Gram-Negative Bacteria Overview
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Questions and Answers

Which species of Neisseria is responsible for gonorrhea?

  • Neisseria lactamica
  • Neisseria sicca
  • Neisseria meningitidis
  • Neisseria gonorrhoeae (correct)
  • What type of bacteria is Neisseria classified as?

  • Gram-negative rods
  • Gram-positive rods
  • Gram-negative cocci (correct)
  • Gram-positive cocci
  • Which of the following is NOT a method of transmission for Neisseria gonorrhoeae?

  • Airborne transmission (correct)
  • Sexual contact
  • Through an infected birth canal
  • Direct contact with infected fluids
  • Which clinical sample commonly shows N. gonorrhoeae inside polymorphonuclear leukocytes?

    <p>Clinical samples from infected patients</p> Signup and view all the answers

    What type of organism is Neisseria meningitidis a frequent cause of?

    <p>Meningitis</p> Signup and view all the answers

    Which of the following pairs of Neisseria species are indistinguishable under the microscope?

    <p>N. meningitidis and N. gonorrhoeae</p> Signup and view all the answers

    What characteristic of N. gonorrhoeae defines its physical appearance?

    <p>Nonmotile diplococci</p> Signup and view all the answers

    Neisseria gonorrhoeae is primarily associated with which type of infections?

    <p>Sexually transmitted infections</p> Signup and view all the answers

    Which of the following genera includes organisms that can cause infections in both the gastrointestinal tract and outside of it?

    <p>Salmonella</p> Signup and view all the answers

    What characteristic do all gastrointestinal Gram-negative rods share?

    <p>They contain lipopolysaccharide (LPS).</p> Signup and view all the answers

    Which organism is commonly known for causing infections in the respiratory system and joints?

    <p>Moraxella</p> Signup and view all the answers

    Which of the following pathogens is considered opportunistic?

    <p>E. coli</p> Signup and view all the answers

    What is the primary mode of transmission for organisms causing gastrointestinal diseases?

    <p>Fecal contamination</p> Signup and view all the answers

    Which feature is commonly associated with E. coli that aids in its pathogenicity?

    <p>Fimbriae or pili</p> Signup and view all the answers

    Which of the following is mainly recognized for causing primarily gastrointestinal diseases?

    <p>Shigella</p> Signup and view all the answers

    Which of the following is NOT a classic feature of acinetobacter species?

    <p>They are motile.</p> Signup and view all the answers

    What is the primary mode of transmission for intestinal diseases caused by E. coli?

    <p>Fecal/oral route via contaminated food and water</p> Signup and view all the answers

    Which strain of E. coli is most commonly associated with severe bloody diarrhea due to its toxin production?

    <p>Enterohemorrhagic E. coli (EHEC) O157:H7</p> Signup and view all the answers

    What primarily increases the severity of infections from E. coli O104:H4?

    <p>Presence of verotoxin alongside enteroaggregative features</p> Signup and view all the answers

    What is a common cause of diarrhea in infants associated with poor sanitation?

    <p>Enteropathogenic E. coli (EPEC)</p> Signup and view all the answers

    Which condition is commonly caused by E. coli in sterile areas of the body?

    <p>Urinary tract infections (UTI)</p> Signup and view all the answers

    Which of the following E. coli strains leads to a dysentery-like syndrome?

    <p>Enteroinvasive E. coli (EIEC)</p> Signup and view all the answers

    What complication is associated with infections caused by EHEC, especially strain O157:H7?

    <p>Hemolytic uremic syndrome (HUS)</p> Signup and view all the answers

    Which mechanism is commonly utilized by Enteroaggregative E. coli (EAEC) for persistence in the host?

    <p>Biofilm formation</p> Signup and view all the answers

    Which organism is primarily responsible for neonatal meningitis within the first month of life?

    <p>E. coli</p> Signup and view all the answers

    What is a common symptom associated with Salmonella gastroenteritis?

    <p>Fever</p> Signup and view all the answers

    Which characteristic is true of enteric (typhoid) fever caused by Salmonella serotype typhi?

    <p>It can lead to abdominal symptoms and fever.</p> Signup and view all the answers

    What type of lesions can Campylobacter cause in the intestine?

    <p>Ulcerative inflammatory lesions</p> Signup and view all the answers

    What toxin is associated with Shigella species and contributes to its pathogenicity?

    <p>Shiga toxin</p> Signup and view all the answers

    Which feature is characteristic of Vibrio organisms?

    <p>Curved and rod-shaped</p> Signup and view all the answers

    Which of the following is a common symptom of Shigella infection?

    <p>Diarrhea with blood</p> Signup and view all the answers

    What is the typical clinical outcome for patients suffering from enteric (typhoid) fever?

    <p>Mortality of approximately 15%</p> Signup and view all the answers

    What disease is primarily caused by members of the genus Brucella in humans?

