19 Questions
Which step in gluconeogenesis is the most energy-demanding?
Phosphoenolpyruvate synthesis from pyruvate
What is the purpose of coupling decarboxylation with phosphoenolpyruvate synthesis from pyruvate?
To overcome an energetic barrier
What is the four-carbon compound that pyruvate must be carboxylated to before decarboxylation can happen?
Oxaloacetate
Which compound is a three-carbon compound in both glycolysis and gluconeogenesis?
Pyruvate
Which compound is not involved in gluconeogenesis?
Acetyl-CoA
Which step in gluconeogenesis requires the input of ATP?
Pyruvate carboxylation
Which enzyme catalyzes the conversion of fructose-1,6-bisphosphate to fructose-6-phosphate in gluconeogenesis?
Fructose-1,6-bisphosphatase
Which step in glycolysis is bypassed in gluconeogenesis?
Conversion of fructose-6-phosphate to fructose-1,6-bisphosphate
Which compound is a product of gluconeogenesis?
Glucose
Which step in gluconeogenesis is the most energy-demanding?
Phosphoenolpyruvate synthesis from pyruvate
What is the purpose of coupling decarboxylation with phosphoenolpyruvate synthesis from pyruvate?
To overcome an energetic barrier
What is the four-carbon compound that pyruvate must be carboxylated to before decarboxylation can happen?
Oxaloacetate
Which compound is a three-carbon compound in both glycolysis and gluconeogenesis?
Pyruvate
Which enzyme is not used in gluconeogenesis?
Pyruvate kinase
Which compound is not involved in gluconeogenesis?
Acetyl-CoA
Which step in gluconeogenesis requires the input of ATP?
Pyruvate carboxylation
Which enzyme catalyzes the conversion of fructose-1,6-bisphosphate to fructose-6-phosphate in gluconeogenesis?
Fructose-1,6-bisphosphatase
Which step in glycolysis is bypassed in gluconeogenesis?
Conversion of fructose-6-phosphate to fructose-1,6-bisphosphate
Which compound is a product of gluconeogenesis?
Glucose
Test your knowledge on the most energy-demanding step in gluconeogenesis with our quiz! Learn about the replacement of pyruvate kinase, phosphofructokinase 1, and hexokinase with energetically favorable reactions, and understand how decarboxylation helps overcome the high ∆G barrier in phosphoenolpyruvate synthesis. Challenge yourself with this quiz and improve your understanding of carbohydrate metabolism!
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