Gram Positive Bacteria Classification
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Questions and Answers

What type of disease is diphtheria primarily caused by?

  • Gram-positive rods (correct)
  • Viruses
  • Gram-negative rods
  • Anaerobic bacteria
  • Which species is primarily responsible for foodborne listeriosis?

  • Clostridium perfringens
  • Listeria monocytogenes (correct)
  • Corynebacterium diphtheriae
  • Bacillus anthracis
  • What is the mortality rate of untreated cutaneous anthrax?

  • Twenty percent (correct)
  • Near 100 percent
  • Fifty percent
  • Five percent
  • What is a characteristic feature of pulmonary anthrax?

    <p>Hemorrhagic lymphadenitis (A)</p> Signup and view all the answers

    Which Clostridium species is associated with pseudomembranous colitis?

    <p>C. difficile (C)</p> Signup and view all the answers

    What disease is primarily associated with the bacterium Clostridium tetani?

    <p>Tetanus (A)</p> Signup and view all the answers

    Which of the following diseases is caused by Clostridium perfringens?

    <p>Gas gangrene (D)</p> Signup and view all the answers

    Which condition is characterized by severe, swollen malignant pustules?

    <p>Cutaneous anthrax (A)</p> Signup and view all the answers

    What type of hemolytic activity is associated with γ-Hemolytic streptococci?

    <p>They cause no color change or lysis of red blood cells. (A)</p> Signup and view all the answers

    Which group of β-Hemolytic streptococci is clinically considered the most important?

    <p>Groups A and B (B)</p> Signup and view all the answers

    What is the primary pathogen represented by Group A β-Hemolytic Streptococci?

    <p>Streptococcus pyogenes (C)</p> Signup and view all the answers

    How can S.agalactiae be transmitted to infants?

    <p>From an infected mother at birth. (B)</p> Signup and view all the answers

    What shape do S.pneumoniae bacteria typically exhibit?

    <p>Lancet-shaped, often in pairs (C)</p> Signup and view all the answers

    Which of the following is known to cause dental caries?

    <p>Streptococcus mutans (B)</p> Signup and view all the answers

    What capability do some strains of S.pyogenes have?

    <p>They can invade intact skin and mucous membranes. (D)</p> Signup and view all the answers

    The clinically important enterococci species include which of the following?

    <p>E.faecalis and E.faecium (C)</p> Signup and view all the answers

    What condition can arise from infected heart valves in at-risk patients?

    <p>Subacute bacterial endocarditis (B)</p> Signup and view all the answers

    Which patients should receive prophylactic penicillin before dental procedures?

    <p>Patients with rheumatic, congenital, or arteriosclerotic valvular disease (B)</p> Signup and view all the answers

    What is vegetation in the context of bacterial endocarditis?

    <p>A tissue outgrowth composed of fibrin, bacteria, and blood platelets (D)</p> Signup and view all the answers

    Which species of Staphylococcus is noted for causing food poisoning and toxic shock syndrome?

    <p>Staphylococcus aureus (A)</p> Signup and view all the answers

    Which of the following Staphylococcus species is primarily associated with urinary tract infections, particularly cystitis in women?

    <p>Staphylococcus saprophyticus (C)</p> Signup and view all the answers

    What is the primary concern regarding coagulase-negative staphylococci in medical settings?

    <p>They are important agents of hospital-acquired infections with implants and catheters. (A)</p> Signup and view all the answers

    Which condition is primarily caused by Staphylococcus epidermidis?

    <p>Prosthetic implant infections (C)</p> Signup and view all the answers

    What is the main characteristic of Staphylococcus aureus among other staphylococcal species?

    <p>It is one of the most virulent of the genus Staphylococcus. (A)</p> Signup and view all the answers

    What type of paralysis is caused by the botulinum toxin produced by Clostridium botulinum?

    <p>Flaccid paralysis (B)</p> Signup and view all the answers

    Which of the following conditions can be caused by Clostridium perfringens?

    <p>Gas gangrene (D)</p> Signup and view all the answers

    Why is tetanus considered rare in developed countries?

    <p>Widespread immunization against its exotoxin (D)</p> Signup and view all the answers

    Which of the following is a lethal dose of botulinum toxin for a human?

    <p>2μg or less (B)</p> Signup and view all the answers

    What is a common form of food poisoning associated with Clostridium perfringens?

    <p>Food poisoning (A)</p> Signup and view all the answers

    How does Clostridium tetani generally enter the body?

    <p>Via contaminated soil in small wounds (B)</p> Signup and view all the answers

    What severe condition can occur as a complication by antimicrobial drug treatment?

    <p>Diarrhea (B)</p> Signup and view all the answers

    Which formed toxin makes Clostridium botulinum a potential biological weapon?

    <p>Botulinum toxin (A)</p> Signup and view all the answers

    What characteristic is used primarily for the classification of medically important bacteria?

    <p>Morphologic and biochemical characteristics (C)</p> Signup and view all the answers

    Which of the following is NOT a type of Gram-positive bacteria?

