Hematology: Anemia Examination and Classification
30 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which condition is characterized by iron loss exceeding intake and may occur when dietary intake is insufficient for the patient’s needs?

  • Megaloblastic anemia
  • Anemia of chronic disease
  • Sickle cell anemia
  • Iron deficiency anemia (correct)

What is the gold standard for diagnosing iron deficiency anemia, although it is seldom performed?

  • Bone marrow biopsy (correct)
  • Reticulocyte count
  • Complete blood count (CBC)
  • Peripheral blood smear

Which of the following is a symptom of iron deficiency anemia?

  • Glossitis (correct)
  • Jaundice
  • Photosensitivity
  • Chest pain

What does a low serum ferritin reflect in the context of iron deficiency anemia?

<p>Low body stores of iron (A)</p> Signup and view all the answers

In which group of individuals does iron deficiency anemia commonly occur due to chronic blood loss 2° to menstruation or GI bleeding?

<p>Adolescent girls and women of childbearing age (B)</p> Signup and view all the answers

Which type of RBC morphology is typically observed in iron deficiency anemia?

<p>Hypochromic and microcytic RBCs (C)</p> Signup and view all the answers

Which test is highly specific for iron deficiency anemia?

<p>Red cell distribution width (RDW) elevation (C)</p> Signup and view all the answers

What is a possible side effect of oral iron sulfate treatment?

<p>Constipation (C)</p> Signup and view all the answers

Which condition interferes with DNA synthesis, leading to a delay in blood cell maturation?

<p>Megaloblastic anemia (C)</p> Signup and view all the answers

What is the classic test for measuring the absorption of cobalamin (Vitamin B12)?

<p>Schilling test (B)</p> Signup and view all the answers

What is the interpretation of elevated methylmalonic acid (MMA) and homocysteine levels in the context of B12 deficiency?

<p>Elevated MMA and homocysteine (B)</p> Signup and view all the answers

Which disorder affects the nervous system and may present with symptoms of motor, sensory, autonomic, and/or neuropsychiatric dysfunction?

<p>Cobalamin deficiency (B)</p> Signup and view all the answers

Which type of anemia occurs when bone marrow production is unable to compensate for increased destruction of circulating blood cells?

<p>Hemolytic anemia (B)</p> Signup and view all the answers

What is the risk associated with administering IV iron dextran?

<p>Risk of anaphylaxis (A)</p> Signup and view all the answers

What is a rare cause of cobalamin deficiency?

<p>Pernicious anemia (A)</p> Signup and view all the answers

What type of RBC morphology can be seen in iron deficiency anemia?

<p>RBCs with elevated MCV (C)</p> Signup and view all the answers

Which of the following is a symptom commonly associated with iron deficiency anemia?

<p>Shortness of breath (A)</p> Signup and view all the answers

What is the most specific test for diagnosing iron deficiency anemia?

<p>Serum ferritin level (D)</p> Signup and view all the answers

Which of the following conditions can be misdiagnosed as iron deficiency anemia due to similar laboratory findings?

<p>Anemia of chronic disease (D)</p> Signup and view all the answers

What is the classic triad of symptoms associated with iron deficiency anemia?

<p>Glossitis, angular cheilitis, koilonychia (C)</p> Signup and view all the answers

Which condition interferes with DNA synthesis, leading to a delay in blood cell maturation and can be misdiagnosed as iron deficiency anemia?

<p>Vitamin B12 deficiency anemia (D)</p> Signup and view all the answers

Which of the following laboratory findings would differentiate iron deficiency anemia from anemia of chronic disease?

<p>High serum ferritin level (B)</p> Signup and view all the answers

Which of the following is a risk associated with administering IV iron dextran?

<p>Anaphylaxis (D)</p> Signup and view all the answers

What is the classic test for measuring the absorption of cobalamin (Vitamin B12)?

<p>Schilling test (B)</p> Signup and view all the answers

In the context of B12 deficiency, what does elevated methylmalonic acid (MMA) and homocysteine levels indicate?

<p>Normal B12 levels (D)</p> Signup and view all the answers

Which condition interferes with DNA synthesis, leading to a delay in blood cell maturation?

<p>Folate deficiency (B)</p> Signup and view all the answers

What type of RBC morphology can be seen in iron deficiency anemia?

<p>Microcytic and hypochromic cells (D)</p> Signup and view all the answers

What is a possible side effect of oral iron sulfate treatment?

<p>Constipation (A)</p> Signup and view all the answers

What does a low serum ferritin reflect in the context of iron deficiency anemia?

