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Glycolysis and Glucose Transport

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Questions and Answers

What happens to glycolysis when ATP levels are high after a high carbohydrate intake?

Glycolysis is activated by PFK2

Glycolysis is inhibited (correct)

Glycolysis remains unchanged

Glycolysis is stimulated

What is the effect of insulin on PFK2?

It inhibits glycolysis

It dephosphorylates and deactivates PFK2

It has no effect on PFK2

It phosphorylates and activates PFK2 (correct)

What is the function of PFK2 in the liver?

Convert fructose 6P to Fructose 2,6 bisP (correct)

Inhibit glycolysis

Activate pyruvate kinase

Convert pyruvate to acetyl-CoA

What is the consequence of pyruvate kinase deficiency in RBCs?

Decreased oxygen unloading from Hb Signup and view all the answers

What is the effect of glucagon on PFK2?

It dephosphorylates and deactivates PFK2 Signup and view all the answers

What is the result of high AMP levels in the cell?

Stimulation of glycolysis Signup and view all the answers

Which of the following enzymes is inhibited by its product?

Hexokinase Signup and view all the answers

What is the role of GLUT4 in skeletal muscles?

To transport glucose into the cell Signup and view all the answers

What is the function of Glucokinase in liver cells?

To phosphorylate glucose using 1 ATP Signup and view all the answers

What is the effect of AMP on Phosphofructokinase1 (PFK1)?

It activates PFK1 Signup and view all the answers

Which of the following is not a kinetic parameter of GLUT1 and GLUT3?

High Km value Signup and view all the answers

What is the result of exercise on GLUT4 in muscles?

It opens in muscles and closes in adipose Signup and view all the answers

What is the outcome when a long-term alcoholic patient with dehydration and thirst is infused with glucose (IV)?

It will cause severe harm to the patient Signup and view all the answers

What is the function of the pyruvate dehydrogenase enzyme?

To require 5 different cofactors Signup and view all the answers

What happens when citrate concentration increases in the citric acid cycle?

PFK1 enzyme is inhibited Signup and view all the answers

What is the purpose of the electron shuttle in glycolysis?

To transport high-energy electrons Signup and view all the answers

What is the outcome when oxygen is necessary to accept high-energy electrons?

Electrons move like an electric current Signup and view all the answers

What is the product of the breakdown of one glucose molecule in glycolysis?

2 Pyruvate molecules Signup and view all the answers