Granuloma Annulare Disorder

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which age group is granuloma annulare rare in?

  • Middle age
  • Adolescence
  • Infancy (correct)
  • Young adulthood

In which age group does the generalized or disseminated variant of granuloma annulare occur more commonly?

  • Middle-aged adults (correct)
  • Young adults
  • Infants
  • Elderly adults

What has research found about the gender preponderance in granuloma annulare?

  • Consistent male preponderance
  • Equal frequency in both genders
  • Consistent female preponderance
  • Varied findings, with some studies reporting female preponderance and others finding higher frequency in males (correct)

Are cases of granuloma annulare typically sporadic or familial?

<p>Sporadic (B)</p> Signup and view all the answers

Which form of granuloma annulare occurs more frequently in children and young adults?

<p>Localized annular form (C)</p> Signup and view all the answers

Where on the body are the sites of predilection for granuloma annulare lesions?

<p>Dorsal hands, feet, ankles, lower limbs, and wrists (C)</p> Signup and view all the answers

What is the typical diameter range of the annular or arcuate lesions in granuloma annulare?

<p>1 to 5 cm (C)</p> Signup and view all the answers

Which color(s) may the annular or arcuate lesions in granuloma annulare be?

<p>Skin colored, erythematous, or violaceous (B)</p> Signup and view all the answers

What is the texture of the annular margin in granuloma annulare?

<p>Firm to palpation (D)</p> Signup and view all the answers

What is the most common morphology of generalized granuloma annulare?

<p>Widespread papules (A)</p> Signup and view all the answers

Which age group is the generalized form of granuloma annulare said to comprise 8% to 15% of cases?

<p>Adults (D)</p> Signup and view all the answers

What is the most common form of granuloma annulare?

<p>Localized with annular lesions (D)</p> Signup and view all the answers

What characterizes the subcutaneous form of granuloma annulare?

<p>Firm to hard, usually asymptomatic nodules located in the deep dermis and subcutaneous tissues (D)</p> Signup and view all the answers

Where are the nodules of subcutaneous granuloma annulare most commonly located?

<p>Anterior lower legs (B)</p> Signup and view all the answers

What is the characteristic feature of the perforating type of granuloma annulare?

<p>Central umbilication (C)</p> Signup and view all the answers

Where is the generalized form of granuloma annulare most commonly found?

<p>Trunk and extremities (A)</p> Signup and view all the answers

What is a rare variant of granuloma annulare characterized by transepidermal elimination of necrobiotic collagen?

<p>Perforating type of granuloma annulare (A)</p> Signup and view all the answers

What is a common complaint of patients with the perforating type of granuloma annulare?

<p>Pruritus and pain (B)</p> Signup and view all the answers

What is a reported characteristic of macular lesions in granuloma annulare in adult women?

<p>Erythematous, redbrown, or violaceous patches without an annular rim (C)</p> Signup and view all the answers

What is the observed feature alongside macular lesions in granuloma annulare?

<p>Arcuate dermal erythema (D)</p> Signup and view all the answers

Where are the macular lesions in granuloma annulare commonly found in adult women?

<p>Anywhere on the body (B)</p> Signup and view all the answers

What is a reported association with painful lesions on the hands in granuloma annulare?

<p>Joint disease (B)</p> Signup and view all the answers

In which disorder are granuloma annulare-like skin lesions and joint disease found?

<p>Interstitial granulomatous dermatitis with arthritis (C)</p> Signup and view all the answers

What is the suspected triggering factor for granuloma annulare lesions in children?

<p>Nonspecific mild trauma (D)</p> Signup and view all the answers

Which drug therapy has been associated with a granuloma annulare-like reaction?

<p>Anti-inflammatory drugs (B)</p> Signup and view all the answers

What has been linked to the development of interstitial granulomatous drug reaction?

<p>Calcium channel blockers (C)</p> Signup and view all the answers

Where is the predilection for granuloma annulare lesions in patients after bacille Calmette–Guérin immunization?

<p>Vaccination sites (C)</p> Signup and view all the answers

What is believed to represent a granulomatous reaction to actinic elastosis?

<p>Annular elastolytic giant cell granuloma (C)</p> Signup and view all the answers

What drug therapy has been associated with an observed granuloma annulare-like reaction?

