Podcast
Questions and Answers
What is a clinical feature of a fetus with anemia?
What is a clinical feature of a fetus with anemia?
What is a potential complication of fetal anemia?
What is a potential complication of fetal anemia?
What is a characteristic of RBCs in a fetus with anemia?
What is a characteristic of RBCs in a fetus with anemia?
What is a sign of fetal anemia?
What is a sign of fetal anemia?
Signup and view all the answers
What is a feature of the bone marrow in a fetus with anemia?
What is a feature of the bone marrow in a fetus with anemia?
Signup and view all the answers
Study Notes
Iron Deficiency Anemia
- Iron storage, metabolism, and incorporation can lead to iron deficiency anemia
- Chronic inflammation can cause anemia
- Sideroblastic anemia is a type of anemia that can be hereditary or acquired
- Hereditary hemochromatosis can be homozygous or heterozygous
Laboratory Diagnosis
- Evaluation of heme synthesis is important for diagnosis
- Tests include:
- Free protoporphyrin
- Serum transferrin receptors
- Bone marrow evaluation
Anemia of Chronic Inflammation
- Causes include:
- Chronic inflammation
- Sideroblastic anemia
- Hereditary hemochromatosis
- Laboratory diagnosis involves:
- Indirect fluorescent antibody techniques
- Enzyme-linked immunosorbent assays
Hereditary Hemochromatosis
- Can cause damage to organs
- Laboratory diagnosis is crucial
- Homozygous and heterozygous forms exist
Thalassemia
- β-Thalassemia is a genetic disorder
- Silent carriers have nearly normal hemoglobin production
- Heterozygous individuals have moderate microcytic and hypochromic anemia
- homozygous β-thalassemia has severe symptoms
- Clinical features include:
- Microcytic and hypochromic anemia
- Hepatosplenomegaly
- Bone deformities
HbH Disease
- Caused by tetramers of β-globin chains
- Accumulation of β-globin chains leads to HbH formation
- Clinical features include:
- Microcytic and hypochromic anemia
- Reticulocytosis
- Hyperplasia of bone marrow
- Inclusion bodies and poikilocytosis in RBCs
Hb Bart Syndrome
- Caused by absence of β-globin production
- Hb Bart has high oxygen affinity and low delivery
- Clinical features include:
- Severe anemia
- Edema
- Ascites
- Hepatosplenomegaly
- Cardiomegaly
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
This quiz covers the different types of anemia, including iron deficiency anemia, chronic inflammation, and sideroblastic anemia. It also touches on iron metabolism and storage.
