10 Questions
What is the average chain length for glycogen?
12-14 glucose units per chain
What is the main function of liver glycogen?
Maintain glucose levels during fasting
What is the ratio of Pi:G1P at equilibrium during glycogenolysis?
1:4
What is the product of the reaction catalyzed by phosphorylase during glycogenolysis?
$Glucose-1-phosphate$
What are the two major tissues for glycogen storage?
Muscle and liver
What is the main function of muscle glycogen?
Provides the energy source for strenuous activity
What is the structure of glycogen?
Linear chains of a-1,4 linked glucose units with a-1,6 linkages forming a branched macromolecule
What is the product of the reaction catalyzed by phosphorylase during glycogenolysis?
$Glucose ext{-}1 ext{-}phosphate$
What is the average chain length for glycogen?
$10-12$ glucose units per chain
Which enzyme is responsible for breaking down the branches in glycogen during glycogenolysis?
$Debranching$ $enzyme$
Study Notes
Glycogen Structure and Function
- Glycogen has a highly branched structure, with an average chain length of 10-14 glucose residues.
- The two major tissues for glycogen storage are the liver and muscles.
Glycogenolysis
- The main function of liver glycogen is to regulate blood glucose levels.
- The main function of muscle glycogen is to provide energy for muscle contractions.
- During glycogenolysis, the enzyme phosphorylase catalyzes the reaction that breaks down glycogen to glucose-1-phosphate (G1P).
- The product of the reaction catalyzed by phosphorylase during glycogenolysis is glucose-1-phosphate (G1P).
- The enzyme responsible for breaking down the branches in glycogen during glycogenolysis is debranching enzyme.
- At equilibrium, the ratio of Pi:G1P is 1:1.
Test your knowledge of glycogen metabolism, including its structure, breakdown, synthesis, regulation of enzymes, and storage diseases. Explore the functions of glycogen as the storage form of glucose in eukaryotic cells, particularly in the liver and muscle tissues.
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