<p>Low iron stores (A)</p> Signup and view all the answers

Which type of anemia occurs when bone marrow production is unable to compensate for increased destruction of circulating blood cells?

<p><strong>Hemolytic anemia</strong> (D)</p> Signup and view all the answers

Flashcards

Iron Deficiency Anemia

A condition where iron loss exceeds intake, often due to insufficient dietary intake.

Bone Marrow Biopsy

The gold standard for diagnosing iron deficiency anemia, though rarely performed due to its invasive nature.

Glossitis

An inflammation of the tongue, a common symptom of iron deficiency anemia.

Low Serum Ferritin

Reflects low body stores of iron, often seen in iron deficiency anemia.

Signup and view all the flashcards

Adolescent Girls and Women of Childbearing Age

Commonly affected group due to chronic blood loss from periods or gastrointestinal bleeding.

Signup and view all the flashcards

Hypochromic and Microcytic RBCs

Characteristic red blood cell morphology in iron deficiency anemia.

Signup and view all the flashcards

Red Cell Distribution Width (RDW) Elevation

A highly specific test for iron deficiency anemia, indicating variability in red blood cell size.

Signup and view all the flashcards

Constipation

A potential side effect of oral iron sulfate treatment.

Signup and view all the flashcards

Megaloblastic Anemia

Interferes with DNA synthesis, causing delayed blood cell maturation.

Signup and view all the flashcards

Schilling Test

The classic test for measuring the absorption of cobalamin (Vitamin B12).

Signup and view all the flashcards

Elevated Methylmalonic Acid (MMA) and Homocysteine Levels

Elevated MMA and homocysteine levels indicate potential deficiency.

Signup and view all the flashcards

Cobalamin Deficiency

A neurological disorder related to cobalamin deficiency with diverse symptoms.

Signup and view all the flashcards

Hemolytic Anemia

A type of anemia where bone marrow cannot replace red blood cells being destroyed.

Signup and view all the flashcards

Risk of Anaphylaxis

A potential complication of intravenous iron dextran administration.

Signup and view all the flashcards

Pernicious Anemia

An uncommon cause of cobalamin deficiency characterized by autoimmune destruction of stomach cells.

Signup and view all the flashcards

RBCs with Elevated MCV

An elevated mean corpuscular volume (MCV) can be observed in iron deficiency anemia due to the presence of larger red blood cells.

Signup and view all the flashcards

Shortness of Breath

Commonly experienced by individuals with iron deficiency anemia.

Signup and view all the flashcards

Serum Ferritin Level

The most specific test for diagnosing iron deficiency anemia.

Signup and view all the flashcards

Anemia of Chronic Disease

Can have similar lab findings to iron deficiency anemia, making diagnosis difficult.

Signup and view all the flashcards

Glossitis, Angular Cheilitis, Koilonychia

Classic trio of symptoms associated with iron deficiency anemia.

Signup and view all the flashcards

Vitamin B12 Deficiency Anemia

Similar laboratory findings to iron deficiency anemia, requiring differentiation.

Signup and view all the flashcards

High Serum Ferritin Level

A high level of serum ferritin helps differentiate iron deficiency anemia from other types of anemia.

Signup and view all the flashcards

Anaphylaxis

A serious risk associated with intravenous iron dextran, requiring caution.

Signup and view all the flashcards

Schilling Test

The classic method for measuring the absorption of cobalamin (Vitamin B12).

Signup and view all the flashcards

Elevated Methylmalonic Acid (MMA) and Homocysteine Levels

Elevated levels indicate potential cobalamin deficiency, even if B12 levels appear normal.

Signup and view all the flashcards

Folate Deficiency

Interferes with DNA synthesis, leading to delayed blood cell maturation, similar to iron deficiency anemia.

Signup and view all the flashcards

Microcytic and Hypochromic Cells

Characterized by small, pale red blood cells, a typical finding in iron deficiency anemia.

Signup and view all the flashcards

Constipation

A potential side effect of oral iron sulfate treatment.

Signup and view all the flashcards

Low Serum Ferritin

Reflects low body iron stores, often seen in iron deficiency anemia.

Signup and view all the flashcards

Hemolytic Anemia

A type of anemia where the bone marrow cannot produce enough red blood cells to replace those being destroyed.

Signup and view all the flashcards

More Like This

Anemia Classification in Children
14 questions
W1-9 Principles of hematology
39 questions
Anemia Classification
18 questions
Classification of Anemia Flashcards
28 questions
Use Quizgecko on...
Browser
Browser