Glycogenolysis Overview

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Questions and Answers

What is the end product of glycogenolysis after glucose-1-phosphate?

Fructose-1,6-bisphosphate
Pyruvate
Glucose-6-phosphate (correct)
Glycogen

Which hormone activates glycogen breakdown in the liver?

Cortisol
Insulin
Glucagon (correct)
Adrenaline

What inhibits the process of glycogenolysis?

Glucagon
Insulin (correct)
Cyclic AMP
Epinephrine

In which tissues does glycolysis primarily proceed after glycogenolysis?

<p>Liver and kidney (C)</p> Signup and view all the answers

From where are glucose molecules removed during glycogenolysis?

<p>From the end of the glycogen chain (A)</p> Signup and view all the answers

Flashcards

Glycogenolysis

The breakdown of glycogen into glucose. Glucose molecules are removed one by one from the end of the glycogen chain to yield glucose-1-phosphate.

What triggers glycogenolysis?

Glycogenolysis is activated by glucagon (in the liver) and epinephrine (in muscle).

What inhibits glycogenolysis?

Insulin inhibits glycogenolysis. Insulin signals the body to store glucose.

Glucose-1-phosphate

A molecule produced during glycogenolysis, a key intermediate in the process.

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Glucose-6-phosphate

A molecule formed from glucose-1-phosphate, further processed in glycolysis.

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Study Notes

Glycogenolysis

Glycogenolysis is the breakdown of glycogen into glucose
Glycogen is broken down into glucose
Glucose molecules are removed one at a time from the end of the glycogen chain. This yields glucose-1-phosphate.
Glycogenolysis is activated by glucagon (in the liver) and epinephrine (in the muscle)
Glycogenolysis is inhibited by insulin
Glucose-1-phosphate is converted to glucose-6-phosphate
Glucose-6-phosphate enters glycolysis (in liver and kidneys) to produce glucose.

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Description

This quiz covers the biochemical process of glycogenolysis, detailing how glycogen is broken down into glucose. Key mechanisms, including activation by glucagon and epinephrine, as well as the inhibiting role of insulin, are discussed. Understand the conversion of glucose-1-phosphate to glucose-6-phosphate and its entry into glycolysis.