22 Questions
Which type of leukaemia is more common in males than females?
Acute myeloblastic leukaemia (AML)
Which type of leukaemia primarily affects older adults around 50 years of age?
Acute myeloblastic leukaemia (AML)
What is the most common malignancy in children and adolescents?
Acute lymphoblastic leukaemia (ALL)
Which characteristic is more pronounced in Acute Lymphoblastic Leukaemia (ALL) compared to Acute Myeloblastic Leukaemia (AML)?
Lymphadenopathy
What is the general prognosis for Acute Lymphoblastic Leukaemia (ALL) since the 1960s?
Around 80% 5-year survival rate
What is the WBC count indicative of Acute Leukaemias?
> 100,000/µL
Which cells are primarily identified in the diagnosis of Acute Lymphoblastic Leukaemia (ALL)?
Lymphoblasts
What are the CNS manifestations commonly seen in Acute Leukaemias?
Headache, vomiting, and nerve palsies
What is the main effect of marrow expansion in Acute Leukaemias?
Bone pain and tenderness
Which risk factor is associated with Malignant diseases arising from bone marrow stem cells?
Exposure to ionizing radiation
Which of the following is a characteristic feature of acute myeloid leukemia (AML)?
Neoplastic promyelocytes with abnormally coarse and numerous azurophilic granules
What is the most common leukemia in adults, especially affecting those over 50 years old?
Chronic lymphocytic leukemia (CLL)
Which gene is associated with chronic myeloid leukemia (CML)?
BCR-ABL fusion gene
What is the characteristic finding in the peripheral blood of chronic lymphocytic leukemia (CLL)?
Increased number of lymphocytes with dense nuclear chromatin and scant cytoplasmic borders
Which cancer is characterized by the presence of several cells with bilobed nuclei and a cell containing multiple needle-like Auer rods?
Acute myeloid leukemia (AML)
Which leukemia is associated with the presence of 'smudge' cells in the peripheral blood during preparation of a slide?
Chronic lymphocytic leukemia (CLL)
Which leukemia is associated with a slowly progressive course and affects adults between 25-60 years old?
Chronic myeloid leukemia (CML)
What is the diagnostic feature of AML Myeloid blast cells?
Red-staining rod-like structures
What is the clinical feature associated with bleeding into skin due to the rupture of capillaries?
Petechiae
Which clinical feature is indicative of bleeding from mucous membranes?
Epistaxis
In bleeding disorders, what is indicative of bleeding into body cavities such as joint space and intracranial hemorrhage?
Subarachnoid hemorrhage
Which disorder can cause a reduction in platelet number leading to bleeding disorders?
Thrombocytopenia
Test your knowledge of the epidemiology, risk factors, and classification of leukaemia with this quiz. Explore the prevalence, gender distribution, and common risk factors associated with this group of malignant diseases arising from bone marrow stem cells.
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