MOD 7 Biology
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Questions and Answers

Which definition best describes health?

  • A state of complete physical, mental and social well-being. (correct)
  • The ability to perform vital functions normally.
  • A combination of lifestyle choices and medical treatments.
  • The absence of disease or infirmity.

What type of disease cannot be transmitted from one person to another?

  • Genetically inherited diseases (correct)
  • Vector-borne diseases
  • Infectious diseases
  • Zoonotic diseases

Which of the following is a mode of transmission for infectious diseases?

  • Environmental exposure
  • Genetic predisposition
  • Nutritional deficiency
  • Indirect contact (correct)

Which term refers to an organism that feeds on or in another living organism?

<p>Parasite (B)</p> Signup and view all the answers

What best describes an ectoparasite?

<p>An organism living outside the body of its host. (A)</p> Signup and view all the answers

What characterizes non-communicable diseases (NCDs)?

<p>They cannot be transmitted between individuals. (C)</p> Signup and view all the answers

Which of the following is an example of vector transmission?

<p>A mosquito biting an infected individual and then biting another person. (D)</p> Signup and view all the answers

Which statement about infectious diseases is accurate?

<p>They can be caused by microorganisms, macroorganisms, and non-cellular pathogens. (D)</p> Signup and view all the answers

What is one primary method by which Ebola is transmitted?

<p>Indirect contact through contaminated objects (D)</p> Signup and view all the answers

Which of the following is a factor that contributed to the Ebola epidemic in West Africa?

<p>Poor public health infrastructure (D)</p> Signup and view all the answers

In the investigation method for microbial testing, what is the purpose of using a control agar plate?

<p>To compare against contaminated samples (D)</p> Signup and view all the answers

Which portals of entry are common for infectious agents?

<p>Mucous membranes and respiratory system (A)</p> Signup and view all the answers

What is a key precaution when conducting microbial testing?

<p>Wear personal protective equipment (PPE) (C)</p> Signup and view all the answers

Which sampling procedure is NOT used in investigating the presence of microbes in water?

<p>Incubating samples at -20 degrees (B)</p> Signup and view all the answers

What defines the 'chain of infection'?

<p>The sequence of events leading from pathogen to susceptible host (D)</p> Signup and view all the answers

Which of the following is an example of direct contact transmission?

<p>Shaking hands with an infected individual (B)</p> Signup and view all the answers

Which description best fits the method of indirect contact transmission?

<p>Transmission occurring through contaminated surfaces (B)</p> Signup and view all the answers

What is the role of a susceptible host in the context of infectious diseases?

<p>To be more vulnerable due to certain traits (D)</p> Signup and view all the answers

What is a defining characteristic of pathogens?

<p>They can invade the body and reproduce only if conditions are favorable. (C)</p> Signup and view all the answers

Which of the following describes virulence in pathogens?

<p>The degree of damage a pathogen can cause its host. (B)</p> Signup and view all the answers

What distinguishes prion diseases from other infectious diseases?

<p>They are caused by improperly folded proteins. (B)</p> Signup and view all the answers

Which of the following diseases is classified as a prion disease?

<p>Bovine spongiform encephalopathy (C)</p> Signup and view all the answers

Which type of pathogens are unable to reproduce independently?

<p>Viruses (D)</p> Signup and view all the answers

What structural feature is common to all bacteria?

<p>Cell membrane (D)</p> Signup and view all the answers

What is the primary method by which bacteria reproduce?

<p>Binary fission (B)</p> Signup and view all the answers

What role do antibiotics play in infectious diseases?

<p>They kill or inhibit bacterial growth. (A)</p> Signup and view all the answers

What is a typical characteristic of viruses?

<p>They can have either DNA or RNA as their genetic material. (D)</p> Signup and view all the answers

Which term best describes the organisms that harbor and support pathogens?

<p>Hosts (D)</p> Signup and view all the answers

What effect does bacterial infection have on the immune system?

<p>It increases local blood flow and immune cell activity. (D)</p> Signup and view all the answers

Which type of pathogen can infect a wide variety of hosts including animals, plants, and bacteria?

<p>Viruses (C)</p> Signup and view all the answers

What is one typical symptom of prion diseases?

<p>Dementia (D)</p> Signup and view all the answers

How are pathogens commonly transmitted from the environment to hosts?

<p>Through vectors such as insects. (A)</p> Signup and view all the answers

What role do antibiotics play in treating bacterial infections?

<p>They prevent bacteria from multiplying and kill them. (D)</p> Signup and view all the answers

Which component of fungal cell walls is different from plant cell walls?

<p>Chitin (D)</p> Signup and view all the answers

What is a common method of transmission for tinea among individuals?

<p>In communal showers (A)</p> Signup and view all the answers

Which of the following is a pathogenic protozoa that causes malaria?

<p>Plasmodium (D)</p> Signup and view all the answers

What distinguishes macro-parasites from other parasites?

<p>They can be seen with the naked eye. (A)</p> Signup and view all the answers

What is a significant feature of the life cycle of Plasmodium?

<p>It requires both a mosquito and a human host. (D)</p> Signup and view all the answers

Which of the following conditions can fungi cause in humans?

<p>Thrush (D)</p> Signup and view all the answers

What is the main advantage of protozoa forming dormant cysts?

<p>To survive adverse conditions (D)</p> Signup and view all the answers

Which factor primarily distinguishes endoparasites from ectoparasites?

<p>Location on the host (B)</p> Signup and view all the answers

How does the immune system respond to fungal infections?

<p>Using pattern recognition receptors (C)</p> Signup and view all the answers

Which is true regarding the antibiotic resistance of protozoan parasites?

<p>They can develop resistance quickly. (D)</p> Signup and view all the answers

What is the primary role of fungi in the ecosystem?

<p>Act as decomposers and nutrient recyclers (A)</p> Signup and view all the answers

What characterizes ectoparasites such as fleas and ticks?

<p>They are external and typically have short-term associations. (A)</p> Signup and view all the answers

What is an epidemic?

<p>A sudden increase in a disease within a specific area. (C)</p> Signup and view all the answers

What is a primary characteristic of biotrophic pathogens?

<p>They live and feed on living tissue. (C)</p> Signup and view all the answers

Which plant pathogen group is responsible for producing toxins that compromise plant defenses?

