Glycolysis and Glucose Transport

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18 Questions

What happens to glycolysis when ATP levels are high after a high carbohydrate intake?

Glycolysis is inhibited

What is the effect of insulin on PFK2?

It phosphorylates and activates PFK2

What is the function of PFK2 in the liver?

Convert fructose 6P to Fructose 2,6 bisP

What is the consequence of pyruvate kinase deficiency in RBCs?

Decreased oxygen unloading from Hb

What is the effect of glucagon on PFK2?

It dephosphorylates and deactivates PFK2

What is the result of high AMP levels in the cell?

Stimulation of glycolysis

Which of the following enzymes is inhibited by its product?

Hexokinase

What is the role of GLUT4 in skeletal muscles?

To transport glucose into the cell

What is the function of Glucokinase in liver cells?

To phosphorylate glucose using 1 ATP

What is the effect of AMP on Phosphofructokinase1 (PFK1)?

It activates PFK1

Which of the following is not a kinetic parameter of GLUT1 and GLUT3?

High Km value

What is the result of exercise on GLUT4 in muscles?

It opens in muscles and closes in adipose

What is the outcome when a long-term alcoholic patient with dehydration and thirst is infused with glucose (IV)?

It will cause severe harm to the patient

What is the function of the pyruvate dehydrogenase enzyme?

To require 5 different cofactors

What happens when citrate concentration increases in the citric acid cycle?

PFK1 enzyme is inhibited

What is the purpose of the electron shuttle in glycolysis?

To transport high-energy electrons

What is the outcome when oxygen is necessary to accept high-energy electrons?

Electrons move like an electric current

What is the product of the breakdown of one glucose molecule in glycolysis?

2 Pyruvate molecules

Learn about the process of glycolysis, how glucose enters cells through transporters GLUT1-4, and the role of insulin in this process. Explore the differences in glucose uptake in various cell types, including skeletal muscles and adipose tissue.

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