Podcast
Questions and Answers
What is the first step of HDL synthesis?
What is the first step of HDL synthesis?
- Production of Apo-AI (correct)
- Formation of pre-beta HDL
- Incorporation of cholesterol esters
- Transfer of lipids between HDL and other lipoproteins
Which transporter is responsible for transferring cholesterol and phospholipids to pre-beta HDL?
Which transporter is responsible for transferring cholesterol and phospholipids to pre-beta HDL?
- ABCG1
- ABCA1 (correct)
- CETP
- LCAT
What is the role of APO-AI in HDL synthesis?
What is the role of APO-AI in HDL synthesis?
- Acts as a cofactor for LCAT (correct)
- Allows the transfer of cholesterol to HDL in the liver
- Catabolizes cholesterol in peripheral tissues
- Transfers cholesterol to HDL in the circulation
What is the role of ABCG1 in HDL synthesis?
What is the role of ABCG1 in HDL synthesis?
Which pathway involves the transfer of lipids between HDL and other lipoproteins?
Which pathway involves the transfer of lipids between HDL and other lipoproteins?
What is the role of CETP in the exchange process?
What is the role of CETP in the exchange process?
What is the result of the action of hepatic lipases on triglyceride-rich HDL?
What is the result of the action of hepatic lipases on triglyceride-rich HDL?
What happens to Apo-A1 after being released from small HDL particles?
What happens to Apo-A1 after being released from small HDL particles?
What is the role of Apo-E in the uptake of HDL cholesterol by the liver?
What is the role of Apo-E in the uptake of HDL cholesterol by the liver?
What is the consequence of SR-B1 deficiency?
What is the consequence of SR-B1 deficiency?
What is the hallmark in the development of the atherosclerotic plaque?
What is the hallmark in the development of the atherosclerotic plaque?
Which factor is believed to trigger the formation of fatty streak in atherosclerosis?
Which factor is believed to trigger the formation of fatty streak in atherosclerosis?
What process comprises intimal thickening with subsequent accumulation of lipid-laden macrophages and extracellular matrix?
What process comprises intimal thickening with subsequent accumulation of lipid-laden macrophages and extracellular matrix?
Which cells constitute the formation of the atheroma plaque in atherosclerosis?
Which cells constitute the formation of the atheroma plaque in atherosclerosis?
What can occur as a result of the expansion of atherosclerotic lesions?
What can occur as a result of the expansion of atherosclerotic lesions?
Which process plays an important role in both the delay and accelerated progression of atherosclerotic cardiovascular disease?
Which process plays an important role in both the delay and accelerated progression of atherosclerotic cardiovascular disease?
What is believed to trigger the formation of fatty streaks in atherosclerosis?
What is believed to trigger the formation of fatty streaks in atherosclerosis?