<p>Plant fungi (D)</p> Signup and view all the answers

How do vectors contribute to the spread of plant diseases?

<p>By carrying pathogens on their bodies or as hosts. (A)</p> Signup and view all the answers

What is a major consequence of intensive livestock farming?

<p>Enhanced spread of diseases among animals. (D)</p> Signup and view all the answers

What is the impact of chlorosis in infected plants?

<p>Inhibits photosynthesis by lacking chlorophyll. (C)</p> Signup and view all the answers

How does foot and mouth disease primarily spread among cattle?

<p>Through direct contact with infected droplets. (C)</p> Signup and view all the answers

What is a function of adhesions in pathogens like Helicobacter pylori?

<p>To attach to host cell surfaces. (B)</p> Signup and view all the answers

What describes the role of antibiotic-resistant bacteria in livestock production?

<p>They can result from excessive antibiotic use. (A)</p> Signup and view all the answers

Which of the following diseases can be transmitted to humans from animals?

<p>Anthrax (C)</p> Signup and view all the answers

What is the primary method of replication used by prokaryotic organisms?

<p>Binary fission (A)</p> Signup and view all the answers

What factor contributes to low genetic diversity in plants grown for agriculture?

<p>Selective breeding for desirable traits. (C)</p> Signup and view all the answers

What is the primary route through which the BSE prion can spread to humans?

<p>Through the consumption of contaminated beef products. (A)</p> Signup and view all the answers

Which plant pathogen can cause wilting by blocking stomata?

<p>Plant fungi (A)</p> Signup and view all the answers

What is the characteristic feature of anthrax spores?

<p>They can remain dormant and survive in soil. (D)</p> Signup and view all the answers

What is the primary way that bacteria adhere to host cells?

<p>Using pili and fimbriae (D)</p> Signup and view all the answers

How do viruses typically invade host cells?

<p>Through receptor-mediated endocytosis (D)</p> Signup and view all the answers

Which statement describes the role of thermotolerant fungi?

<p>They use heat shock proteins to survive in host environments. (C)</p> Signup and view all the answers

What is an example of a plant's physical defense against pathogens?

<p>Resin production (C)</p> Signup and view all the answers

Which mechanism is NOT a method by which plants respond to a pathogen?

<p>Endotoxin release (D)</p> Signup and view all the answers

What feature allows macroparasites such as hookworms to anchor to host tissue?

<p>Buccal capsule teeth (C)</p> Signup and view all the answers

What benefit does leaf dropping provide to a plant in response to infection?

<p>It isolates the infection. (A)</p> Signup and view all the answers

What is the primary purpose of the plant's pattern recognition receptors (PRRs)?

<p>To sense pathogen-associated molecular patterns (PAMPs) (A)</p> Signup and view all the answers

What does the hypersensitive response (HR) lead to in infected plant cells?

<p>Cell suicide (apoptosis) (D)</p> Signup and view all the answers

Which of the following is an active defense mechanism in plants?

<p>Pattern-Triggered Immunity (PTI) (C)</p> Signup and view all the answers

How do ticks prevent host blood clotting during feeding?

<p>By secreting anticoagulant molecules (D)</p> Signup and view all the answers

What is systemic acquired resistance (SAR) in plants?

<p>A whole-plant immune response. (B)</p> Signup and view all the answers

Which factor contributes to the difficulty of establishing a fungal infection in a healthy plant?

<p>Sturdy cell walls (D)</p> Signup and view all the answers

What role do immunomodulatory proteins play in macroparasite infections?

<p>Suppressing the host immune response (B)</p> Signup and view all the answers

What traditional use does tea tree oil have among the Bundjalung Aboriginal peoples?

<p>Applied as a paste to wounds (C)</p> Signup and view all the answers

How is Kakadu Plum primarily significant in traditional Aboriginal medicine?

<p>Rich source of vitamin C (C)</p> Signup and view all the answers

Which of the following plants is associated with healing properties for sores and cuts in Northern Territory tribes?

<p>Emu Bush (C)</p> Signup and view all the answers

What significant compound was found in smokebush during the AIDS epidemic?

<p>Conocurovone (B)</p> Signup and view all the answers

What issue arises from the patenting of traditional medicinal plants according to the concerns presented?

<p>It can restrict Indigenous communities from using their resources (C)</p> Signup and view all the answers

Which traditional use is attributed to the Witchetty Grub by Central Australian tribes?

<p>Used as a source of protein and skin treatment (B)</p> Signup and view all the answers

Why were Indigenous Australians overlooked in the patenting of smokebush?

<p>Their contributions were not seen as valuable (D)</p> Signup and view all the answers

What condition did eucalyptus oil traditionally treat before its modern usage?

<p>Muscle aches and fevers (D)</p> Signup and view all the answers

What role has traditional Indigenous knowledge played in the screening of smokebush by bioprospecting companies?

<p>Informed selection for screenings (A)</p> Signup and view all the answers

What notable property do the leaves of Emu Bush have according to recent studies?

<p>Antibiotic properties similar to pharmaceuticals (A)</p> Signup and view all the answers

What type of immunity is primarily mediated by B-cells?

<p>Humoral immunity (D)</p> Signup and view all the answers

What is the role of plasma cells in the immune response?

<p>To secrete antibodies (C)</p> Signup and view all the answers

Which statement about memory cells is correct?

<p>They circulate the body and respond to reinfection quickly. (A)</p> Signup and view all the answers

Which type of T-cell directly destroys infected cells?

<p>Killer T-cells (A)</p> Signup and view all the answers

What is the process called when antibodies immobilize pathogens by forming clumps?

<p>Agglutination (A)</p> Signup and view all the answers

In what way can Helper T-cells activate B-cells?

<p>Through direct contact or by releasing cytokines (C)</p> Signup and view all the answers

Which component enhances the immune response by promoting inflammation and the activity of other immune cells?

<p>Cytokines (B)</p> Signup and view all the answers

What is the key factor that distinguishes active immunity from passive immunity?

<p>Exposure to pathogens (A)</p> Signup and view all the answers

Which immune response occurs when a pathogen has entered host cells?

<p>Cell-mediated response (B)</p> Signup and view all the answers

What occurs during the clonal selection of B-cells?

