Microbioloy Midterm 2
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What are healthcare-associated infections (HAIs) and why are they significant in hospitals?

HAIs are infections acquired while receiving treatment in a healthcare facility; they are significant because they affect 1 in 25 hospital patients and can lead to severe health complications or death.

Define a compromised host and explain its relevance to healthcare-associated infections.

A compromised host is an individual with impaired resistance to infection due to disease, therapy, or burns, making them more susceptible to HAIs.

List three primary risk factors for the occurrence of healthcare-associated infections.

The three primary risk factors are microorganisms in the hospital environment, the weakened status of the host, and the chain of transmission within the hospital.

How do healthcare-associated infections typically arise from their risk factors?

<p>HAIs typically arise from a combination of the three risk factors; usually, one risk factor alone is not sufficient to cause the infection.</p> Signup and view all the answers

What significant statistics underscore the impact of healthcare-associated infections in the U.S.?

<p>In the U.S., approximately 2 million patients are infected by HAIs each year, resulting in about 20,000 deaths.</p> Signup and view all the answers

What role do photoautotrophs play in the carbon cycle?

<p>They fix CO2 into organic matter using energy from sunlight.</p> Signup and view all the answers

How do chemoheterotrophs contribute to the carbon cycle?

<p>They use organic matter for energy, releasing CO2 during respiration.</p> Signup and view all the answers

What is the impact of excessive CO2 on the carbon cycle?

<p>It unbalances the carbon cycle and contributes to global warming.</p> Signup and view all the answers

What is the primary function of decomposers in the carbon cycle?

<p>Decomposers oxidize organic compounds from dead plants and animals.</p> Signup and view all the answers

Why is nitrogen fixation important in the nitrogen cycle?

<p>It converts nitrogen gas (N2) into ammonia (NH3), making nitrogen usable by plants.</p> Signup and view all the answers

What is 'ammonification' in the nitrogen cycle?

<p>It is the release of ammonia by bacteria and fungi from decomposed organic matter.</p> Signup and view all the answers

How do microbial processes impact nitrogen availability in the ecosystem?

<p>They decompose organic matter and convert it into forms like ammonia and ammonium.</p> Signup and view all the answers

What inhibits most organisms from directly using atmospheric nitrogen (N2)?

<p>N2 must be fixed into organic compounds by specialized microorganisms.</p> Signup and view all the answers

What are aseptic packages made of that cannot tolerate heat?

<p>Aseptic packages are made of materials like paper and plastic.</p> Signup and view all the answers

How are metal containers sterilized in aseptic packaging?

<p>Metal containers are sterilized with super-heated steam or high-energy electron beams.</p> Signup and view all the answers

What is the unit of measurement for ionizing radiation?

<p>Ionizing radiation is measured in Grays.</p> Signup and view all the answers

What is the low dose of ionizing radiation typically used to sterilize spices?

<p>A low dose of ionizing radiation typically used to sterilize spices is 10 kGy.</p> Signup and view all the answers

What is the range of radiation dose needed to kill non-endospore-forming bacteria?

<p>The dose needed is between 0.5 to 10 kGy.</p> Signup and view all the answers

What type of radiation sterilizes by causing water molecules to oscillate?

<p>Microwave radiation sterilizes by causing water molecules to oscillate.</p> Signup and view all the answers

Which microorganisms are notably not affected by ionizing radiation?

<p>Prions are not affected by ionizing radiation.</p> Signup and view all the answers

What is the radiation dose range necessary to kill bacterial endospores?

<p>The radiation dose needed to kill bacterial endospores is between 10 to 50 kGy.</p> Signup and view all the answers

What is the most important method for preventing nosocomial infections?

<p>Handwashing is the most important method for preventing nosocomial infections.</p> Signup and view all the answers

What is a compromised host?

<p>A compromised host is an individual with a weakened immune system, making them more susceptible to infections.</p> Signup and view all the answers

How are nosocomial infections primarily transmitted?

<p>Nosocomial infections are primarily transmitted through direct contact with contaminated surfaces or healthcare workers.</p> Signup and view all the answers

Name one example of a factor contributing to the emergence of infectious diseases.

<p>Genetic recombination is one factor contributing to emerging infectious diseases.</p> Signup and view all the answers

What role does an infection control committee play in a hospital?

<p>An infection control committee audits hospital practices to reduce the rate of healthcare-associated infections (HAIs).</p> Signup and view all the answers

Give an example of an antibiotic-resistant strain that has emerged.

<p>The W strain of Mycobacterium tuberculosis is an example of an antibiotic-resistant strain.</p> Signup and view all the answers

What is a major reason behind the reemergence of old diseases?

<p>The reemergence of old diseases can be attributed to factors like loss of immunity in a population or changes in the environment.</p> Signup and view all the answers

What kind of diseases are considered emerging infectious diseases?

<p>Emerging infectious diseases are those that are new, increasing in incidence, or have the potential to increase.</p> Signup and view all the answers

Why is it necessary to specify the term fecal coliform in water quality testing?

<p>Fecal coliform specifically indicates contamination from fecal matter, which poses a higher health risk than other types of coliform bacteria.</p> Signup and view all the answers

How do flocculants such as alum aid in water purification?

