18 Questions
What happens to glycolysis when ATP levels are high after a high carbohydrate intake?
Glycolysis is inhibited
What is the effect of insulin on PFK2?
It phosphorylates and activates PFK2
What is the function of PFK2 in the liver?
Convert fructose 6P to Fructose 2,6 bisP
What is the consequence of pyruvate kinase deficiency in RBCs?
Decreased oxygen unloading from Hb
What is the effect of glucagon on PFK2?
It dephosphorylates and deactivates PFK2
What is the result of high AMP levels in the cell?
Stimulation of glycolysis
Which of the following enzymes is inhibited by its product?
Hexokinase
What is the role of GLUT4 in skeletal muscles?
To transport glucose into the cell
What is the function of Glucokinase in liver cells?
To phosphorylate glucose using 1 ATP
What is the effect of AMP on Phosphofructokinase1 (PFK1)?
It activates PFK1
Which of the following is not a kinetic parameter of GLUT1 and GLUT3?
High Km value
What is the result of exercise on GLUT4 in muscles?
It opens in muscles and closes in adipose
What is the outcome when a long-term alcoholic patient with dehydration and thirst is infused with glucose (IV)?
It will cause severe harm to the patient
What is the function of the pyruvate dehydrogenase enzyme?
To require 5 different cofactors
What happens when citrate concentration increases in the citric acid cycle?
PFK1 enzyme is inhibited
What is the purpose of the electron shuttle in glycolysis?
To transport high-energy electrons
What is the outcome when oxygen is necessary to accept high-energy electrons?
Electrons move like an electric current
What is the product of the breakdown of one glucose molecule in glycolysis?
2 Pyruvate molecules
Learn about the process of glycolysis, how glucose enters cells through transporters GLUT1-4, and the role of insulin in this process. Explore the differences in glucose uptake in various cell types, including skeletal muscles and adipose tissue.
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