<p>Specific B-cells are activated based on antigen binding. (B)</p> Signup and view all the answers

Which type of immunity is typically offered through vaccination?

<p>Active immunity (D)</p> Signup and view all the answers

What triggers the production of antibodies by plasma cells?

<p>Cytokines from helper T-cells (C)</p> Signup and view all the answers

What is the main function of suppressor T-cells in the immune system?

<p>Inhibit the immune response (B)</p> Signup and view all the answers

What is the main purpose of immunizing a community?

<p>To ensure herd immunity and prevent disease spread (D)</p> Signup and view all the answers

Which approach is part of the RICE strategy for controlling infectious diseases?

<p>Coordinating efforts on a global scale (B)</p> Signup and view all the answers

What is the primary function of insecticides?

<p>To kill insects (B)</p> Signup and view all the answers

What is the main concern regarding the increased use of pesticides?

<p>They can lead to resistance in pests (D)</p> Signup and view all the answers

What role does genetic engineering play in disease management?

<p>It alters genetic makeup for disease resistance (C)</p> Signup and view all the answers

What happens when antivirals are administered during a viral infection?

<p>They stop the replication of the virus (A)</p> Signup and view all the answers

Which of the following describes an antibiotic's action?

<p>They can be bacteriostatic or bactericidal (C)</p> Signup and view all the answers

What is a significant negative outcome of antibiotic misuse?

<p>Development of drug-resistant bacteria (C)</p> Signup and view all the answers

What characteristic of DDT raises environmental concerns?

<p>It has long-lasting toxic effects (A)</p> Signup and view all the answers

What distinguishes passive acquired immunity from other types?

<p>It involves antibodies from another organism (A)</p> Signup and view all the answers

How does proper use of antibiotics contribute to public health?

<p>By minimizing the development of resistant bacteria (B)</p> Signup and view all the answers

What was a notable impact of the WHO's vaccination campaign?

<p>Resulted in the eradication of smallpox (A)</p> Signup and view all the answers

What is one aim of public health campaigns?

<p>To educate about factors affecting disease transmission (D)</p> Signup and view all the answers

What describes the nature of antivirals in managing viral infections?

<p>They solely prevent symptoms without treating the virus (B)</p> Signup and view all the answers

What is one significant factor that can lead to the rapid spread of infectious diseases in a community?

<p>Frequent public gatherings (A)</p> Signup and view all the answers

Which type of hygiene focuses on individual cleanliness to prevent disease transmission?

<p>Personal Hygiene (B)</p> Signup and view all the answers

What role does vaccination play in disease prevention?

<p>It boosts the natural immunity of the body. (A)</p> Signup and view all the answers

What is a key procedure involved in animal quarantine?

<p>Regular sickness exams during isolation (B)</p> Signup and view all the answers

Why is communication between countries essential for controlling the spread of infectious diseases?

<p>It allows for coordinated quarantine measures. (C)</p> Signup and view all the answers

Which practice is crucial for preventing the spread of foodborne pathogens?

<p>Thorough washing of hands before preparing food (B)</p> Signup and view all the answers

What is an example of a global measure to prevent disease spread?

<p>International travel bans during outbreaks (A)</p> Signup and view all the answers

What role does salicylic acid play in a plant's response to pathogens?

<p>It stimulates the plant's defense against pathogens. (A)</p> Signup and view all the answers

How can climate influence the spread of certain infectious diseases like malaria?

<p>Increased rainfall creates breeding grounds for vectors. (A)</p> Signup and view all the answers

Which statement accurately describes the first line of defense in the human immune system?

<p>It involves physical and chemical barriers. (A)</p> Signup and view all the answers

What is an important aspect of community hygiene that prevents disease spread?

<p>Sewage and garbage disposal systems (B)</p> Signup and view all the answers

What characterizes the inflammatory response in the second line of defense?

<p>It increases blood flow and white blood cell activity. (B)</p> Signup and view all the answers

What happens during the incubation period of a pathogen?

<p>The organism may appear healthy yet be infectious. (B)</p> Signup and view all the answers

What is the primary purpose of phagocytosis in the immune response?

<p>To eliminate invading pathogens. (A)</p> Signup and view all the answers

What is the main purpose of public health campaigns in disease prevention?

<p>To promote awareness and healthy practices. (D)</p> Signup and view all the answers

How do goblet cells contribute to the first line of defense?

<p>They create a sticky layer of mucus to trap pathogens. (C)</p> Signup and view all the answers

What type of transmission involves direct contact with contaminated objects?

<p>Indirect contact transmission (A)</p> Signup and view all the answers

What triggers the release of histamine during an immune response?

<p>Damage to tissues. (A)</p> Signup and view all the answers

How does genetic engineering contribute to preventing disease spread?

<p>By altering vectors to reduce transmission. (A)</p> Signup and view all the answers

What is the role of sentinel animals in disease prevention?

<p>They serve as early warning systems for outbreaks. (A)</p> Signup and view all the answers

Which disease is transmitted by a tick bite?

<p>Lyme disease (D)</p> Signup and view all the answers

Which component of the immune system is primarily responsible for creating antibodies?

<p>B lymphocytes. (C)</p> Signup and view all the answers

What is the main function of lysozymes in the human body?

<p>To break down cell membranes of bacteria. (C)</p> Signup and view all the answers

Which experiment did Pasteur conduct to prove the role of microorganisms in fermentation?

<p>Boiling and using swan-necked flasks (D)</p> Signup and view all the answers

What is the significance of the skin's slightly acidic nature?

<p>It inhibits microbial growth. (D)</p> Signup and view all the answers

What is the first postulate of Koch's postulates?

<p>Microorganism must be found in excess numbers in diseased organisms (D)</p> Signup and view all the answers

Which cells are primarily involved in the process of phagocytosis?

<p>Macrophages. (A)</p> Signup and view all the answers

What concept did Pasteur's experiment help to disprove?

<p>The theory of spontaneous generation (B)</p> Signup and view all the answers

What is vector transmission primarily associated with?

<p>Insects or animal bites (A)</p> Signup and view all the answers

What happens to pathogens that are contained within phagolysosomes?

<p>They are killed and digested. (A)</p> Signup and view all the answers

What was one of the earliest mathematical models used to demonstrate the benefits of vaccination against smallpox?