    <p>Escherichia coli (C)</p> Signup and view all the answers

    What is the genus of the bacteria that causes a clear ring around colonies on blood agar due to gross lysis of red blood cells?

    <p>Streptococcus (A)</p> Signup and view all the answers

    Which of the following correctly defines the scientific naming of a bacterium?

    <p>The species name follows the genus name in lowercase (C)</p> Signup and view all the answers

    Which Gram-positive cocci can be classified as α-Hemolytic?

    <p>Streptococcus pneumoniae (D)</p> Signup and view all the answers

    Which of the following bacteria is classified as a spore-forming rod (bacilli)?

    <p>Clostridium (B)</p> Signup and view all the answers

    What type of Gram-positive cocci are known to form clusters?

    <p>Staphylococci (D)</p> Signup and view all the answers

    What unique feature do β-Hemolytic streptococci exhibit on blood agar?

    <p>Clear zone of lysis (D)</p> Signup and view all the answers

    Flashcards

    γ-Hemolytic Streptococci

    Streptococci that don't cause a color change or lysis (breakdown) of red blood cells.

    Lancefield Antigen

    A polysaccharide in the cell walls of many streptococci, responsible for the immune response.

    Lancefield Grouping

    A system for classifying streptococci based on variations in their Lancefield antigen.

    Streptococcus pyogenes

    The most clinically important member of Group A β-hemolytic streptococci, known for causing various infections.

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    Streptococcus pneumoniae

    A type of streptococci that causes various infections, including meningitis and pneumonia.

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    Streptococcus agalactiae

    A member of Group B streptococci, commonly found in the vaginal and intestinal tracts.

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    Enterococci

    A group of bacteria that can cause infections, including those in the urinary tract.

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    Viridans Streptococci

    A group of streptococci that are part of the normal oral flora, but can contribute to dental caries (cavities).

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    Subacute Bacterial Endocarditis

    A potentially serious infection of the heart valves caused by bacteria entering the bloodstream.

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    Bacteremia

    The presence of bacteria in the bloodstream

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    Streptococcal Endocarditis

    A type of bacterial infection that affects the heart valves and can lead to subacute bacterial endocarditis

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    Vegetation (in the context of endocarditis)

    An abnormal growth on a heart valve, often composed of fibrin, bacteria, and blood platelets.

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    Staphylococcus

    A type of bacteria known for causing various infections, including skin infections, food poisoning, and toxic shock syndrome. The most virulent species is Staphylococcus aureus.

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    Coagulase-Negative Staphylococci (CNS)

    A type of bacteria that often causes infections related to medical devices, such as implants and catheters. Staphylococcus epidermidis is a common example.

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    Urinary Tract Infection (UTI) caused by Staphylococcus

    A type of bacterial infection that often occurs in the urinary tract, especially in women. Staphylococcus saprophyticus is a common cause.

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    Toxic Shock Syndrome (TSS)

    A condition often caused by Staphylococcus aureus, characterized by a sudden onset of high fever, low blood pressure, and rash. It can be life-threatening.

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    What is the basis of bacterial classification?

    A classification system for medically important bacteria based on observable characteristics such as shape and biochemical properties.

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    What is the scientific nomenclature of bacteria?

    A system for naming organisms that utilizes a two-part name; the first part identifies the genus and the second identifies the species.

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    What are Gram-positive bacteria?

    Bacteria that stain purple with the Gram stain due to the presence of a thick peptidoglycan layer in their cell wall.

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    What are Gram-positive cocci?

    A type of Gram-positive bacteria that are spherical in shape.

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    What is Streptococcus?

    A genus of Gram-positive cocci that are known for their tendency to form chains of cells.

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    What is α-hemolysis?

    A type of hemolytic activity displayed by some bacteria, characterized by the partial breakdown of red blood cells in blood agar, resulting in a green discoloration around the bacterial colony.

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    What is β-hemolysis?

    A type of hemolytic activity displayed by some bacteria, characterized by the complete breakdown of red blood cells in blood agar, resulting in a clear zone around the bacterial colony.

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    What are free-living bacteria?

    Free-living bacteria that don't require a host cell for survival.

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    Corynebacterium diphtheriae

    A bacterial genus known for causing diphtheria, a potentially fatal respiratory illness.

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    Listeria species

    Slender, short, gram-positive rods that don't form spores. L. monocytogenes is a common foodborne pathogen.

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    Bacillus anthracis

    A type of bacteria known for causing anthrax, a serious infectious disease.

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    Cutaneous Anthrax

    A type of anthrax that affects the skin, often leaving a black, swollen pustule.

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    Pulmonary Anthrax

    A type of anthrax that infects the lungs, often fatal if untreated.

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    Clostridia

    A genus of bacteria, known for causing various illnesses.

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    Clostridium tetani

    A toxin-producing bacteria responsible for tetanus, a serious muscle-contracting disease.

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    Clostridium botulinum

    A bacteria responsible for botulism, a rare but serious food poisoning.

