to pulmonary trunk.

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Left Atrium

Receives blood from four pulmonary veins.

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Bicuspid (Mitral) Valve

From left Atrium to left ventricle ; has 2 cusps.

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Left Ventricle

Thickest chamber of the heart, forms the apex.

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Aortic Valve

Controls blood flow from left ventricle to ascending aorta.

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Ductus Arteriosus

Shunts blood from the pulmonary trunk into the aorta in fetal life.

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Ligamentum Arteriosum

Remnant of the ductus arteriosus after birth.

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Study Notes

  • Hematology is the study of blood, blood-forming tissues, and related disorders.
  • The circulatory system's main functions include distributing oxygen and nutrients and carrying away cellular waste and carbon dioxide.
  • It also transports water, electrolytes, hormones, and enzymes.
  • The circulatory system protects against disease, prevents hemorrhage, and regulates body temperature.

Components of the Circulatory System

  • The main components include the heart, blood, and blood vessels (veins and arteries).

Heart Size and Shape

  • Length is 12 cm (5 inches).
  • Width is 9 cm (3.5 inches) at its broadest point.
  • Thickness is 6 cm (2.5 inches).
  • Mass is around 250 g for females and 300 g for males.
  • Approximately two-thirds of the heart's mass lies to the left of the body's midline.

External Parts of the Heart

  • Apex: Formed by the tip of the left ventricle.
  • Base: The posterior surface, primarily formed by the atria (mostly the left atrium).

Distinct Surfaces of the Heart

  • Anterior
  • Inferior
  • Right
  • Left

Location of the Heart

  • The heart is located in the mediastinum.
  • The apex rests on the diaphragm.
  • The anterior surface is related to the sternum and ribs.
  • The inferior surface sits on the diaphragm.
  • The right surfaces are adjacent to the right lung base.
  • The left surfaces border the left lung base.

Pericardium

  • The pericardium is a membrane that surrounds and protects the heart.
  • It has two main parts: the fibrous pericardium and the serous pericardium.

Fibrous Pericardium

  • Composed of tough, inelastic, dense irregular connective tissue.
  • Functions include preventing overstretching, providing protection, and anchoring the heart in the mediastinum.

Serous Pericardium

  • A double layer of thinner membrane.
  • Parietal layer: The outer layer, fused to the fibrous pericardium.
  • Visceral layer (epicardium): The inner layer which adheres tightly to the heart surface and is one of the layers of the heart wall.
  • Pericardial Cavity: Reduces friction between the layers with the pericardial fluid it contains.

Layers of the Heart Wall

  • Epicardium: The thin, transparent outer layer, also called the visceral layer of the serous pericardium.
  • Myocardium: The middle layer, responsible for the heart's pumping action (95% of the heart wall), consisting of cardiac muscle fibers.
  • Endocardium: The thin inner layer of connective tissue, providing a smooth lining for the heart chambers and valves.
  • The endocardium is continuous with the endothelial lining of the large blood vessels attached to the heart.

Chambers of the Heart

Atria

  • The two superior receiving chambers.
  • Receive blood from veins returning blood to the heart.

Ventricles

  • The two inferior pumping chambers.
  • Eject blood from the heart into blood vessels.

Sulci

  • Grooves on the exterior of the heart that contain coronary blood vessels and fat.
  • Coronary sulcus: Encircles most of the heart, marking the boundary between the atria and ventricles.
  • Anterior interventricular sulcus: Marks the boundary between the right and left ventricles on the anterior surface.
  • Posterior interventricular sulcus: Marks the boundary between the ventricles on the posterior aspect of the heart.

Right Atrium

  • Forms the right border of the heart.
  • Receives blood from the superior vena cava, inferior vena cava, and coronary sinus.
  • Has a smooth posterior wall and a rough anterior wall due to pectinate muscles.
  • The interatrial septum separates the right and left atria.
  • Fossa ovalis: a remnant of the foramen ovale, a fetal opening in the interatrial septum.
  • The tricuspid valve controls blood flow from the right atrium to the right ventricle, preventing backflow.

Right Ventricle

  • Forms most of the anterior surface of the heart.
  • Contains trabeculae carneae: bundles of cardiac muscle.
  • Chordae tendineae: tendon-like cords that connect the tricuspid valve to papillary muscles.
  • The interventricular septum separates the right and left ventricles.
  • Pulmonary valve: controls the flow of blood from the right ventricle into the pulmonary trunk, which divides into the pulmonary arteries going to the lungs.

Left Atrium

  • Forms most of the base of the heart.
  • Receives blood from four pulmonary veins.
  • Features a smooth posterior and anterior wall.
  • Bicuspid or mitral valve: It controls blood flow from the left atrium to the left ventricle.

Left Ventricle

  • The thickest chamber of the heart, forming the apex.
  • Contains trabeculae carneae and chordae tendineae attached to papillary muscles.
  • Aortic valve: Controls the flow of blood from the left ventricle to the ascending aorta.

Ductus Arteriosus

  • A temporary fetal blood vessel that shunts blood from the pulmonary trunk into the aorta, bypassing the non-functioning fetal lungs.
  • After birth, it closes, leaving the ligamentum arteriosum connecting the aorta and pulmonary trunk.

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