<p>Bernouli Model (B)</p> Signup and view all the answers

Which approach did Koch use to confirm the cause of anthrax?

<p>Inoculating healthy animals with infected blood (C)</p> Signup and view all the answers

Which barrier relies on physical structures to inhibit pathogen entry?

<p>Mucous membranes. (A)</p> Signup and view all the answers

What did Pasteur develop to reduce the microbial load in food products?

<p>Pasteurization processes (B)</p> Signup and view all the answers

What was a widely held belief regarding the cause of diseases like the Black Death and Cholera in historical contexts?

<p>Bad air (D)</p> Signup and view all the answers

Which process enhances the movement of white blood cells to an infected area?

<p>Blood vessel permeability increase. (B)</p> Signup and view all the answers

What strategy did Cleopatra employ to protect herself from mosquito bites?

<p>Mosquito nets (D)</p> Signup and view all the answers

What is the result of apoptosis in immune response?

<p>It eliminates surrounding pathogens by sealing them off. (A)</p> Signup and view all the answers

Koch's method for cultivating pure cultures involved which of the following?

<p>Using solid gelatin on a flat surface (D)</p> Signup and view all the answers

Which of the following is a condition of Koch’s second postulate?

<p>Microorganism should be found solely in diseased organisms (D)</p> Signup and view all the answers

Which of the following was a cultural factor that influenced the spread of Ebola in Africa between 2013-2016?

<p>Close family interactions (C)</p> Signup and view all the answers

What is the role of the Global Outbreak Alert and Response Network (GOARN)?

<p>To detect and verify outbreaks and issue alerts (C)</p> Signup and view all the answers

Which statement best describes the Germ Theory of Disease?

<p>Specific microorganisms cause specific diseases (D)</p> Signup and view all the answers

What did John Snow famously use to track the spread of Cholera?

<p>Mapping deaths (D)</p> Signup and view all the answers

What did Pasteur claim about microorganisms and infectious diseases?

<p>Preventing their entry can reduce infections (B)</p> Signup and view all the answers

What impact did Pasteur's work have on surgery?

<p>It resulted in antiseptic methods introduced by Lister (D)</p> Signup and view all the answers

What concept was introduced by Hippocrates regarding disease prediction?

<p>Data collection and analysis (D)</p> Signup and view all the answers

What is an example of foodborne transmission of disease?

<p>Spoiled milk due to microorganisms (B)</p> Signup and view all the answers

Current disease prediction utilizes which of the following strategies?

<p>Mathematical modeling and surveillance programs (A)</p> Signup and view all the answers

What role does traditional Chinese medicine often involve in disease control?

<p>Acupuncture and herbal medicine (D)</p> Signup and view all the answers

How did Koch demonstrate that anthrax spores could cause disease without direct animal contact?

<p>By culturing anthrax in an ox's eye (D)</p> Signup and view all the answers

Which of the following is considered a method for controlling disease in Australia?

<p>National quarantine policies (C)</p> Signup and view all the answers

What is a characteristic of bush medicine used by Aboriginal Australians?

<p>Reliance on native plants and herbal practices (B)</p> Signup and view all the answers

Which of the following statements accurately reflects the belief systems in certain cultures towards healthcare?

<p>Local traditions heavily influence health practices (A)</p> Signup and view all the answers

What is the importance of recognizing Indigenous cultural and intellectual property in medicine?

<p>To ensure proper compensation for medical advancements (D)</p> Signup and view all the answers

What was the primary goal of the surveillance programs in current disease prediction?

<p>Maintain control and predict outbreaks (D)</p> Signup and view all the answers

What was the primary objective during the Delay phase of Australia's pandemic response?

<p>To prevent or slow entry of the virus into Australia (B)</p> Signup and view all the answers

What was a significant action taken during the Contain phase in Australia?

<p>Closure of schools if students were at risk (B)</p> Signup and view all the answers

Which groups were highlighted as facing a greater risk of serious illness from swine flu?

<p>Pregnant women and morbidly obese individuals (D)</p> Signup and view all the answers

What does the term 'incidence' refer to in the context of infectious diseases?

<p>The frequency of new cases over a specified period (D)</p> Signup and view all the answers

Which factor significantly contributes to the spread of dengue fever?

<p>Human mobility (A)</p> Signup and view all the answers

Which region is estimated to bear around 70% of the global burden of dengue fever?

<p>Asia-Pacific (D)</p> Signup and view all the answers

What was a major issue linked to media management during the swine flu outbreak?

<p>Frequent comparisons to 1918 pandemic (C)</p> Signup and view all the answers

How is the prevalence of a disease differentiated from its incidence?

<p>Prevalence includes all current and previous cases. (C)</p> Signup and view all the answers

Which approach was taken in the Protect phase of Australia's pandemic response?

<p>A large-scale public vaccination campaign (A)</p> Signup and view all the answers

What is a characteristic of dengue fever infections in South-East Asia?

<p>Higher incidence in children compared to adults (C)</p> Signup and view all the answers

What measures were taken to screen arrivals at Australian airports during the pandemic?

<p>Thermal imaging for flu symptoms (C)</p> Signup and view all the answers

What was the concept of mobility in relation to infectious diseases?

<p>Human movement as carriers of pathogens (B)</p> Signup and view all the answers

In which phase were customs officers actively surveilling airplane cabins?

<p>Delay phase (D)</p> Signup and view all the answers

Flashcards

Health (WHO definition)

A state of complete physical, mental, and social well-being, not just the absence of disease or infirmity.

Disease

An impairment of health or abnormal functioning, often caused by a disorder of structure or function within the body.

Infectious Diseases

Diseases that are caused by pathogens, such as bacteria, viruses, fungi, or parasites.

Non-Infectious Diseases

Conditions that are not caused by pathogens and cannot be spread from person to person. They often arise from inherited factors, environmental exposures, or lifestyle choices.

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Zoonotic Disease

A disease that can be transmitted between humans and animals.

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Parasite

An organism that lives in or on another organism, benefiting at the host's expense.

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Ectoparasite

An organism that lives on the outside of its host, like ticks or fleas.

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Endoparasite

An organism that lives inside the body of its host, like tapeworms or malaria parasites.

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What is a pathogen?

A disease-causing agent that can be either microscopic or macroscopic.

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What is virulence?

