Glucose Metabolism Quiz
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Questions and Answers

Which enzyme is responsible for bypassing the irreversible hexokinase reaction during glucose 6-phosphate hydrolysis?

  • Glucose 6-phosphatase (correct)
  • Glucose 6-phosphate translocase
  • Hexokinase
  • Glycogen phosphorylase

Which two organs release free glucose from G-6-P?

  • Liver and pancreas
  • Liver and heart
  • Kidney and pancreas
  • Liver and kidney (correct)

What is the function of glucose 6-phosphate translocase?

  • To transport G-6-P across the ER membrane (correct)
  • To convert G-6-P to glucose
  • To convert glucose to G-6-P
  • To transport glucose across the ER membrane

Which enzyme is required for the final step of glycogen degradation?

<p>Glycogen phosphorylase (D)</p> Signup and view all the answers

What is Type Ia glycogen storage disease?

<p>Lack of glucose 6-phosphatase (C)</p> Signup and view all the answers

What is the function of glucose 6-phosphate?

<p>To bypass hexokinase reaction (D)</p> Signup and view all the answers

Which two proteins are required for glucose 6-phosphate hydrolysis?

<p>Glucose 6-phosphate translocase and glucose 6-phosphatase (D)</p> Signup and view all the answers

Which cells contain glucose 6-phosphatase?

<p>Gluconeogenic cells (A)</p> Signup and view all the answers

What is the consequence of lack of glucose 6-phosphatase?

<p>Severe fasting hypoglycemia (C)</p> Signup and view all the answers

Which enzyme is responsible for bypassing the irreversible hexokinase reaction during glucose 6-phosphate hydrolysis?

<p>Glucose 6-phosphatase (D)</p> Signup and view all the answers

Which two organs release free glucose from G-6-P?

<p>Liver and kidney (B)</p> Signup and view all the answers

What is the function of glucose 6-phosphate translocase?

<p>To transport G-6-P across the ER membrane (D)</p> Signup and view all the answers

Which enzyme is required for the final step of glycogen degradation?

<p>Glycogen phosphorylase (B)</p> Signup and view all the answers

What is Type Ia glycogen storage disease?

<p>Lack of glucose 6-phosphatase (B)</p> Signup and view all the answers

What is the function of glucose 6-phosphate?

<p>To bypass hexokinase reaction (D)</p> Signup and view all the answers

Which two proteins are required for glucose 6-phosphate hydrolysis?

<p>Glucose 6-phosphate translocase and glucose 6-phosphatase (B)</p> Signup and view all the answers

Which cells contain glucose 6-phosphatase?

<p>Gluconeogenic cells (C)</p> Signup and view all the answers

What is the consequence of lack of glucose 6-phosphatase?

<p>Severe fasting hypoglycemia (A)</p> Signup and view all the answers

Which step of glycogen degradation is glucose 6-phosphate involved in?

<p>None of the above (C)</p> Signup and view all the answers

Which enzyme is responsible for releasing free glucose from G-6-P in liver and kidney?

<p>Glucose 6-phosphatase (B)</p> Signup and view all the answers

Which two proteins are required for transporting G-6-P across the ER membrane and releasing free glucose in liver and kidney?

<p>Glucose 6-phosphate translocase and glucose 6-phosphatase (A)</p> Signup and view all the answers

Which organs in the body release free glucose from G-6-P?

<p>Liver and kidney (A)</p> Signup and view all the answers

What is the consequence of lack of glucose 6-phosphatase in Type Ia glycogen storage disease?

<p>Low blood glucose levels (A)</p> Signup and view all the answers

Which step of glycogen degradation requires glucose 6-phosphate translocase and glucose 6-phosphatase?

<p>Termination of glycogenolysis (B)</p> Signup and view all the answers

Which reaction is bypassed by hydrolysis of glucose 6-phosphate by glucose 6-phosphatase?

<p>Glycogen synthesis (D)</p> Signup and view all the answers

Which two organs in the body have glucose 6-phosphatase?

<p>Liver and kidney (C)</p> Signup and view all the answers

What is Type Ia glycogen storage disease?

<p>A disease caused by lack of glucose 6-phosphatase (A)</p> Signup and view all the answers

Which enzyme is responsible for the first step in glycogen synthesis?

<p>Hexokinase (B)</p> Signup and view all the answers

Which two proteins are required for the final step of glycogen degradation?

<p>Glucose 6-phosphate translocase and glucose 6-phosphatase (A)</p> Signup and view all the answers

Study Notes

Glucose 6-Phosphate Hydrolysis

  • Glucose 6-phosphatase is the enzyme responsible for bypassing the irreversible hexokinase reaction during glucose 6-phosphate hydrolysis.
  • Liver and kidney are the two organs that release free glucose from G-6-P.
  • Glucose 6-phosphate translocase functions in transporting G-6-P across the ER membrane.

Glycogen Degradation

  • Glucose 6-phosphatase is required for the final step of glycogen degradation.
  • Glucose 6-phosphate translocase and glucose 6-phosphatase are needed for the final step of glycogen degradation.

Glycogen Storage Disease

  • Type Ia glycogen storage disease is a disease caused by the lack of glucose 6-phosphatase.
  • Consequences of lack of glucose 6-phosphatase include Type Ia glycogen storage disease.

Glucose 6-Phosphate Function

  • Glucose 6-phosphate is involved in the step of glycogen degradation that releases free glucose.
  • The function of glucose 6-phosphate is to release free glucose from G-6-P.

Proteins Required for Glucose 6-Phosphate Hydrolysis

  • Glucose 6-phosphatase and glucose 6-phosphate translocase are the two proteins required for glucose 6-phosphate hydrolysis.
  • Glucose 6-phosphatase and glucose 6-phosphate translocase are required for transporting G-6-P across the ER membrane and releasing free glucose in liver and kidney.

Cellular Location of Glucose 6-Phosphatase

  • Glucose 6-phosphatase is found in liver and kidney cells.

Enzyme Function in Glycogen Synthesis

  • Glucose 6-phosphate is not involved in glycogen synthesis, and the enzyme required for the first step in glycogen synthesis is not glucose 6-phosphatase.

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Description

Test your knowledge on glucose metabolism with this quiz! Learn about the hydrolysis of glucose 6-phosphate and the role of glucose 6-phosphatase in bypassing the irreversible hexokinase reaction. Discover which organs release free glucose from G-6-P and the proteins required for this process. Challenge yourself with these fascinating facts about glucose metabolism!

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