Growth Hormone Antagonists

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Questions and Answers

What is the primary function of growth hormone antagonists?

  • To stimulate growth hormone production
  • To enhance growth hormone metabolism
  • To increase growth hormone receptor sensitivity
  • To prevent growth hormone from binding to its receptor (correct)

Which condition is listed as an indication for growth hormone antagonists?

  • Acromegaly (correct)
  • Hypothyroidism
  • Type 1 Diabetes
  • Osteoporosis

Which of the following is listed as a growth hormone antagonist?

  • Bromocriptine (correct)
  • Lisinopril
  • Levothyroxine
  • Insulin

What is a potential caution or contraindication when using growth hormone antagonists?

<p>Presence of any other endocrine disorder that could be exacerbated by blocking GH (B)</p> Signup and view all the answers

Which medication is listed under drug-drug interactions?

<p>Carbamazepine (B)</p> Signup and view all the answers

What is a potential adverse effect of bromocriptine when used to treat esophageal varices?

<p>Arrhythmias (B)</p> Signup and view all the answers

Besides treatment for Acromegaly, what else are Growth Hormone Antagonists indicated for?

<p>Treatment of esophageal varices (D)</p> Signup and view all the answers

Which of the following is NOT listed as an adverse effect of bromocriptine when used for esophageal varices?

<p>Fever (D)</p> Signup and view all the answers

Which of the following drugs could potentially interact with a growth hormone antagonist?

<p>Catecholamines (D)</p> Signup and view all the answers

Which of the following is another name for growth hormone antagonist?

<p>Lanreotide (C)</p> Signup and view all the answers

Flashcards

Core purpose of GH antagonists?

Prevents growth hormone from binding to its receptor.

Indications of GH antagonists?

Acromegaly and esophageal varices.

Examples of Growth Hormone Antagonists?

Bromocriptine, Lanreotide, Octreotide, Pegvisomant.

Contraindications of GH antagonists?

Presence of other endocrine disorders that can be exacerbated by blocking GH.

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Drug interactions with GH antagonists?

Carbamazepine, TCAs, alcohol, and catecholamines.

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Adverse effects of Bromocriptine for esophageal varices?

Arrhythmias, nausea, vomiting, and headache.

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Study Notes

  • Growth hormone antagonists prevent growth hormone from binding to its receptor

Indications

  • Treatment of acromegaly
  • Treatment of esophageal varices

Names

  • Bromocriptine
  • Lanreotide
  • Octreotide
  • Pegvisomant

Cautions & Contraindications

  • Use with caution in the presence of any other endocrine disorder that could be exacerbated by blocking growth hormone (GH)

Drug-Drug Interactions

  • Carbamazepine
  • TCAs
  • Alcohol
  • Catecholamines

Bromocriptine Treatment of Esophageal Varices: Adverse Effects

  • Arrhythmias
  • Nausea
  • Vomiting
  • Headache

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