A measure of how likely a pathogen is to make its host ill. It depends on the pathogen's ability to invade tissues, the severity of damage caused, and the tissues targeted.

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What is infection?

The invasion and reproduction of a pathogen in the body. It doesn't necessarily mean the host is sick.

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What are prions?

Prions are abnormally structured proteins that cause other proteins to become abnormally structured. They are non-living and non-cellular.

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What is encephalopathy?

A fatal neurodegenerative disease caused by prions. Characterized by brain shrinkage and deterioration, resulting in progressive loss of neurons.

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What are viruses?

A virus consists of DNA or RNA enclosed in a protein coat. They are non-living and cannot reproduce on their own. Viruses invade and hijack host cells to replicate.

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What is vaccination?

A process used to reduce the incidence of viral infections by introducing a weakened or inactive form of the virus to the body, triggering an immune response.

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What are bacteria?

Bacteria are single-celled, prokaryotic organisms that lack membrane-bound organelles.

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How do bacteria reproduce?

The process where bacteria reproduce asexually by splitting into two identical daughter cells.

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Where are bacteria found?

Bacteria are found in virtually every environment, including extreme conditions, and are essential for nutrient cycling, sewage treatment, and even food production.

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What is the human microflora?

An ecosystem of bacteria and microbes that normally live on or in the human body. Most are beneficial.

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How do pathogenic bacteria cause disease?

Pathogenic bacteria can cause disease by damaging host cells, producing toxins, or outcompeting healthy bacteria.

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What is the immune response to bacterial infections?

The body's response to infection, characterized by increased blood flow to the area, inflammation, and immune cell activation.

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Reservoir (in the Chain of Infection)

A place where a pathogen can live, multiply, and reproduce, such as within a person, water, or food.

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Portal of Exit (in the Chain of Infection)

The way a pathogen leaves its reservoir and spreads to another host, like through blood, bodily fluids, or skin.

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Modes of Transmission (in the Chain of Infection)

The methods a pathogen uses to travel from the reservoir to a new host, such as direct contact, indirect contact, or vectors.

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Portal of Entry (in the Chain of Infection)

A route a pathogen can use to enter a susceptible host, like mucous membranes, the respiratory system, or broken skin.

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Susceptible Host (in the Chain of Infection)

A person or animal that is vulnerable to a disease due to factors like immune deficiency, diabetes, injury, or age.

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Direct Contact Transmission

Transmission of a pathogen through direct physical contact between an infected person and a susceptible person, such as touching, exchanging bodily fluids, or close proximity.

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Indirect Contact Transmission

Transmission of a pathogen through contact with contaminated objects or surfaces, such as sharing utensils, touching a doorknob, or using a contaminated water source.

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Vector Transmission

Transmission of a pathogen through an intermediary carrier, such as insects (like mosquitoes or ticks), animals, or contaminated water or food.

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Microbiological Culture

A technique to grow microbes in a controlled environment, allowing scientists to study them more easily.

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Inoculating Loop

Using a sterilized loop to transfer a sample of microbes to a culture medium, such as an agar plate.

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Bordetella pertussis

Bacteria that causes whooping cough, attaching to cilia in the upper respiratory system and producing toxins that damage the airway.

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Yeasts

Fungi that are unicellular and are often found in yeast.

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Mushrooms

Fungi that are multicellular, forming large structures like mushrooms.

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Fungal Enzymes

A substance that helps break down food, produced by fungi, responsible for infection symptoms.

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Tinea

A fungal infection that causes a ring-shaped rash, affecting the skin, nails, and hair.

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Trypanosoma

A protozoan that causes African sleeping sickness, a disease that affects the nervous system.

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Plasmodium

A protozoan that causes malaria, a disease spread by mosquitos.

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Vector

An organism that transmits a disease from one host to another, like a mosquito transmitting malaria.

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Macro-parasite

A large parasite that can be seen with the naked eye, living inside or on the surface of a host.

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Tapeworm

A flatworm that lives in the intestines and can grow up to 25 meters long, causing intestinal infections.

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Guinea Worm

A large nematode worm that causes Guinea worm disease, transmitted through drinking contaminated water.

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Epidemic

An increase in the occurrence of a disease within a certain area, exceeding the usual endemic level.

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Pandemic

A disease outbreak that occurs across a wider area, affecting a large percentage of the population.

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Postulate

A scientific principle accepted as true for research.

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Plant diseases

Diseases that affect plants grown for agricultural purposes.

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Intensified Farming and Disease Transmission

The spread of diseases among livestock due to close proximity and intensive farming practices.

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Biotroph

A type of plant pathogen that obtains nutrients from living plant tissue.

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Necrotroph

A type of plant pathogen that kills plant cells to obtain nutrients.

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Hyphae

Long, thread-like filaments that spread within plant tissue, absorbing nutrients.

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Sporangium

Reproductive parts of fungi that produce spores, enabling their spread.

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Plant Virus

A virus that replicates within plant cells using the plant's machinery.

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Plant Macro-parasites

Insects and mites that damage plants directly or transmit disease.

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Foot and Mouth Disease

A viral disease that affects cattle, sheep, pigs, and goats, easily spread through saliva and other contacts.

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Mad Cow Disease (BSE)

A prion-caused disease affecting cattle (Bovine Spongiform Encephalopathy), potentially transmissible to humans through contaminated food.

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Anthrax

A bacterial disease affecting cattle, sheep, and goats, transmitted through contaminated feed and water.

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Pathogen Adaptations

Strategies or adaptations used by pathogens to adhere to, enter, and survive in their hosts.

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Adhesions

Proteins or complexes that allow bacteria to bind to host cell surfaces.

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Airborne transmission

The spread of pathogens through the air, often by droplets or aerosols.

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Contaminated object transmission

The spread of pathogens through contact with contaminated objects, such as doorknobs, medical equipment, or toys.

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Food and drinking water transmission

The spread of pathogens through contaminated food or drinking water.

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Animal to person transmission

The spread of pathogens from animals to humans.

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Koch's postulates

A set of four criteria used to prove that a particular microorganism causes a particular disease.

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Postulate 1: Microorganism presence

The first postulate of Koch's postulates stating that the microorganism must be found in excess numbers in all diseased organisms and must be absent from healthy organisms.

