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Questions and Answers
What is the ideal scenario in terms of accuracy and precision?
What is the ideal scenario in terms of accuracy and precision?
What is the typical cause of a trend in the Levey-Jennings curve?
What is the typical cause of a trend in the Levey-Jennings curve?
Why is quality control in hematology important?
Why is quality control in hematology important?
What can cause a shift in the measurement values?
What can cause a shift in the measurement values?
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What is the primary goal of quality control in hematology?
What is the primary goal of quality control in hematology?
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What is characterized by a sudden shift of the values?
What is characterized by a sudden shift of the values?
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What is the term for varying measurements around the correct target value?
What is the term for varying measurements around the correct target value?
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What do hematology controls typically resemble?
What do hematology controls typically resemble?
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How many levels of hematology controls are usually provided by instrument manufacturers?
How many levels of hematology controls are usually provided by instrument manufacturers?
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What should be verified in case of a shift?
What should be verified in case of a shift?
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What is the purpose of internal quality control?
What is the purpose of internal quality control?
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What can contribute to a trend in the Levey-Jennings curve?
What can contribute to a trend in the Levey-Jennings curve?
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What is precision in the context of hematology controls?
What is precision in the context of hematology controls?
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What is the purpose of knowing the root cause of each situation?
What is the purpose of knowing the root cause of each situation?
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What is the purpose of daily measurement of quality control samples?
What is the purpose of daily measurement of quality control samples?
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What is accuracy in the context of hematology controls?
What is accuracy in the context of hematology controls?
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Study Notes
Hematology Controls and Quality Control
- Hematology controls help assess the precision of hematology analyzers, ensuring valid patient results and meeting accreditation requirements.
- Daily measurement of quality control samples is obligatory for intra-instrument quality control.
- Controls with assayed values for three-part and five-part differential analysis, as well as erythrocyte sedimentation controls, are available.
Importance of Quality Control in Hematology
- Quality control should be performed routinely to ensure the consistent reliability of sample results.
- Each laboratory should establish their own QC program complying with accreditation guidelines.
- Four main purposes of internal QC:
- Monitoring of the analytical process
- Detection of errors due to system failure, adverse environmental conditions, or operator performance
- Monitoring of long-term test performance
- Providing a proof of adequate long-term quality level and complying with regulatory requirements
Accuracy and Precision in Hematology Controls
- Accuracy refers to the ability to achieve the right result, while precision refers to the ability to achieve the same result over and over again.
- Four scenarios of accuracy and precision:
- Accurate and precise values (ideal scenario)
- Not accurate and precise values (trend, often caused by instrument drift or other factors)
- Not accurate but precise values (shift, often caused by changes in reagents or environment)
- Accurate but not precise values (imprecision, often caused by various conditions)
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Description
Assessing the precision of hematology analyzers to ensure valid patient results and meet accreditation requirements. This includes daily measurement of quality control samples and using controls with assayed values for differential analysis.