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    Clostridium perfringens

    A type of bacteria known for causing gas gangrene, a serious condition where tissue dies due to lack of oxygen.

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    Botulism

    A severe, potentially fatal illness caused by the toxin produced by Clostridium botulinum.

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    Tetanus

    A serious bacterial infection that causes painful muscle spasms, usually resulting from contaminated wounds.

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    Botulinum toxin

    A neurotoxin produced by Clostridium botulinum, considered one of the most potent toxins known.

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    Botulism (Food poisoning)

    A life-threatening condition caused by the toxin of Clostridium botulinum, characterized by muscle weakness and paralysis.

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    Wound botulism

    A form of botulism where the toxin enters the body through a wound.

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    Infant botulism

    Botulism that affects infants due to ingestion of spores from contaminated food or honey.

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    Study Notes

    Gram Positive Bacteria

    • Gram-positive bacteria are classified primarily by morphology (appearance) and biochemical characteristics.
    • This classification only includes medically important bacteria.
    • Scientific nomenclature: Italicize family, genus, and species. Capitalize the first letter of the family and genus names. Capitalize the first letter of kingdom, phylum, class, order, and suborder. All other words are lowercase.
    • Binary genus-species system is used (e.g., Salmonella enterica, Escherichia coli, Staphylococcus aureus).
    • Gram-positive bacteria can be cocci (spherical) or rods (elongated).
    • They can be spore-forming or non-spore-forming.
    • Important examples of gram-positive cocci are Streptococcus, Staphylococcus, Enterococci and Viridans streptococci.
    • Important examples of gram-positive rods are Bacillus, Clostridium, Corynebacterium, and Listeria.

    Classification of Medically Important Bacteria

    • Bacteria are often classified based on their characteristics like morphology, spore-forming ability, and other biochemical properties.
    • Gram-positive and gram-negative types are different on the basis of their cell wall characteristics.
    • Examples: Streptococcus, Staphylococcus, and Enterococci are gram-positive cocci.
    • Important gram-negative bacteria include Escherichia coli, Listeria, Corynebacterium.
    • The study of gram-positive and gram-negative bacteria is important for understanding bacterial infections and disease processes.

    Hemolytic Properties on Blood Agar

    • a-hemolytic streptococci cause a change in the hemoglobin in red blood cells on blood agar, resulting in a green pigment that forms a ring around the colony.
    • ẞ-hemolytic streptococci cause gross lysis (destruction) of red blood cells, showing a clear ring around the colony.
    • y-hemolytic streptococci do not cause any color change or lysis (destruction) of red blood cells on blood agar.

    Serological (Lancefield) Groupings

    • Many streptococci have a polysaccharide in their cell wall that is antigenic (generating an immune response).
    • The Lancefield scheme classifies mainly beta-hemolytic streptococci into groups A through U.
    • The medically most important groups of beta-hemolytic streptococci are types A and B.

    Group A B-Hemolytic Streptococci

    • Streptococcus pyogenes is one of the most frequent bacterial pathogens in humans.
    • Can invade intact skin or mucous membranes.
    • A small inoculum (amount) is enough for infection.
    • Some strains cause post-infectious sequelae (e.g., rheumatic fever and acute glomerulonephritis).

    Streptococcus pneumoniae

    • Gram-positive, nonmotile, encapsulated cocci (pairs).
    • They are lancet-shaped.
    • Common cause of pneumonia, otitis media, meningitis, and bacteremia/sepsis.

    Enterococci

    • Important species are E. faecalis and E. faecium.
    • These bacteria can be y, β, or nonhemolytic.

    Viridans Streptococci

    • A group of streptococci found in the mouth.
    • S. mutans and other species cause dental caries.
    • Can cause subacute bacterial endocarditis in patients with abnormal or damaged heart valves.

    Gram-positive rods

    • The slides provide information on various gram-positive rods such as Bacillus, Corynebacterium, and Listeria.
    • The slides describe characteristics like morphology, growth conditions needed, and diseases caused by each species.

    Clostridia

    • Anaerobic gram-positive rods of medical importance.
    • C. perfringens causes histotoxic infections (myonecrosis) and food poisoning.
    • C. difficile causes pseudomembranous colitis.
    • C. tetani causes tetanus.
    • C. botulinum causes botulism

    Staphylococcus

    • Staphylococcus aureus is one of the most virulent species.
    • Common cause of bacterial and food poisoning.
    • Staphylococcus epidermidis causes prosthetic implant infections.
    • Staphylococcus saprophyticus causes urinary tract infections.

    Coagulase-Negative Staphylococci

    • S. epidermidis and S. saprophyticus are important causes of common CNS infections, and frequently found in hospital settings and are linked with the infections from implanted devices and catheters.

    (Other information)

    • Information on diseases, diagnosis, and treatment is provided in the slides, but this has been compiled into summary form.

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    Gram Positive Bacteria PDF

    Description

    This quiz covers the classification of gram-positive bacteria based on their morphology and biochemical characteristics. You will learn about important examples and their scientific nomenclature. Test your knowledge of bacteria that are medically significant.

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