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Postulate 2: Isolation and culture

The second postulate of Koch's postulates stating that the microorganism must be isolated from the diseased organism and grown in pure culture.

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Postulate 3: Reproduction of disease

The third postulate of Koch's postulates stating that the cultured microorganism must be capable of reproducing the same disease in a healthy organism upon inoculation.

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Postulate 4: Re-isolation and re-culture

The fourth postulate of Koch's postulates stating that the microorganisms must be re-isolated and re-cultured from the inoculated and diseased organisms.

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Pasteur's swan-neck flask experiment

A process that disproves the theory of spontaneous generation and supports the Germ Theory of Disease. It demonstrates that microorganisms can cause spoilage in broth through contamination from the air.

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Pasteurization

A process where food products are heated to a high enough temperature to kill most of the microbes, but not high enough to denature enzymes and change the taste of the substance.

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Anaerobic conditions

A process in which microorganisms are able to survive and grow without the presence of oxygen.

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Pathogen Mobility

Pathogens have appendages that help them to move quicker, like bacteria using cilia or flagella.

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Prion Adaptation

Prions are infectious proteins that 'piggyback' on other proteins, like ferritin in meat, to travel through the stomach and gut.

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Viral Adhesion

Viruses use receptors on their surface to attach to host cells, enabling them to enter and replicate.

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Viral Invasion

Viruses enter cells via receptor-mediated endocytosis, a process where they are engulfed by the cell.

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Bacterial Adhesion

Bacteria use structures called pili and fimbriae to attach to the surface of host cells.

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Bacterial Resistance

Bacterial surface adhesions help them resist being washed away by secretions like urine, mucus, and cilia.

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Bacterial Biofilms

Bacteria can form a biofilm, a protective layer that helps them resist host defenses.

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Bacterial Invasion Enzymes

Bacteria produce enzymes like collagenase to break down cell contents and facilitate invasion.

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Bacterial Endotoxins

Endotoxins released by bacteria can damage host cells, contributing to infection.

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Protozoan Protection

Protozoans, like Toxoplasma gondii, form a vacuolar membrane for protection from lysosomes within host cells.

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Protozoan Lipid Secretion

Protozoans can secrete lipids to protect themselves from attacks.

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Fungal Adhesion

Fungi use cell wall or capsule molecules to attach to host cells.

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Fungal Thermotolerance

Fungi can produce heat shock proteins to cope with host body temperatures.

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Basal Resistance

A plant's natural defenses, present even without encountering a pathogen.

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Hypersensitive Response

A localized response where the plant kills infected cells to prevent pathogen spread.

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Salicylic Acid

A chemical signal released by a plant in response to pathogen infection, spreading through the vasculature and triggering defense mechanisms in uninfected parts of the plant.

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Antigen

Any molecule that triggers an immune response. Often located on the surface of pathogens, allowing the immune system to recognize them as harmful.

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Physical Barriers

The surface of the body and its secretions, providing the first line of defense against pathogens.

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Goblet Cells

Cells specialized in producing mucus, a sticky substance that traps pathogens in bodily cavities.

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Cilia

Hair-like projections on cell surfaces that beat and sweep mucus to designated locations, such as the stomach.

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Lysozymes

Enzymes found in saliva, tears, and nasal secretions that break down the cell walls of bacteria.

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Innate Immunity

The body's second line of defense, triggered when the first line is breached, involving processes like inflammation and phagocytosis.

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Inflammation

The dilation of blood vessels causing redness, heat, swelling, and pain, bringing white blood cells to the site of infection.

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Phagocytes

Specialized white blood cells that engulf and destroy invading pathogens.

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Phagocytosis

The process of engulfing and destroying pathogens by phagocytes.

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Lymph System

A system of lymphatic vessels, lymph nodes, and lymph fluid involved in filtering cell debris and generating white blood cells.

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Apoptosis

The process of cell death that surrounds and seals off pathogens, blocking their movement and nutrient supply.

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Adaptive Immunity

The body's third line of defense, characterized by the ability to specifically recognize and target specific pathogens.

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Third Line of Defense

The third line of defense in the immune system, characterized by highly specific responses targeting particular pathogens.

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Humoral Immunity

The part of the immune system that involves antibodies found in body fluids, primarily targeting pathogens outside cells.

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B Lymphocytes (B-cells)

White blood cells formed and matured in the bone marrow, playing a crucial role in antibody-mediated immunity.

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Plasma Cells

Specialized B-cells that rapidly produce and secrete antibodies, targeting specific antigens.

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Antibodies

Proteins secreted by plasma cells that bind to specific antigens, forming antigen-antibody complexes that neutralize and destroy pathogens.

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Memory Cells

Specialized B-cells that persist after an infection, providing long-term immunity by rapidly producing antibodies upon re-exposure to the same pathogen.

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T Lymphocytes (T-cells)

White blood cells formed in the bone marrow and matured in the thymus, responsible for cell-mediated immunity.

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Killer T-cells (Cytotoxic)

T-cells that directly destroy infected cells by releasing toxic chemicals, such as perforin.

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Helper T-cells

T-cells that help activate other immune cells, including B-cells and cytotoxic T-cells.

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Suppressor T-cells

T cells that turn off the immune response, preventing excessive inflammation and autoimmune reactions.

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Memory T-cells

T cells that remain in the body after an infection, providing long-term immunity by quickly recognizing and responding to the same pathogen.

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Hormonal Response (Antibody Mediated)

Immune response involving antibodies, primarily targeting pathogens outside cells in the bloodstream or body fluids.

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Cell Mediated Response

Immune response that involves T-cells, targeting pathogens that have entered host cells or tissues.

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Active Immunity

The process by which the immune system acquires immunity to a pathogen through prior exposure, either naturally or artificially.

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Incidence

The frequency of new cases of a disease over a specified period of time. It can also be thought of as the infection rate or probability of contracting disease.

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Prevalence

The proportion of the population that have the disease at a particular point in time. Whereas incidence refers only to new cases, prevalence refers to all cases, previous and current.

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Mortality Rate

The number of deaths within a particular population as a result of a certain disease over a specified period of time.

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Mobility

Determines how easy it is for the pathogen to spread. Mobility of individuals and the portion that are immune or immunised are important factors in disease spread.

