Heavy Metal Toxicity Overview
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Heavy Metal Toxicity Overview

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@WellRegardedNashville

Questions and Answers

What is the primary mechanism of acute arsenic toxicity?

Decreased production of ATP

Which of the following is NOT a common gastrointestinal symptom of acute arsenic toxicity?

Constipation

Which of the following is a common cardiovascular effect of acute arsenic toxicity?

Prolonged QT interval

Which of the following is a common complication of chronic arsenic toxicity?

<p>Peripheral sensory neuropathy</p> Signup and view all the answers

Which of the following is a characteristic skin finding in chronic arsenic toxicity?

<p>Hyperpigmentation and hyperkeratosis</p> Signup and view all the answers

What is the first-line chelation therapy for acute arsenic toxicity?

<p>Dimercaprol (BAL)</p> Signup and view all the answers

Which of the following is NOT a primary use of cadmium?

<p>Automotive fuel additives</p> Signup and view all the answers

Which route of exposure is considered the primary pathway for cadmium absorption?

<p>Inhalation of vapor and fumes</p> Signup and view all the answers

Which of the following is NOT a manifestation of chronic cadmium nephrotoxicity?

<p>Hypercalciuria</p> Signup and view all the answers

Which organ serves as the primary reservoir for cadmium accumulation in the body?

<p>Kidneys</p> Signup and view all the answers

What is the approximate half-life of cadmium in the body?

<p>7-30 years</p> Signup and view all the answers

Which of the following is NOT a clinical manifestation of acute cadmium toxicity?

<p>Peripheral neuropathy</p> Signup and view all the answers

What is the most toxic form of arsenic?

<p>Arsine gas</p> Signup and view all the answers

Which of the following is NOT a use of inorganic arsenic compounds?

<p>Fuel additives</p> Signup and view all the answers

Which condition is associated with increased arsenic toxicity due to impaired metabolism?

<p>Alcoholism</p> Signup and view all the answers

What is the primary mechanism by which the body eliminates arsenic?

<p>Renal excretion</p> Signup and view all the answers

What is the primary mechanism by which arsenic causes toxicity?

<p>Inhibition of pyruvate dehydrogenase, impairing gluconeogenesis</p> Signup and view all the answers

Which route of exposure is associated with the highest absorption of arsenic?

<p>Pulmonary (inhalation)</p> Signup and view all the answers

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