Gram-Negative Bacterial Cell Wall Structure

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What is the function of the outer membrane in Gram-negative bacteria?

Acts as a protective barrier against harmful substances

What is the role of Lipopolysaccharide (LPS) in Gram-negative bacteria?

Contributes to the structural integrity of the outer membrane

How do Gram-negative bacteria protect themselves from attack by most peptidases?

By incorporating D-amino acids into their peptidoglycan structure

What are porins in Gram-negative bacteria?

Proteins that form channels in the outer membrane for nutrient transport

What is the core polysaccharide component of Lipopolysaccharide (LPS) responsible for?

Attaching the LPS to the lipid A portion

How do Gram-negative bacteria protect themselves from harmful substances in their environment?

By utilizing porins for selective permeability

What is the function of the outer membrane in Gram-negative bacteria?

Barrier to certain substances like antibiotics and enzymes

What is the role of lipopolysaccharides (LPS) in the outer membrane of Gram-negative bacteria?

Helps in evading phagocytosis and complement actions

How does the outer membrane of Gram-negative bacteria affect antibiotic effectiveness?

Provides a barrier to certain antibiotics

What are porins and what is their function in the outer membrane of Gram-negative bacteria?

Proteins that form channels and permit passage of molecules

What is the function of the adhesion sites in the Gram-negative wall?

Strengthen the wall and hold the outer membrane in place

Why is the high concentration of degradative enzymes and transport proteins in the periplasm important?

Substances can move into the cell through the adhesion sites instead of the periplasm

What is the function of the outer membrane in bacteria?

Prevents loss of constituents like periplasmic enzymes

Which group of bacteria are able to survive without cell walls?

Mycoplasmas

What is the function of sterols in the cytoplasmic membranes of mycoplasmas?

Add strength and rigidity to the membrane

Which enzyme attacks peptidoglycan by hydrolyzing the bond that connects N-acetylmuramic acid with N-acetylglucosamine?

Lysozyme

What does penicillin inhibit in bacteria?

Peptidoglycan synthesis

What happens to Gram-positive bacteria when incubated with penicillin in an isotonic solution?

Converted to protoplasts that continue to grow normally

Learn about the structure of the Gram-negative bacterial cell wall, including the connection between the outer membrane and peptidoglycan. Explore the role of adhesion sites in strengthening the wall and maintaining membrane integrity.

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