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Dengue Fever

A mosquito-borne tropical disease caused by dengue virus. Infection results in fever, headache, joint pain, and rashes.

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Dengue Vector

The Aedes type of mosquito transmits the dengue virus.

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Dengue Incidence

390 million infections globally per year. Current global estimates are that 3.9 billion in 128 countries are at risk of infection. 75% of those exposed to DF live in the Asia-Pacific region.

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Dengue Prevalence

Found in most tropical and subtropical climates. Most countries in Southeast Asia experience a higher burden of DF with frequent epidemics (3-5 years). Higher ratio of males to females. Typically affects children at a higher rate than adults. Epicentres are in major cities. Currently associated with the rainy season.

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Dengue Spread

Before 1970, only 9 countries had experienced severe dengue epidemics. The disease is now endemic in more than 100 countries in the WHO regions of Africa, the Americas, the Eastern Mediterranean, South-East Asia and the Western Pacific. The America, South-East Asia and Western Pacific regions are the most seriously affected, with Asia representing ~70% of the global burden of disease. Explosive outbreaks are occurring.

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Delay Phase

Public health action designed to slow the spread of a disease, particularly by delaying its entry into a new area.

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Contain Phase

Measures taken to prevent the spread of a disease within a community.

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Protect Phase

Measures to protect high-risk groups from severe illness during a disease outbreak.

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Delay Phase Objectives

The objective is to prevent or slow entry of the virus into Australia.

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Contain Phase Objectives

The measures aim to prevent community transmission within Australia.

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Protect Phase Objectives

The phase recognizes high-risk groups and aims to protect them through vaccination.

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Passive Acquired Immunity

Injection of antibodies produced by another organism to provide temporary immunity.

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Herd Immunity

A state where enough people are immune to a disease to prevent widespread transmission.

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Vaccination

Introducing antigens to the body to stimulate an immune response and prevent future infections.

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Pesticides

Chemicals used to kill pests that affect plants and animals, including pathogens and their vectors.

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Insecticides

A type of pesticide used to kill insects, including vectors that transmit diseases.

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Fungicides

A type of pesticide used to kill fungal pathogens that can cause infections.

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Rodenticides

A type of pesticide used to kill rodents, which can carry diseases.

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Genetic Engineering

Altering the genetic makeup of an organism to make it disease-resistant.

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Antivirals

Drugs specifically designed to treat viral infections.

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Antibiotics

Drugs used to treat bacterial infections by either killing or inhibiting their growth.

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Antibiotic Resistance

Resistance to antibiotics, where bacteria are no longer affected by the drug.

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Swine Flu (H1N1)

A pandemic of influenza A, first detected in Mexico in 2009.

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Public Health Campaign

A coordinated approach to controlling infectious diseases through resolution, information gathering, coordination, and education.

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Personal Hygiene

Personal hygiene focuses on individual practices to reduce the risk of pathogens entering the body and spreading to others. These practices include washing hands, cleaning the body and teeth, and covering your mouth when coughing or sneezing.

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Community Hygiene

Community hygiene encompasses practices that prevent the build-up of pathogens within a community. This includes proper sewage and garbage disposal, disinfection of equipment, and preventing overcrowding. It aims to create a pathogen-free environment for everyone.

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Quarantine

The process of isolating organisms for a period of time to observe the development of any potential diseases. This is essential because the organism might be carrying a pathogen during its incubation period, even if no symptoms are visible yet.

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Northern Australia Quarantine Strategy

The 'sentinel' animals are used in this strategy to monitor for potential threats. Regular checks on these animals can provide early warnings of disease outbreaks, allowing for faster response and control.

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Animal Quarantine

All animals entering Australia must undergo a period of observation at a quarantine station to ensure they are disease-free. This process is necessary to protect the country's native wildlife and agriculture from potentially harmful organisms.

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Plant Quarantine

Plants, plant parts, and products are inspected thoroughly for pests and diseases. Some products are banned from entry, while others are treated by quarantine officers to ensure pathogen destruction. Quarantine ensures that imported plants do not bring in harmful organisms.

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Human Quarantine

Human quarantine involves notifying authorities if passengers or crew display symptoms of prohibited diseases during air or sea travel. This includes measures like spraying aircraft to kill any potential disease vectors.

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Active Acquired Immunity

This type of immunity occurs when the body produces memory cells after encountering a pathogen, either through natural infection or vaccination. It offers long-term protection against the specific pathogen.

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Booster Shots

A series of vaccinations over time, often called 'booster shots', help maintain high levels of immunity by reinforcing the body's memory of the pathogen. Regular booster doses ensure long-term protection.

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Use of Pesticides

This practice involves using specialized chemicals to kill or control populations of disease-carrying insects. It aims to reduce the chances of transmission by limiting the number of vectors that can spread pathogens.

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Overcrowding

Overcrowding increases contact between individuals, making it easier for pathogens to spread. Proper city planning ensures adequate space and reduces the risk of disease transmission.

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Tea Tree Oil

A traditional Australian medicinal plant, known for its potential in treating fungal infections and acne. It was originally used by Bundjalung Aboriginal peoples from the NSW coast for wounds and throat ailments.

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Eucalyptus Oil

A native Australian plant whose leaves are used to treat muscle aches, fevers, and chills. It's now incorporated into mouthwashes and cough lollies in Western medicine.

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Emu Bush

A medicinal plant from the Northern Territory, used for treating sores, cuts, colds, headaches, and chest pains. It's even smoked to create a sterile environment for newborns and healing mothers. Recent research confirms its strong antibiotic properties.

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Kakadu Plum

A fruit native to Northern Territory and Western Australia, exceptionally rich in Vitamin C. It plays a vital role in tissue repair and collagen production, aiding wound healing and anti-aging.

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Witchetty Grub

These insects are used to treat burns and soothe skin. They also provide a good source of proteins, fats, and Vitamin C.

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Smoke Bush

A plant native to southwestern Western Australia, traditionally used as medicine by Aboriginal people. It contains conocurovone, a molecule found to be effective against HIV.

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Conocurovone

The molecule found in Smoke Bush that is effective against the HIV virus. It has been patented for AIDS treatment.

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AMRAD

This company holds the patent for using conocurovone in AIDS treatment. It was licensed by the WA government.

