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Questions and Answers
Which enzyme is lacking in muscle that prevents glucose-1-phosphate from being available to other tissues?
Which enzyme is lacking in muscle that prevents glucose-1-phosphate from being available to other tissues?
- Glucose-6-phosphatase (correct)
- Glycogen synthase
- Glycogen phosphorylase
- Glucose-1-phosphatase
What is the major site of glucose consumption in the body?
What is the major site of glucose consumption in the body?
- Liver
- Brain (correct)
- Blood
- Skeletal muscle
Which type of glycosidic linkage is present at the branch points of glycogen?
Which type of glycosidic linkage is present at the branch points of glycogen?
- b-1-4
- b-1-6
- a-1-6 (correct)
- a-1-4
How much glycogen does the liver have under a well-fed state?
How much glycogen does the liver have under a well-fed state?
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What is the product of glycogenolysis in the liver?
What is the product of glycogenolysis in the liver?
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Study Notes
Enzyme Deficiency
- In muscle, the enzyme glucose-6-phosphatase is lacking, preventing glucose-1-phosphate from being available to other tissues.
Glucose Consumption
- The major site of glucose consumption in the body is the brain.
Glycogen Structure
- At the branch points of glycogen, an α-1,6 glycosidic linkage is present.
Liver Glycogen
- Under a well-fed state, the liver typically has around 5-10% of its mass as glycogen.
Glycogenolysis
- The product of glycogenolysis in the liver is glucose-6-phosphate.
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