Gluconeogenesis Quiz
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Questions and Answers

Which step in gluconeogenesis is the most energy-demanding?

  • Hexokinase
  • Phosphofructokinase 1
  • Phosphoenolpyruvate synthesis from pyruvate (correct)
  • Pyruvate kinase

What is the purpose of coupling decarboxylation with phosphoenolpyruvate synthesis from pyruvate?

  • To increase the rate of the reaction
  • To reduce the amount of ATP needed
  • To overcome an energetic barrier (correct)
  • To produce energy

What is the four-carbon compound that pyruvate must be carboxylated to before decarboxylation can happen?

  • Succinate
  • Oxaloacetate (correct)
  • Glucose
  • Fructose

Which compound is a three-carbon compound in both glycolysis and gluconeogenesis?

<p>Pyruvate (C)</p> Signup and view all the answers

Which compound is not involved in gluconeogenesis?

<p>Acetyl-CoA (C)</p> Signup and view all the answers

Which step in gluconeogenesis requires the input of ATP?

<p>Pyruvate carboxylation (C)</p> Signup and view all the answers

Which enzyme catalyzes the conversion of fructose-1,6-bisphosphate to fructose-6-phosphate in gluconeogenesis?

<p>Fructose-1,6-bisphosphatase (A)</p> Signup and view all the answers

Which step in glycolysis is bypassed in gluconeogenesis?

<p>Conversion of fructose-6-phosphate to fructose-1,6-bisphosphate (D)</p> Signup and view all the answers

Which compound is a product of gluconeogenesis?

<p>Glucose (C)</p> Signup and view all the answers

Which step in gluconeogenesis is the most energy-demanding?

<p>Phosphoenolpyruvate synthesis from pyruvate (B)</p> Signup and view all the answers

What is the purpose of coupling decarboxylation with phosphoenolpyruvate synthesis from pyruvate?

<p>To overcome an energetic barrier (B)</p> Signup and view all the answers

What is the four-carbon compound that pyruvate must be carboxylated to before decarboxylation can happen?

<p>Oxaloacetate (A)</p> Signup and view all the answers

Which compound is a three-carbon compound in both glycolysis and gluconeogenesis?

<p>Pyruvate (B)</p> Signup and view all the answers

Which enzyme is not used in gluconeogenesis?

<p>Pyruvate kinase (B)</p> Signup and view all the answers

Which compound is not involved in gluconeogenesis?

<p>Acetyl-CoA (A)</p> Signup and view all the answers

Which step in gluconeogenesis requires the input of ATP?

<p>Pyruvate carboxylation (C)</p> Signup and view all the answers

Which enzyme catalyzes the conversion of fructose-1,6-bisphosphate to fructose-6-phosphate in gluconeogenesis?

<p>Fructose-1,6-bisphosphatase (A)</p> Signup and view all the answers

Which step in glycolysis is bypassed in gluconeogenesis?

<p>Conversion of fructose-6-phosphate to fructose-1,6-bisphosphate (C)</p> Signup and view all the answers

Which compound is a product of gluconeogenesis?

<p>Glucose (C)</p> Signup and view all the answers

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