Podcast
Questions and Answers
Which enzyme catalyzes the conversion of glucose to glucose-6-phosphate in the preparatory phase of glycolysis?
Which enzyme catalyzes the conversion of glucose to glucose-6-phosphate in the preparatory phase of glycolysis?
- Phosphofructokinase-1
- Phosphohexose Isomerase
- Triose Phosphate Isomerase
- Hexokinase (correct)
What is the direct product of the aldolase reaction during glycolysis?
What is the direct product of the aldolase reaction during glycolysis?
- Glyceraldehyde-3-phosphate
- Dihydroxyacetone phosphate
- Fructose-6-phosphate
- Both glyceraldehyde-3-phosphate and dihydroxyacetone phosphate (correct)
Which of the following statements accurately describes the role of ATP in the preparatory phase of glycolysis?
Which of the following statements accurately describes the role of ATP in the preparatory phase of glycolysis?
- ATP is only used in the payoff phase not the preparation phase.
- ATP is consumed in two priming reactions to phosphorylate glucose and fructose-6-phosphate. (correct)
- ATP is produced during the conversion of glucose to fructose-6-phosphate.
- ATP is required for the isomerization of dihydroxyacetone phosphate to glyceraldehyde-3-phosphate.
What is the purpose of isomerizing dihydroxyacetone phosphate into glyceraldehyde-3-phosphate?
What is the purpose of isomerizing dihydroxyacetone phosphate into glyceraldehyde-3-phosphate?
Which enzyme catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate?
Which enzyme catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate?
Flashcards
Glucose Phosphorylation
Glucose Phosphorylation
The first step in glycolysis where glucose is converted to glucose-6-phosphate using ATP.
Isomerization
Isomerization
The conversion of glucose-6-phosphate to fructose-6-phosphate in glycolysis.
Phosphorylation
Phosphorylation
The addition of a phosphate group to fructose-6-phosphate to form fructose-1,6-bisphosphate.
Aldolase Reaction
Aldolase Reaction
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Triose Phosphate Isomerization
Triose Phosphate Isomerization
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Study Notes
Glycolysis - Preparatory Phase
- Glucose is the starting molecule
- The preparatory phase converts glucose into fructose 1,6-bisphosphate
- This process requires 2 ATP molecules
- The enzyme hexokinase phosphorylates glucose to glucose 6-phosphate
- Phosphohexose isomerase converts glucose 6-phosphate to fructose 6-phosphate
- Phosphofructokinase-1 phosphorylates fructose 6-phosphate to fructose 1,6-bisphosphate, consuming another ATP
- Aldolase is crucial in cleaving fructose 1,6-bisphosphate into two 3-carbon molecules
- The two 3-carbon molecules are dihydroxyacetone phosphate and glyceraldehyde 3-phosphate
- Triose phosphate isomerase converts dihydroxyacetone phosphate to glyceraldehyde 3-phosphate completing the preparatory phase
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