<p>Gold therapy (A)</p> Signup and view all the answers

What is considered a distinct entity but may mimic granuloma annulare?

<p>Interstitial granulomatous drug reaction (B)</p> Signup and view all the answers

What triggering factor has been implicated in the development of granuloma annulare?

<p>Viral infections (C)</p> Signup and view all the answers

In which type of infection did chronic relapsing granuloma annulare flare due to the Koebner phenomenon?

<p>Scabies infestation (C)</p> Signup and view all the answers

Which disease has been found to be associated with the development of granuloma annulare?

<p>Active tuberculosis (C)</p> Signup and view all the answers

What is not included on the proposed mechanisms for the pathogenic mechanisms?

<p>Bacterial infection leading to inflammation and tissue damage (C)</p> Signup and view all the answers

What disease is granuloma annulare primarily associated with?

<p>Thyroid disease (D)</p> Signup and view all the answers

Which type of diabetes is primarily linked to granuloma annulare?

<p>Type 1 insulin-dependent diabetes (B)</p> Signup and view all the answers

What malignancy is granuloma annulare primarily associated with in adult patients?

<p>Leukemia (D)</p> Signup and view all the answers

Where is granuloma annulare commonly found in patients with thyroid disease?

<p>Hypothyroidism (A)</p> Signup and view all the answers

Where is the increased prevalence of dyslipidemia commonly found in patients with granuloma annulare?

<p>In cases with an annular morphology (A)</p> Signup and view all the answers

In which type of granuloma annulare is the increased prevalence of dyslipidemia more commonly found?

<p>Generalized granuloma annulare (A)</p> Signup and view all the answers

What is the main reason for obtaining a specimen for histopathologic examination in granuloma annulare?

<p>To rule out generalized granuloma annulare or subcutaneous nodular disease (C)</p> Signup and view all the answers

What is the characteristic histopathologic finding in granuloma annulare?

<p>Devoid of nuclei and marked by a loss of definition of the collagen bundles (A)</p> Signup and view all the answers

At what magnification is the diagnosis of granuloma annulare best made?

<p>Low magnification (C)</p> Signup and view all the answers

What is the typical appearance of the inflammation foci in granuloma annulare?

<p>Oval foci with a central core of altered collagen surrounded by a wall of palisaded histiocytes (B)</p> Signup and view all the answers

What is necessary when the presentation of granuloma annulare is atypical, lesions are symptomatic, or the diagnosis is in doubt?

<p>Histopathologic analysis (A)</p> Signup and view all the answers

Where are the changes usually observed in granuloma annulare?

<p>Upper and middle dermis (D)</p> Signup and view all the answers

What is the predominant pattern of inflammation in the generalized form of granuloma annulare?

<p>Interstitial, nonpalisaded pattern (D)</p> Signup and view all the answers

Which cells are admixed with histiocytes in the granuloma and in a perivascular distribution?

<p>Lymphocytes and plasma cells (D)</p> Signup and view all the answers

What may be necessary to demonstrate the necrobiotic plug in perforating granuloma annulare?

<p>Examination of serial sections (B)</p> Signup and view all the answers

What is the characteristic feature of subcutaneous granuloma annulare?

<p>Large foci of necrobiosis in the deep dermis and subcutaneous fat (C)</p> Signup and view all the answers

What is the usual treatment options for granuloma annulare?

<p>Awaiting spontaneous resolution, topical steroids, and intralesional steroids (A)</p> Signup and view all the answers

How long do most cases of localized granuloma annulare take to resolve spontaneously?

<p>Within 2 years (D)</p> Signup and view all the answers

What is a reported consequence of generalized granuloma annulare?

<p>Scarring and milia formation (B)</p> Signup and view all the answers

What diagnostic exam may be considered in the evaluation of generalized granuloma annulare?

<p>Lipid studies (C)</p> Signup and view all the answers

Flashcards are hidden until you start studying

More Like This

Granuloma and Tuberculosis Quiz
10 questions
Granuloma and Tuberculosis Quiz
5 questions
Granuloma and Panniculitis Quiz
52 questions
Granuloma Mediastinum and Fibrosis
42 questions
Use Quizgecko on...
Browser
Browser