Hematology Analyzer Quality Control

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16 Questions

What is the ideal scenario in terms of accuracy and precision?

Accurate and precise

What is the typical cause of a trend in the Levey-Jennings curve?

Drift of the instrument

Why is quality control in hematology important?

To ensure consistent reliability of sample results

What can cause a shift in the measurement values?

Environmental changes

What is the primary goal of quality control in hematology?

To control accuracy and precision of measurements

What is characterized by a sudden shift of the values?

Shift

What is the term for varying measurements around the correct target value?

Imprecision

What do hematology controls typically resemble?

Patient samples

How many levels of hematology controls are usually provided by instrument manufacturers?

Two or three

What should be verified in case of a shift?

Part change on the instrument

What is the purpose of internal quality control?

To detect errors and ensure long-term quality

What can contribute to a trend in the Levey-Jennings curve?

All of the above

What is precision in the context of hematology controls?

The ability to achieve the same result over and over again

What is the purpose of knowing the root cause of each situation?

To take the proper corrective action

What is the purpose of daily measurement of quality control samples?

To ensure patient result accuracy

What is accuracy in the context of hematology controls?

The ability to achieve the right result

Study Notes

Hematology Controls and Quality Control

  • Hematology controls help assess the precision of hematology analyzers, ensuring valid patient results and meeting accreditation requirements.
  • Daily measurement of quality control samples is obligatory for intra-instrument quality control.
  • Controls with assayed values for three-part and five-part differential analysis, as well as erythrocyte sedimentation controls, are available.

Importance of Quality Control in Hematology

  • Quality control should be performed routinely to ensure the consistent reliability of sample results.
  • Each laboratory should establish their own QC program complying with accreditation guidelines.
  • Four main purposes of internal QC:
    • Monitoring of the analytical process
    • Detection of errors due to system failure, adverse environmental conditions, or operator performance
    • Monitoring of long-term test performance
    • Providing a proof of adequate long-term quality level and complying with regulatory requirements

Accuracy and Precision in Hematology Controls

  • Accuracy refers to the ability to achieve the right result, while precision refers to the ability to achieve the same result over and over again.
  • Four scenarios of accuracy and precision:
    • Accurate and precise values (ideal scenario)
    • Not accurate and precise values (trend, often caused by instrument drift or other factors)
    • Not accurate but precise values (shift, often caused by changes in reagents or environment)
    • Accurate but not precise values (imprecision, often caused by various conditions)

Assessing the precision of hematology analyzers to ensure valid patient results and meet accreditation requirements. This includes daily measurement of quality control samples and using controls with assayed values for differential analysis.

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