Gram-Negative Bacteria and their Clinical Importance
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Questions and Answers

Which characteristic of Enterobacteriaceae is NOT mentioned in the text?

  • They have variable motility
  • They are cytochrome oxidase positive (correct)
  • They are bacilli and non-sporulated
  • They can reduce nitrate to nitrite

What is the main reason why non-fermenter gram-negative bacilli (BNF) are a relevant group?

  • They are incapable of reducing nitrate to nitrite
  • They cause severe, fatal infections, especially in the hospital environment (correct)
  • They have a higher frequency of isolation compared to Enterobacteriaceae
  • They are aerobic and can ferment sugars

Why are Gram-negative bacteria (GNB) considered a significant public health problem?

  • Because they primarily infect only healthy individuals
  • Due to their susceptibility to antibiotics
  • Because they are easy to manage and treat
  • As a result of their high resistance to antibiotics (correct)

What percentage of gram-negative isolates do Enterobacteriaceae account for according to the text?

<p>80% (B)</p> Signup and view all the answers

Which of the following is NOT a clinically pertinent gram-negative organism mentioned in the text?

<p>Clostridium difficile (D)</p> Signup and view all the answers

Why are patients infected with Gram-negative bacteria often placed in the intensive care unit (ICU)?

<p>Due to the high morbidity and mortality risk associated with GNB infections (B)</p> Signup and view all the answers

Which two large groups are responsible for most clinical isolates of Gram-negative bacteria?

<p>Enterobacteriaceae and non-fermenters (D)</p> Signup and view all the answers

How do Gram-negative bacteria differ from Gram-positive bacteria in terms of antibiotic resistance?

<p>Gram-positive bacteria are more susceptible to antibiotic resistance (C)</p> Signup and view all the answers

Which of the following diseases can be caused by Enterobacteriaceae?

<p>Urinary tract infections (A)</p> Signup and view all the answers

What is a distinguishing feature of non-fermenters mentioned in the text?

<p>They are capable of fermenting sugars (C)</p> Signup and view all the answers

Which of the following is a characteristic of Enterobacteriaceae mentioned in the text?

<p>Cytochrome oxidase positive (B)</p> Signup and view all the answers

What is a notable aspect of the antimicrobial sensitivity profile of non-fermenters?

<p>Intrinsic resistance due to specific gene mechanisms (C)</p> Signup and view all the answers

Which microorganism is NOT considered a non-fermenter according to the text?

<p>Klebsiella (A)</p> Signup and view all the answers

Why are Gram-negative bacteria considered a significant public health problem?

<p>Due to their high resistance to antibiotics (A)</p> Signup and view all the answers

Which group of gram-negative bacteria is responsible for most clinical isolates according to the text?

<p>Pseudomonas aeruginosa (A)</p> Signup and view all the answers

What is one of the clinically pertinent gram-negative organisms mentioned in the text?

<p>Escherichia coli (A)</p> Signup and view all the answers

What is the main difference between Enterobacteriaceae and non-fermenters as mentioned in the text?

<p>Their ability to ferment sugars (B)</p> Signup and view all the answers

Why do patients infected with Gram-negative bacteria often require intensive care unit (ICU) admission according to the text?

<p>Due to the need for constant monitoring and high risk of morbidity and mortality (C)</p> Signup and view all the answers

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