14 Questions
Which hormone stimulates the Leydig's cells to synthesize testosterone in males?
Luteinizing hormone (LH)
What is the function of FSH in males according to the text?
Initiates and maintains spermatogenesis
Which cells does LH stimulate in females according to the given information?
Granulosa cells
What is sensitized by Gonadotropin-releasing hormone (GnRH) activation of the hypothalamic pituitary gonadal (HPG) axis?
Pituitary gland
Which hormone reduces growth hormone secretion and is used in the treatment of acromegaly?
Somatostatin
Which hormones are responsible for stimulating production of mature eggs in the ovaries?
FSH and LH
Which drugs are used to manipulate the actions of the hypothalamic pituitary gonadal axis?
Gonadotrophins
What hormone is used to confirm postmenopausal age in women?
FSH
What is the primary function of GnRH agonist in fertility treatment?
Induce release of gonadotrophins for mature follicles
Which hormone is not typically increased by the administration of GnRH agonist?
Thyroid stimulating hormone (TSH)
What is the role of gonadotropins in the reproductive system?
Facilitate ovulation and menstruation
Which hormones are part of the hypothalamic pituitary gonadal (HPG) axis?
FSH and LH
In which condition would GnRH agonist NOT be a suitable treatment?
Primary testicular failure
What is the primary function of Thyrotropes (thyrotrophs) in the anterior pituitary lobe?
Release thyroid stimulating hormone (TSH)
Study Notes
Hormone Regulation
- Luteinizing hormone (LH) stimulates Leydig's cells to synthesize testosterone in males.
- Follicle-stimulating hormone (FSH) stimulates sperm production in males.
Hormone Functions
- LH stimulates theca cells in females.
- GnRH (Gonadotropin-releasing hormone) activates the hypothalamic pituitary gonadal (HPG) axis, sensitizing the pituitary gland.
- Somatostatin reduces growth hormone secretion and is used to treat acromegaly.
Reproductive System
- FSH and LH stimulate the production of mature eggs in the ovaries.
- GnRH agonists are used to manipulate the hypothalamic pituitary gonadal axis.
Menopause and Fertility
- Follicle-stimulating hormone (FSH) is used to confirm postmenopausal age in women.
- The primary function of GnRH agonist in fertility treatment is to suppress gonadotropin release, allowing for controlled ovarian stimulation.
Hormone Interactions
- GnRH agonist increases LH and FSH production, but not insulin-like growth factor-1 (IGF-1).
- Gonadotropins (LH and FSH) play a crucial role in the reproductive system, stimulating gamete production.
- The hypothalamic pituitary gonadal (HPG) axis includes GnRH, LH, FSH, and sex steroids.
Pregnancy and Treatment
- GnRH agonist is not suitable for ovarian hyperstimulation syndrome treatment.
- Thyrotropes (thyrotrophs) in the anterior pituitary lobe stimulate thyroid-stimulating hormone (TSH) production, regulating thyroid function.
Test your knowledge on the role of gonadotropins in normal growth, sexual development, and reproduction, as well as their interaction with the hypothalamic pituitary gonadal (HPG) axis. Explore how periodic pulses of gonadotrophin-releasing hormone (GnRH) regulate the involved endocrine organs for a specific CNS response.
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