<p>Flocculants like alum bind with colloidal impurities to form larger aggregates, which then settle out of the water during sedimentation.</p> Signup and view all the answers

What is the primary goal of primary sewage treatment?

<p>The primary goal is to remove solids from sewage, allowing for sedimentation and collection of sludge.</p> Signup and view all the answers

What is the role of aerobic bacteria in secondary sewage treatment?

<p>Aerobic bacteria metabolize organic matter in wastewater, significantly reducing the BOD.</p> Signup and view all the answers

How does chlorination contribute to sewage treatment?

<p>Chlorination disinfects sewage by eliminating harmful pathogens before it is released into the environment.</p> Signup and view all the answers

What is the purpose of anaerobic digesters in sludge treatment?

<p>Anaerobic digesters facilitate the degradation of organic solids by anaerobic bacteria, producing methane and carbon dioxide.</p> Signup and view all the answers

Describe the function of septic tanks in sewage treatment.

<p>Septic tanks provide primary treatment by allowing solids to settle and be decomposed by soil microorganisms.</p> Signup and view all the answers

What happens in oxidation ponds during sewage treatment?

<p>In oxidation ponds, sludge settles first, and then effluent is pumped to shallow ponds where algae produce oxygen for decomposition.</p> Signup and view all the answers

What constitutes tertiary sewage treatment?

<p>Tertiary sewage treatment involves additional removal of remaining BOD, nitrogen, and phosphorus through advanced physical and chemical methods.</p> Signup and view all the answers

What is the main difference in effectiveness between primary and secondary sewage treatment?

<p>Primary treatment removes 25-35% of BOD, while secondary treatment can remove 75-95% due to the action of aerobic microorganisms.</p> Signup and view all the answers

What is the purpose of the Morbidity and Mortality Weekly Report (MMWR)?

<p>The MMWR publishes data on morbidity and mortality associated with notifiable diseases in the United States.</p> Signup and view all the answers

How is the morbidity rate calculated?

<p>The morbidity rate is calculated by determining the number of affected individuals in relation to the total population over a specified time period.</p> Signup and view all the answers

What distinguishes notifiable infectious diseases?

<p>Notifiable infectious diseases are those that physicians are legally required to report when they occur.</p> Signup and view all the answers

Define mortality rate in the context of infectious diseases.

<p>The mortality rate refers to the number of deaths caused by a disease in relation to the population during a specific time frame.</p> Signup and view all the answers

Provide an example of a notifiable disease.

<p>HIV Infection is an example of a notifiable disease.</p> Signup and view all the answers

What role does the CDC play in public health regarding epidemiological information?

<p>The CDC collects and analyzes epidemiological data to inform public health policies and responses.</p> Signup and view all the answers

What is the significance of having national notifications for diseases like tuberculosis?

<p>National notifications for diseases like tuberculosis help in early detection and implementation of control measures.</p> Signup and view all the answers

Why is it important to differentiate between morbidity and mortality in reports?

<p>Differentiating between morbidity and mortality is important to understand the impact of a disease on life quality and survival.</p> Signup and view all the answers

Name one preventive measure that can help reduce morbidity and mortality rates of infectious diseases.

<p>Vaccination is a preventive measure that can reduce both morbidity and mortality rates.</p> Signup and view all the answers

What type of information does the CDC compile in relation to hemolytic uremic syndrome?

<p>The CDC compiles epidemiological data regarding the incidence and impact of hemolytic uremic syndrome.</p> Signup and view all the answers

Flashcards

Carbon fixation

The process by which CO2 is converted into organic matter using energy from sunlight.

Chemoheterotrophs

Organisms that use organic matter for energy, releasing CO2 and energy through respiration.

Decomposers

Organisms that break down dead organic matter, releasing CO2 and nutrients back into the environment.

Nitrogen fixation

The process by which nitrogen gas in the atmosphere is converted into ammonia, making nitrogen available to plants.

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Nitrogenase

The enzyme used by nitrogen-fixing bacteria to convert nitrogen gas to ammonia.

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Deamination

The process by which proteins are broken down into amino acids, releasing ammonia.

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Ammonification

The release of ammonia from the breakdown of organic matter.

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Ammonium formation

The conversion of ammonia into ammonium ions (NH4+), which are then available to plants.

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What are healthcare-associated infections (HAIs)?

Infections acquired while receiving treatment in a healthcare facility. Also known as nosocomial infections.

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What is a compromised host?

An individual whose resistance to infection is weakened by disease, therapy, or burns. They are more susceptible to HAIs.

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How can diseases be transmitted in hospitals?

The spread of microorganisms within a healthcare environment. Examples include direct contact, airborne transmission, contaminated surfaces, and medical equipment.

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What are the three risk factors for HAIs?

Microorganisms present in the hospital environment, weakened host status, and the chain of transmission.

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How can HAIs be prevented?

Preventing HAIs involves proper hand hygiene, disinfection, isolation of infected patients, and following standard precautions.

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Nosocomial Infections

Infections acquired in a healthcare setting, like hospitals or clinics.

