Glycolysis Preparatory Phase Quiz

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Questions and Answers

Which enzyme catalyzes the conversion of glucose to glucose-6-phosphate in the preparatory phase of glycolysis?

  • Phosphofructokinase-1
  • Phosphohexose Isomerase
  • Triose Phosphate Isomerase
  • Hexokinase (correct)

What is the direct product of the aldolase reaction during glycolysis?

  • Glyceraldehyde-3-phosphate
  • Dihydroxyacetone phosphate
  • Fructose-6-phosphate
  • Both glyceraldehyde-3-phosphate and dihydroxyacetone phosphate (correct)

Which of the following statements accurately describes the role of ATP in the preparatory phase of glycolysis?

  • ATP is only used in the payoff phase not the preparation phase.
  • ATP is consumed in two priming reactions to phosphorylate glucose and fructose-6-phosphate. (correct)
  • ATP is produced during the conversion of glucose to fructose-6-phosphate.
  • ATP is required for the isomerization of dihydroxyacetone phosphate to glyceraldehyde-3-phosphate.

What is the purpose of isomerizing dihydroxyacetone phosphate into glyceraldehyde-3-phosphate?

<p>To ensure both products from the aldolase reaction can proceed in the subsequent steps of glycolysis. (C)</p> Signup and view all the answers

Which enzyme catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate?

<p>Phosphofructokinase-1 (A)</p> Signup and view all the answers

Flashcards

Glucose Phosphorylation

The first step in glycolysis where glucose is converted to glucose-6-phosphate using ATP.

Isomerization

The conversion of glucose-6-phosphate to fructose-6-phosphate in glycolysis.

Phosphorylation

The addition of a phosphate group to fructose-6-phosphate to form fructose-1,6-bisphosphate.

Aldolase Reaction

The cleavage of fructose-1,6-bisphosphate into glyceraldehyde-3-phosphate and dihydroxyacetone phosphate.

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Triose Phosphate Isomerization

The conversion of dihydroxyacetone phosphate to glyceraldehyde-3-phosphate to ensure proper metabolic flow.

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Study Notes

Glycolysis - Preparatory Phase

  • Glucose is the starting molecule
  • The preparatory phase converts glucose into fructose 1,6-bisphosphate
  • This process requires 2 ATP molecules
  • The enzyme hexokinase phosphorylates glucose to glucose 6-phosphate
  • Phosphohexose isomerase converts glucose 6-phosphate to fructose 6-phosphate
  • Phosphofructokinase-1 phosphorylates fructose 6-phosphate to fructose 1,6-bisphosphate, consuming another ATP
  • Aldolase is crucial in cleaving fructose 1,6-bisphosphate into two 3-carbon molecules
  • The two 3-carbon molecules are dihydroxyacetone phosphate and glyceraldehyde 3-phosphate
  • Triose phosphate isomerase converts dihydroxyacetone phosphate to glyceraldehyde 3-phosphate completing the preparatory phase

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