Haematology Disorders: Leukaemia Epidemiology and Classification
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Questions and Answers

Which type of leukaemia is more common in males than females?

  • Acute lymphoblastic leukaemia (ALL)
  • Acute myeloblastic leukaemia (AML) (correct)
  • Chronic lymphocytic leukaemia (CLL)
  • Chronic myeloid leukaemia (CML)
  • Which type of leukaemia primarily affects older adults around 50 years of age?

  • Acute lymphoblastic leukaemia (ALL)
  • Acute myeloblastic leukaemia (AML) (correct)
  • Chronic lymphocytic leukaemia (CLL)
  • Chronic myeloid leukaemia (CML)
  • What is the most common malignancy in children and adolescents?

  • Chronic myeloid leukaemia (CML)
  • Acute lymphoblastic leukaemia (ALL) (correct)
  • Acute myeloblastic leukaemia (AML)
  • Chronic lymphocytic leukaemia (CLL)
  • Which characteristic is more pronounced in Acute Lymphoblastic Leukaemia (ALL) compared to Acute Myeloblastic Leukaemia (AML)?

    <p>Lymphadenopathy</p> Signup and view all the answers

    What is the general prognosis for Acute Lymphoblastic Leukaemia (ALL) since the 1960s?

    <p>Around 80% 5-year survival rate</p> Signup and view all the answers

    What is the WBC count indicative of Acute Leukaemias?

    <p>&gt; 100,000/µL</p> Signup and view all the answers

    Which cells are primarily identified in the diagnosis of Acute Lymphoblastic Leukaemia (ALL)?

    <p>Lymphoblasts</p> Signup and view all the answers

    What are the CNS manifestations commonly seen in Acute Leukaemias?

    <p>Headache, vomiting, and nerve palsies</p> Signup and view all the answers

    What is the main effect of marrow expansion in Acute Leukaemias?

    <p>Bone pain and tenderness</p> Signup and view all the answers

    Which risk factor is associated with Malignant diseases arising from bone marrow stem cells?

    <p>Exposure to ionizing radiation</p> Signup and view all the answers

    Which of the following is a characteristic feature of acute myeloid leukemia (AML)?

    <p>Neoplastic promyelocytes with abnormally coarse and numerous azurophilic granules</p> Signup and view all the answers

    What is the most common leukemia in adults, especially affecting those over 50 years old?

    <p>Chronic lymphocytic leukemia (CLL)</p> Signup and view all the answers

    Which gene is associated with chronic myeloid leukemia (CML)?

    <p>BCR-ABL fusion gene</p> Signup and view all the answers

    What is the characteristic finding in the peripheral blood of chronic lymphocytic leukemia (CLL)?

    <p>Increased number of lymphocytes with dense nuclear chromatin and scant cytoplasmic borders</p> Signup and view all the answers

    Which cancer is characterized by the presence of several cells with bilobed nuclei and a cell containing multiple needle-like Auer rods?

    <p>Acute myeloid leukemia (AML)</p> Signup and view all the answers

    Which leukemia is associated with the presence of 'smudge' cells in the peripheral blood during preparation of a slide?

    <p>Chronic lymphocytic leukemia (CLL)</p> Signup and view all the answers

    Which leukemia is associated with a slowly progressive course and affects adults between 25-60 years old?

    <p>Chronic myeloid leukemia (CML)</p> Signup and view all the answers

    What is the diagnostic feature of AML Myeloid blast cells?

    <p>Red-staining rod-like structures</p> Signup and view all the answers

    What is the clinical feature associated with bleeding into skin due to the rupture of capillaries?

    <p>Petechiae</p> Signup and view all the answers

    Which clinical feature is indicative of bleeding from mucous membranes?

    <p>Epistaxis</p> Signup and view all the answers

    In bleeding disorders, what is indicative of bleeding into body cavities such as joint space and intracranial hemorrhage?

    <p>Subarachnoid hemorrhage</p> Signup and view all the answers

    Which disorder can cause a reduction in platelet number leading to bleeding disorders?

    <p>Thrombocytopenia</p> Signup and view all the answers

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