Glycolysis and Glucose Transport

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Questions and Answers

What happens to glycolysis when ATP levels are high after a high carbohydrate intake?

  • Glycolysis is activated by PFK2
  • Glycolysis is inhibited (correct)
  • Glycolysis remains unchanged
  • Glycolysis is stimulated

What is the effect of insulin on PFK2?

  • It inhibits glycolysis
  • It dephosphorylates and deactivates PFK2
  • It has no effect on PFK2
  • It phosphorylates and activates PFK2 (correct)

What is the function of PFK2 in the liver?

  • Convert fructose 6P to Fructose 2,6 bisP (correct)
  • Inhibit glycolysis
  • Activate pyruvate kinase
  • Convert pyruvate to acetyl-CoA

What is the consequence of pyruvate kinase deficiency in RBCs?

<p>Decreased oxygen unloading from Hb (D)</p> Signup and view all the answers

What is the effect of glucagon on PFK2?

<p>It dephosphorylates and deactivates PFK2 (A)</p> Signup and view all the answers

What is the result of high AMP levels in the cell?

<p>Stimulation of glycolysis (C)</p> Signup and view all the answers

Which of the following enzymes is inhibited by its product?

<p>Hexokinase (C)</p> Signup and view all the answers

What is the role of GLUT4 in skeletal muscles?

<p>To transport glucose into the cell (B)</p> Signup and view all the answers

What is the function of Glucokinase in liver cells?

<p>To phosphorylate glucose using 1 ATP (C)</p> Signup and view all the answers

What is the effect of AMP on Phosphofructokinase1 (PFK1)?

<p>It activates PFK1 (C)</p> Signup and view all the answers

Which of the following is not a kinetic parameter of GLUT1 and GLUT3?

<p>High Km value (B)</p> Signup and view all the answers

What is the result of exercise on GLUT4 in muscles?

<p>It opens in muscles and closes in adipose (D)</p> Signup and view all the answers

What is the outcome when a long-term alcoholic patient with dehydration and thirst is infused with glucose (IV)?

<p>It will cause severe harm to the patient (A)</p> Signup and view all the answers

What is the function of the pyruvate dehydrogenase enzyme?

<p>To require 5 different cofactors (C)</p> Signup and view all the answers

What happens when citrate concentration increases in the citric acid cycle?

<p>PFK1 enzyme is inhibited (C)</p> Signup and view all the answers

What is the purpose of the electron shuttle in glycolysis?

<p>To transport high-energy electrons (B)</p> Signup and view all the answers

What is the outcome when oxygen is necessary to accept high-energy electrons?

<p>Electrons move like an electric current (D)</p> Signup and view all the answers

What is the product of the breakdown of one glucose molecule in glycolysis?

<p>2 Pyruvate molecules (D)</p> Signup and view all the answers

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