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Questions and Answers
Which enzyme is responsible for bypassing the irreversible hexokinase reaction during glucose 6-phosphate hydrolysis?
Which enzyme is responsible for bypassing the irreversible hexokinase reaction during glucose 6-phosphate hydrolysis?
- Glucose 6-phosphatase (correct)
- Glucose 6-phosphate translocase
- Hexokinase
- Glycogen phosphorylase
Which two organs release free glucose from G-6-P?
Which two organs release free glucose from G-6-P?
- Liver and pancreas
- Liver and heart
- Kidney and pancreas
- Liver and kidney (correct)
What is the function of glucose 6-phosphate translocase?
What is the function of glucose 6-phosphate translocase?
- To transport G-6-P across the ER membrane (correct)
- To convert G-6-P to glucose
- To convert glucose to G-6-P
- To transport glucose across the ER membrane
Which enzyme is required for the final step of glycogen degradation?
Which enzyme is required for the final step of glycogen degradation?
What is Type Ia glycogen storage disease?
What is Type Ia glycogen storage disease?
What is the function of glucose 6-phosphate?
What is the function of glucose 6-phosphate?
Which two proteins are required for glucose 6-phosphate hydrolysis?
Which two proteins are required for glucose 6-phosphate hydrolysis?
Which cells contain glucose 6-phosphatase?
Which cells contain glucose 6-phosphatase?
What is the consequence of lack of glucose 6-phosphatase?
What is the consequence of lack of glucose 6-phosphatase?
Which enzyme is responsible for bypassing the irreversible hexokinase reaction during glucose 6-phosphate hydrolysis?
Which enzyme is responsible for bypassing the irreversible hexokinase reaction during glucose 6-phosphate hydrolysis?
Which two organs release free glucose from G-6-P?
Which two organs release free glucose from G-6-P?
What is the function of glucose 6-phosphate translocase?
What is the function of glucose 6-phosphate translocase?
Which enzyme is required for the final step of glycogen degradation?
Which enzyme is required for the final step of glycogen degradation?
What is Type Ia glycogen storage disease?
What is Type Ia glycogen storage disease?
What is the function of glucose 6-phosphate?
What is the function of glucose 6-phosphate?
Which two proteins are required for glucose 6-phosphate hydrolysis?
Which two proteins are required for glucose 6-phosphate hydrolysis?
Which cells contain glucose 6-phosphatase?
Which cells contain glucose 6-phosphatase?
What is the consequence of lack of glucose 6-phosphatase?
What is the consequence of lack of glucose 6-phosphatase?
Which step of glycogen degradation is glucose 6-phosphate involved in?
Which step of glycogen degradation is glucose 6-phosphate involved in?
Which enzyme is responsible for releasing free glucose from G-6-P in liver and kidney?
Which enzyme is responsible for releasing free glucose from G-6-P in liver and kidney?
Which two proteins are required for transporting G-6-P across the ER membrane and releasing free glucose in liver and kidney?
Which two proteins are required for transporting G-6-P across the ER membrane and releasing free glucose in liver and kidney?
Which organs in the body release free glucose from G-6-P?
Which organs in the body release free glucose from G-6-P?
What is the consequence of lack of glucose 6-phosphatase in Type Ia glycogen storage disease?
What is the consequence of lack of glucose 6-phosphatase in Type Ia glycogen storage disease?
Which step of glycogen degradation requires glucose 6-phosphate translocase and glucose 6-phosphatase?
Which step of glycogen degradation requires glucose 6-phosphate translocase and glucose 6-phosphatase?
Which reaction is bypassed by hydrolysis of glucose 6-phosphate by glucose 6-phosphatase?
Which reaction is bypassed by hydrolysis of glucose 6-phosphate by glucose 6-phosphatase?
Which two organs in the body have glucose 6-phosphatase?
Which two organs in the body have glucose 6-phosphatase?
What is Type Ia glycogen storage disease?
What is Type Ia glycogen storage disease?
Which enzyme is responsible for the first step in glycogen synthesis?
Which enzyme is responsible for the first step in glycogen synthesis?
Which two proteins are required for the final step of glycogen degradation?
Which two proteins are required for the final step of glycogen degradation?
Study Notes
Glucose 6-Phosphate Hydrolysis
- Glucose 6-phosphatase is the enzyme responsible for bypassing the irreversible hexokinase reaction during glucose 6-phosphate hydrolysis.
- Liver and kidney are the two organs that release free glucose from G-6-P.
- Glucose 6-phosphate translocase functions in transporting G-6-P across the ER membrane.
Glycogen Degradation
- Glucose 6-phosphatase is required for the final step of glycogen degradation.
- Glucose 6-phosphate translocase and glucose 6-phosphatase are needed for the final step of glycogen degradation.
Glycogen Storage Disease
- Type Ia glycogen storage disease is a disease caused by the lack of glucose 6-phosphatase.
- Consequences of lack of glucose 6-phosphatase include Type Ia glycogen storage disease.
Glucose 6-Phosphate Function
- Glucose 6-phosphate is involved in the step of glycogen degradation that releases free glucose.
- The function of glucose 6-phosphate is to release free glucose from G-6-P.
Proteins Required for Glucose 6-Phosphate Hydrolysis
- Glucose 6-phosphatase and glucose 6-phosphate translocase are the two proteins required for glucose 6-phosphate hydrolysis.
- Glucose 6-phosphatase and glucose 6-phosphate translocase are required for transporting G-6-P across the ER membrane and releasing free glucose in liver and kidney.
Cellular Location of Glucose 6-Phosphatase
- Glucose 6-phosphatase is found in liver and kidney cells.
Enzyme Function in Glycogen Synthesis
- Glucose 6-phosphate is not involved in glycogen synthesis, and the enzyme required for the first step in glycogen synthesis is not glucose 6-phosphatase.
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Description
Test your knowledge on glucose metabolism with this quiz! Learn about the hydrolysis of glucose 6-phosphate and the role of glucose 6-phosphatase in bypassing the irreversible hexokinase reaction. Discover which organs release free glucose from G-6-P and the proteins required for this process. Challenge yourself with these fascinating facts about glucose metabolism!