39 Questions
Which layer of the stomach wall is immediately beneath the basal ends of the gastric glands?
Submucosa
What is the main component of the submucosa of the stomach wall?
Blood vessels and lymphatics
What does the mucosa of the stomach contain?
Muscularis mucosae
Which part of the stomach wall cannot be distinguished at low magnification due to the presence of tubular glands?
Mucosa
What type of tissue is predominant in the muscularis externa layer of the stomach wall?
Blood vessels and lymphatics
Which layer of the stomach wall is responsible for forming folds known as rugae?
Mucosa
What is the function of the muscularis mucosae in the stomach wall?
To anchor gastric glands
Which layer of the stomach wall forms the outermost covering of the wall?
Serosa
What characterizes the appearance of the muscularis externa layer in the stomach wall?
Smooth muscle bundles
What is a major reason for the poor overall survival in gastric cancer?
Silent nature of the disease
What has the Cancer Genome Atlas (TCGA) classification provided insights into?
Genomic landscape of gastric cancer
How does gastric cancer result from a multistep process according to the text?
Both genetic and epigenetic alterations
Which of the following is NOT mentioned as a factor influencing gastric cancer pathogenesis?
Genetic homogeneity
What do dysregulated multiple signaling pathways in gastric cancer lead to?
Increased cell proliferation
What is one area covered in the review for the special issue related to gastric cancer as mentioned in the text?
Role of Helicobacter pylori infection
What impact would clinical translation of molecular findings have on gastric cancer treatment?
Novel strategies for early detection and precision therapies
How does the dysregulation of multiple signaling pathways affect the cell cycle in gastric cancer?
Accelerates cell cycle progression
What is the significance of the molecular classifications of gastric cancer?
"TCGA classification" reveals genomic landscape and aids in precision therapies
What are the early symptoms shared by both types of gastric adenocarcinoma?
Dyspepsia and dysphagia
Which symptom is primarily associated with diffuse type gastric adenocarcinoma?
Early satiety
What are the prognostic indicators in gastric cancer mentioned in the text?
The depth of invasion and extent of metastases
What is the first choice of treatment for gastric adenocarcinoma according to the text?
Surgery
Where are extranodal lymphomas mostly located?
GI tract
What type of lymphoma is mostly secondary in the stomach?
Primary Gastric Lymphoma
Which treatment method is NOT mentioned as an alternative/additional treatment for gastric adenocarcinoma?
Physical therapy
'Linitis plastica' is associated with which type of gastric adenocarcinoma?
'Diffuse type'
'KRUKENBERG TUMOR' is primarily linked to cancer originating from which organ?
Ovary
'MALT lymphoma' stands for what type of lymphoma?
'Extranodal Marginal B zone Lymphoma'
What symptom is mainly associated with advanced-stage discovery of gastric adenocarcinoma?
Hemorrhage
Which organ can gastric cancer locally invade into as a prognostic factor?
Pancreas
What is one of the general features of fundic gland polyps?
Associated with familial adenomatous polyposis (FAP)
Which type of polyps is more commonly associated with chronic inflammation?
Hyperplastic polyps
What is a common clinical manifestation of symptomatic hyperplastic polyps?
GI bleeding that is usually evident
Which statement is true about the macroscopic examination of fundic gland polyps?
Appear as single, smooth-surfaced lesions
What is one distinguishing feature of hyperplastic polyps compared to gastric adenomas and fundic gland polyps?
Associated with chronic inflammation in their development
Which type of gastric polyps carries no cancer risk when sporadic?
Fundic gland polyps
In which age group are hyperplastic polyps most common?
50s and 60s
What is a potential symptom seen in rare cases of symptomatic gastric adenomas?
Obstruction from polyp prolapse
Fundic gland polyps are most commonly associated with which factor?
Chronic acid suppression
Explore the impact of H. pylori eradication on the overall survival in gastric cancer (GC) patients and the significance of molecular classifications in understanding the genomic landscape of GC. Learn about The Cancer Genome Atlas (TCGA) classification and its importance in identifying novel strategies for early GC detection and precision therapies.
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