Hematology and Coagulation Inhibitors
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Questions and Answers

What is the primary use of heparin in medical studies?

  • Cancer treatment
  • Coagulation studies
  • Hematological studies (correct)
  • Cardiac research

What is the natural source of heparin?

  • Liver
  • Blood (correct)
  • Pancreas
  • Kidney

What is the effect of heparin on prothrombin?

  • It inhibits its conversion to thrombin (correct)
  • It accelerates its conversion to thrombin
  • It converts thrombin to prothrombin
  • It has no effect on prothrombin

What is CBC an abbreviation for?

<p>Complete Blood Count (A)</p> Signup and view all the answers

What is the primary function of thrombin in the blood?

<p>To facilitate blood clotting (B)</p> Signup and view all the answers

Where is the enzyme Alanine Transferase primarily found?

<p>Liver and kidney (D)</p> Signup and view all the answers

Which of the following enzymes is not often tested alongside ALT?

<p>Pepsin (D)</p> Signup and view all the answers

What is the purpose of testing ALT and other liver enzymes?

<p>To diagnose and monitor liver diseases (A)</p> Signup and view all the answers

What is the name of the enzyme often tested alongside ALT?

<p>Aspartate Transaminase (B)</p> Signup and view all the answers

What is bilirubin?

<p>A type of pigment (B)</p> Signup and view all the answers

What type of sample is ideal for blood glucose testing?

<p>Serum or plasma (C)</p> Signup and view all the answers

What is the primary concern when handling blood glucose specimens?

<p>Preventing bacterial contamination (A)</p> Signup and view all the answers

How long is glucose concentration stable in serum at 25°C?

<p>8 hours (B)</p> Signup and view all the answers

At what temperature can glucose concentration remain stable for 72 hours?

<p>4°C (C)</p> Signup and view all the answers

What happens to glucose concentration in hemolyzed serum?

<p>It is unaffected (D)</p> Signup and view all the answers

What is one of the factors that affect PPG?

<p>The amount and type of food (D)</p> Signup and view all the answers

What is the name of the hormone that raises blood glucose levels?

<p>Glucagon (C)</p> Signup and view all the answers

What is the definition of Fasting Blood Glucose (FB)?

<p>The level of blood glucose after 6-8 hours of fasting (A)</p> Signup and view all the answers

What is the opposite of glucagon in terms of its effect on blood glucose levels?

<p>Insulin (B)</p> Signup and view all the answers

What is the primary factor that affects blood glucose levels?

<p>The amount and type of food (D)</p> Signup and view all the answers

What type of tubes are used to obtain serum blood?

<p>Yellow-top tubes (C)</p> Signup and view all the answers

What is the main purpose of using a yellow-top tube?

<p>To collect serum blood (B)</p> Signup and view all the answers

What does PPG stand for in medical terminology?

<p>Post Prandial Glucose (A)</p> Signup and view all the answers

What is PPG a measure of?

<p>Plasma glucose concentration after eating (A)</p> Signup and view all the answers

What type of glucose level is PPG NOT a measure of?

<p>Fasting glucose level (C)</p> Signup and view all the answers

Study Notes

Blood Collection Tubes with Anticoagulants

  • Mainly used for hematological studies, such as Complete Blood Count (CBC)
  • Example of anticoagulant: EDTA
  • Heparin: naturally present in blood, inhibits conversion of prothrombin to thrombin

Blood Collection Tubes without Anticoagulants

  • Used to obtain serum blood
  • Example: yellow-top tube

Blood Glucose Levels

  • Post Prandial Glucose (PPG) Level: plasma glucose concentration after eating
  • Factors affecting PPG:
    • Amount and type of food
    • Insulin and glucagon secretion
  • Fasting Blood Glucose (FB) Level: blood glucose level after 6-8 hours of fasting

Collecting and Handling Specimens for Blood Glucose Test

  • Use serum or plasma free of hemolysis
  • Glucose concentration stable in separate, non-hemolyzed serum for:
    • Up to 8 hours at 25°C
    • Up to 72 hours at 4°C, if kept free of bacterial contamination

Alanine Transferase (ALT)

  • Enzyme found primarily in liver and kidney
  • Often tested alongside AST, GGT, ALP, and bilirubin to diagnose and monitor liver diseases

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Description

This quiz covers the basics of hematological studies, including CBC, and the role of heparin in inhibiting the conversion of prothrombin to thrombin.

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