28 Questions
Which joint is most commonly affected during gout attacks?
Metatarsophalangeal (MTP) joint
What is podagra?
Gout of the big toe (foot)
What is the normal level of uric acid in the body?
< 6
What is the primary cause of gout?
Build up of uric acid crystals in the joints
What is the consequence of untreated re-occurring gout attacks?
Damage to the joints, tendons, and other tissues
Which DNA component breaks down to form uric acid, a key contributor to gout?
Guanine
Which of the following is NOT a risk factor for an acute gout attack?
Rapid lowering of uric acid levels
Which of the following medications is NOT likely to increase a patient’s risk of developing a gout attack?
Metformin 1000 mg PO BID
What percentage of US adults are affected by gout?
4%
What is the primary cause of hyperuricemia leading to gout?
Under-excretion of uric acid
What are the two primary methods of uric acid excretion from the body?
Kidney and gut
What is the most common gender affected by gout?
Men
Which of the following is a complication of uncontrolled gout?
Tophi
What is the peak age range for the onset of gout?
~50-60 years old
What is the serum uric acid level that defines hyperuricemia?
> 6.8 mg/dL
What is the main cause of osteoarthritis?
Deterioration of articular cartilage
What is the traditional description of osteoarthritis?
'Wear and tear' disease
What is the most preventable risk factor for developing osteoarthritis?
Obesity
What is the primary difference between osteoarthritis (OA) and rheumatoid arthritis (RA)?
OA is caused by an autoimmune response, while RA is due to wear and tear
What is the role of a pharmacist in managing osteoarthritis?
Advising on pharmacological and nonpharmacological therapies
Which of the following is NOT a risk factor for developing osteoarthritis?
Being a male over the age of 45
What is the primary role of a pharmacist in managing osteoarthritis?
Educating the patient and family members
Which of the following is NOT a location commonly affected by osteoarthritis?
Elbows
What is the hallmark symptom of osteoarthritis?
Pain in the joints
What is the main purpose of non-pharmacological management of osteoarthritis?
To educate the patient and minimize pain
Which of the following is a common misconception about osteoarthritis?
Knuckle cracking is a significant cause of osteoarthritis
What is the impact of 10% weight loss in women on the risk of developing osteoarthritis of the knees?
Reduces the risk by 50%
What is the role of physical stress (kneeling, squatting, lifting) in the development of osteoarthritis?
It increases the risk of developing osteoarthritis
Test your knowledge on identifying signs and symptoms of gout, assessing risk factors, nonpharmacological modifications to reduce gout flares, treatment options for acute gout attacks, and designing treatment plans for chronic gout.
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