Hematology Analyzers

Hematology Analyzers and Blood Count

• Early hematology analyzers primarily relied on the principle of light absorption and electrical resistance to analyze blood samples.
• A complete blood count (CBC) serves to evaluate overall health, diagnose conditions, and monitor medical treatments by measuring various blood components.
• Parameters not typically included in a CBC are tests for specific proteins or markers like electrolytes and hormones.
• RBC stands for Red Blood Cells, which are a critical component measured in a CBC, indicating oxygen-carrying capacity.

Modern Techniques and Recombinant DNA

• Modern hematology analyzers utilize advanced techniques such as flow cytometry, which assesses cells based on their size and granularity through laser detection.
• Recombinant DNA molecules are characterized by the combination of genetic material from different sources, allowing the study and manipulation of genes.
• The term "chimeric DNA" refers to recombinant DNA molecules made from material originating from two different species.
• Key characteristics of rDNA technology include the ability to insert, delete, or modify genetic sequences, enabling applications in medicine and research.

DNA Composition and Sequences

• DNA molecules from different organisms share a common chemical structure, consisting of nucleotides, which include deoxyribose sugar, phosphate groups, and nitrogenous bases.
• An example of a possible combination of DNA sequences in recombinant DNA molecules includes the fusion of an antibiotic resistance gene from a bacterium with a promoter sequence from a virus, creating a hybrid gene for study or therapeutic purposes.