    <p>Brucellosis</p> Signup and view all the answers

    Which organism is most associated with respiratory tract infections?

    <p>Legionella</p> Signup and view all the answers

    Which of the following is NOT a known pathogen of humans?

    <p>B. ovis</p> Signup and view all the answers

    What kind of infections does Pseudomonas aeruginosa primarily cause?

    <p>Nosocomial infections</p> Signup and view all the answers

    Which genus is the causative agent of whooping cough?

    <p>Bordetella</p> Signup and view all the answers

    What is the primary clinical manifestation of full-blown cholera?

    <p>Profuse watery diarrhea known as rice-water stools</p> Signup and view all the answers

    Which species of Yersinia is known to cause bubonic plague?

    <p>Yersinia pestis</p> Signup and view all the answers

    What type of motility is exhibited by members of the genus Helicobacter?

    <p>Corkscrew motility resulting from multiple polar flagella</p> Signup and view all the answers

    What is the leading cause of bacterial meningitis in infants and very young children?

    <p>Haemophilus influenzae</p> Signup and view all the answers

    Which condition is caused by the genus Bordetella?

    <p>Whooping cough</p> Signup and view all the answers

    What is a common characteristic of pneumonic plague during epidemics?

    <p>It may develop from bubonic or septicemic plague</p> Signup and view all the answers

    How does H.influenzae meningitis clinically present?

    <p>Indistinguishable from other purulent meningitides</p> Signup and view all the answers

    Which species is not classified under the genus Yersinia?

    <p>Yersinia cholera</p> Signup and view all the answers

    Study Notes

    Gram-Negative Bacteria

    • Gram-negative bacteria are a diverse group of bacteria
    • Includes cocci and bacilli forms
    • Some are straight, some are curved
    • Includes enteric bacteria, respiratory organisms, zoonotic organisms, etc.

    Cocci/Coccobacilli

    • Neisseria: Contains Neisseria gonorrhoeae and Neisseria meningitidis
      • Neisseria gonorrhoeae: Causes gonorrhea, sexually transmitted
      • Neisseria meningitidis: Causes meningitis; frequently in young children
    • Moraxella: Non-motile, gram-negative coccobacilli
    • Haemophilus: Causes infections of the respiratory system
    • Bordatella: Whooping cough
    • Brucella: Brucellosis (undulant fever)

    Bacilli

    • Campylobacter: Curved, spiral, or S-shaped organisms; causes gastroenteritis and enteritis, including traveler's diarrhea
    • Helicobacter pylori: Curved or spiral organisms; causes gastritis, duodenal and gastric ulcers, stomach cancer
    • Vibrio: Short, curved, rod-shaped organisms; causes cholera
    • Enterobacteriaceae: A large family, including many pathogens of GI tract as well as those causing urinary tract infections
    • Escherichia coli (E. coli): Part of the normal gut flora, but pathogenic strains exist, and can cause enteritis, meningitis
    • Salmonella: Causes gastroenteritis and enteric (typhoid) fever
    • Shigella:Causes shigellosis, characterized by bloody diarrhea
    • Klebsiella: Causes urinary tract infections, pneumonia
    • Proteus: Urinary tract infections
    • Enterobacter: Urinary tract infections
    • Serratia: Urinary tract or infections

    Other Gram-Negative Bacteria

    • Legionella: Intracellular parasites; causes infections of the respiratory tract
    • Pseudomonas aeruginosa: Causes localized and systemic infections, important hospital acquired pathogen
    • Acinetobacter: Important nosocomial pathogens and cause hospital acquired infections or sepsis
    • Francisella tularensis: Causes tularemia (rabbit fever, deer fly fever)
    • Yersinia spp.: (Yersinia enterocolitica, Yersinia pestis)
      • Yersinia enterocolitica: Causes gastroenteritis and septicemia
      • Yersinia pestis: Causes plague

    Gram-negative Rods

    • Bacteroides: Causes peritonitis

    Overview

    • All gram-negative rods found in the GI tract of humans or animals.
    • Most are facultative anaerobes
    • Many produce LPS (endotoxin)
    • Contribute to gut microbiota
    • Transmission of pathogens often by fecal contamination.

    Clinical Significance

    • Many strains are associated with different types of disease.
    • Different diseases, such as meningitis or pneumonia, are caused by varied groups of gram-negative organisms.
    • Pathogens can cause infections of intestines and urinary tract, or respiratory systems

    Vaccines and Treatment

    • Available vaccines vary by particular pathogen
    • Treatment also varies with pathogen

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    Related Documents

    Gram Negative Bacteria PDF

    Description

    Explore the diverse world of gram-negative bacteria, including key genera such as Neisseria, Moraxella, and Helicobacter. This quiz covers their forms, infections caused, and characteristics, shedding light on their significance in health and disease.

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