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Bioprospecting

The practice of exploring biological resources for commercial use, often involving the extraction of valuable compounds from plants, animals, or microorganisms.

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Oversight of Indigenous Contributions

This refers to the lack of recognition and compensation for Indigenous knowledge and contributions in the development of medicinal resources.

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What was the historical belief about disease?

The belief that disease was caused by bad air, leading to prevention strategies like avoiding bad air and using pomanders to mask smells.

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How did Bernoulli contribute to understanding disease?

Mathematical models were used to show how vaccination against smallpox increased life expectancy.

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What is the Epidemic Model?

A model which describes the spread of disease in a population based on the number of susceptible, infected, and immune individuals.

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What was the benefit of the Epidemic Model?

This model helped predict disease spread and enabled early interventions to control outbreaks.

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How did cultural practices impact Ebola spread?

The belief in family and community led to close contact and increased transmission rates, especially during caring for the sick.

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What was the role of traditional medicine in controlling disease?

Traditional Chinese medicine practices like acupuncture, herbal medicine, and diet aimed at treating illness and maintaining health.

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What are key practices for predicting disease today?

Surveillance programs, notifiable diseases, and public health interventions are crucial in monitoring and preventing disease outbreaks.

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How is modeling used in predicting disease?

Mathematical modeling allows us to understand the potential trajectory of disease: how it might spread, how interventions impact cases, and where hotspots may appear.

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How does Australia approach controlling disease?

Australia's national communicable disease control framework emphasizes preventing, detecting, and responding to disease outbreaks.

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What is the purpose of the National Notifiable Disease Surveillance System?

The National Notifiable Disease Surveillance System investigates confirmed disease cases to contain the spread and prevent further transmission.

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How does the WHO contribute to global disease control?

The World Health Organization (WHO) uses global data to predict outbreaks and coordinates international responses to public health threats.

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Describe the key practices of Bush Medicine.

Bush medicine utilizes indigenous knowledge of Australian herbs, fruits, and vegetables for medicinal purposes, often involving crushing plants for poultices or infusions.

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What scientific discoveries have emerged from Bush Medicine?

Scientists have discovered bioactive components in bush medicine with potential antimicrobial properties, showcasing the value of indigenous knowledge.

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Why is it important to protect Indigenous cultural property?

This involves recognizing and protecting the intellectual property rights of Indigenous communities who hold knowledge and practices related to medicinal plants.

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What is the significance of the smoke bush in Western Australia?

The smoke bush in Western Australia holds medicinal value and its use highlights the need for recognition and protection of Indigenous knowledge.

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Study Notes

Infectious Disease Transmission

  • Infectious diseases are caused by pathogens, which can be microorganisms (bacteria, fungi, protozoa) or macroorganisms (parasites) or non-cellular (prions, viruses).
  • Pathogens need a suitable environment (reservoir) to multiply, virulence (the ability to cause disease), and a transmission mechanism.
  • Infectious diseases can be transmitted directly (physical contact, droplet spread), indirectly (airborne, contaminated objects, vectors), or by vectors (insects, animals).
  • Epidemics involve a sudden increase in disease occurrence in a region, while pandemics are widespread across continents.
  • Zoonotic diseases are spread between animals and humans.

Pathogen Classification

  • Prions are misfolded proteins that cause neurodegenerative diseases (e.g., BSE, CJD).
  • Viruses are non-cellular genetic material (DNA or RNA) enclosed in a protein coat. They replicate inside host cells.
  • Bacteria are single-celled prokaryotic organisms with a cell wall. They reproduce asexually by binary fission.
  • Fungi are eukaryotic organisms, typically multicellular, that can reproduce sexually or asexually.
  • Protozoa are single-celled eukaryotic organisms, often found in water or soil.
  • Macroparasites are visible parasites with complex life cycles, impacting both animals and plants.

Plant and Animal Responses to Pathogens

  • Plants lack an adaptive immune system. They have innate defenses like physical barriers (cuticle, thorns) and chemical defenses (resin).
  • The hypersensitive response (HR) is a localized defense mechanism that triggers programmed cell death (apoptosis) at the site of infection.
  • Systemic acquired resistance (SAR) is a whole-plant response to infection, activating defenses in uninfected areas.
  • Plant pathogens include fungi (e.g., powdery mildew), bacteria (e.g., soft rot), viruses, and macro-parasites (insects, mites, other).
  • Animals have both innate (non-specific) and adaptive (specific) immune responses.
  • Innate responses include physical barriers (skin, mucous membranes), chemical barriers (acids, enzymes), inflammation, and phagocytosis (engulfment by immune cells).

Human Immune System Responses

  • Adaptive immunity involves B cells (humoral immunity) and T cells (cell-mediated immunity).
  • B cells produce antibodies that bind to antigens, neutralizing pathogens or triggering their destruction.
  • Memory B cells provide long-term immunity.
  • T cells (killer, helper, suppressor) directly attack infected cells.
  • Memory T cells provide long-term immunity.

Disease Spread Control

  • Hygiene practices (personal and community) reduce pathogen transmission.
  • Quarantine isolates potentially infectious individuals or materials.
  • Vaccination programs induce active immunity to prevent disease.
  • Public health campaigns educate the population about disease prevention.
  • Pesticides (insecticides, fungicides) can control insect and fungal vectors.
  • Genetic engineering creates disease-resistant organisms.

Pharmaceutical Strategies

  • Antivirals inhibit viral replication.
  • Antibiotics kill or inhibit bacterial growth.
  • Antibiotic resistance is a major concern due to overuse.

Environmental Management and Quarantine

  • Surveillance programs monitor disease incidence and prevalence.
  • Quarantine measures restrict the movement of infected individuals or materials.
  • Community measures for sewage disposal and water treatment can minimize spread of infection.

Aboriginal Protocols and Medicine

  • Aboriginal Australians have rich traditional knowledge of medicinal plants and animals.
  • This knowledge is critical for biodiversity conservation and health maintenance, in rural and remote communities.

Data Analysis and Epidemiology

  • Incidence refers to new cases of disease; prevalence includes existing and new cases.
  • Mobility influences disease spread.
  • Epidemiology examines disease patterns in populations.

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Test your knowledge on health concepts and disease classifications with this engaging quiz. From understanding definitions to modes of transmission, explore the key components of infectious and non-communicable diseases.

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