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Compromised Host

A person with weakened defenses, making them more susceptible to infections.

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Contact Transmission

The primary method of spreading nosocomial infections, often involving contact with contaminated surfaces or healthcare personnel.

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Infection Control

Practices that prevent the spread of infections, like handwashing, disinfection, and using disposable materials.

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Infection Control Committee

A team dedicated to monitoring and reducing infections within a healthcare facility.

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Emerging Infectious Diseases

New or re-emerging diseases that are causing increased concern.

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Genetic Recombination

The reason for the emergence of many infectious diseases. It can lead to antibiotic resistance and new strains.

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Epidemiology

The science of studying the distribution and determinants of health and diseases in specific populations.

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Aseptic Packaging

A type of packaging where the materials themselves are not heat-resistant and therefore cannot undergo conventional heat sterilization. Instead, the materials are sterilized beforehand (e.g., using hydrogen peroxide or UV light for paper/plastic, steam or electron beams for metal). The food is also sterilized before filling, and the package is not sterilized after sealing.

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Ionizing Radiation

A process that uses high-energy radiation to kill microorganisms in food products. This method uses radiation that displaces electrons from atoms, creating ions. Commonly used forms are x-rays and gamma rays.

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Gray (Gy)

The unit of measurement for absorbed radiation energy. One Gray signifies the absorption of one Joule of radiation energy per kilogram of matter.

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Low Dose Ionizing Radiation

A relatively low dose of ionizing radiation (10 kGy) used to significantly reduce or eliminate harmful bacteria in spices, extending their shelf life.

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Microwave Radiation

A specific form of electromagnetic radiation used for sterilization. While it does not ionize directly, it causes water molecules to vibrate intensely, generating heat that kills microbes.

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Table 28.1

A table summarizing the approximate dose of ionizing radiation required to kill various organisms. This table showcases that different organisms have different sensitivities to radiation.

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Prions

Prions are infectious agents that cause serious brain diseases, such as Creutzfeldt-Jakob disease. They are highly resistant to conventional sterilization methods and are not affected by even high doses of ionizing radiation.

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Radiation Preservation

The process of using ionizing radiation to reduce or eliminate microbial contamination in food, extending shelf life and enhancing safety.

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Primary Sewage Treatment

The process of removing solid particles from wastewater through sedimentation.

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Biochemical Oxygen Demand (BOD)

A measure of the amount of biodegradable organic matter in water. It reflects the oxygen needed by bacteria to decompose this matter.

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Activated Sludge System

The process of using microbes (mostly Zoogloea) in a tank with air pumped in to further remove organic matter from wastewater.

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Trickling Filters

A method of secondary wastewater treatment where sewage is sprayed over a bed of rocks or plastic, fostering a biofilm of aerobic microbes for further decomposition.

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Rotating Biological Contactor

A secondary sewage treatment method that uses rotating disks to aerate wastewater and grow a biofilm of aerobic microbes.

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Disinfection and Release

The final step in typical sewage treatment where chlorination is used to kill remaining harmful microbes before releasing the treated water.

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Sludge Digestion

Breaking down the solid sludge removed during primary treatment using anaerobic bacteria. These bacteria create methane and carbon dioxide as byproducts.

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Septic Tank

A device used for primary sewage treatment in areas with low population density. It uses a tank to hold and partially treat sewage.

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Oxidation Ponds

A series of shallow ponds used for secondary wastewater treatment. The first pond settles sludge, while the second pond promotes the growth of algae, which produces oxygen for aerobic decomposition.

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Tertiary Sewage Treatment

A final stage in sewage treatment, after primary and secondary stages, that aims to remove nearly all remaining BOD, nitrogen, and phosphorus from treated water.

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What does the CDC do?

The collection and analysis of disease data in the US.

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What is the MMWR?

A weekly report published by the CDC that tracks the incidence and mortality of notifiable diseases in the US.

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What is a notifiable infectious disease?

A disease that physicians are legally obligated to report to public health authorities.

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What is morbidity rate?

The number of cases of a specific disease in a population within a specific time.

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What is mortality rate?

The number of deaths from a specific disease in a population within a specific time.

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What is Botulism?

A bacterial infection that can cause severe food poisoning.

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What is Chlamydia?

A sexually transmitted infection caused by a bacteria.

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What is Influenza?

A viral infection that can cause severe respiratory illness.

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What is Poliomyelitis?

A serious viral infection that can cause paralysis.

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What is Syphilis?

A bacterial infection that can cause a severe rash.

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Study Notes

Overview

  • The provided images are slides from a microbiology lecture. They cover various topics including environmental microbiology, referencing, scientific paper dissection, microbial diversity, and several different biogeochemical cycles, including the carbon, nitrogen, and sulfur cycles. Also included are discussions about wastewater/sewage treatment, food microbiology, and the isolation of novel metabolites.

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Description

This quiz covers the fundamental concepts of healthcare-associated infections (HAIs), their significance in hospital settings, and the various risk factors associated with their occurrence. Additionally, it explores the role of microorganisms and processes in the carbon and nitrogen cycles, touching on topics such as decomposers and nitrogen fixation. Test your knowledge on these important health and ecological topics!

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