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Questions and Answers
What are the degenerative pathways in muscle?
What are the degenerative pathways in muscle?
Increase mitochondrial ROS, increased inflammatory cytokines, muscle protein homeostasis changes (mTOR, AKt and FOXO pathways)
Cross sectional area of muscle after age 70 is reduced by what?
Cross sectional area of muscle after age 70 is reduced by what?
How much strength is reduced after age 70?
How much strength is reduced after age 70?
Selective loss of (insert here) fibres, and reinnervation to increase (insert here) fibres
Selective loss of (insert here) fibres, and reinnervation to increase (insert here) fibres
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What does this result in?
What does this result in?
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How much fewer motor units are lower limb muscles supplied with after age 75?
How much fewer motor units are lower limb muscles supplied with after age 75?
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How much fewer extensor digitorum brevis motor units after 60 years?
How much fewer extensor digitorum brevis motor units after 60 years?
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How much fewer motor units at vastus lateralis after age 65?
How much fewer motor units at vastus lateralis after age 65?
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