27 Questions
Where does Gluconeogenesis primarily occur?
In the liver and kidney.
What is the main purpose of Gluconeogenesis?
To synthesize glucose from non-carbohydrate precursors.
When is Gluconeogenesis particularly important?
During times of fasting.
What is the coenzyme involved in Reaction 1a of Gluconeogenesis?
Biotin.
Which enzyme is responsible for Reaction 1b of Gluconeogenesis?
Phosphoenolpyruvate carboxykinase.
Which glycolytic intermediate continues through the reversible reactions of glycolysis in Gluconeogenesis?
Phosphoenolpyruvate.
What is the enzyme responsible for Reaction 9 of Gluconeogenesis?
Fructose 1,6-bisphosphatase.
What is the enzyme responsible for Reaction 10 of Gluconeogenesis?
Phosphoglucose isomerase.
What is the purpose of Bypass reaction 3 in Gluconeogenesis?
To convert glucose-6-phosphate into glucose.
Which of the following is a product of anaerobic glycolysis?
Lactate
What happens to lactate in the liver?
It is converted to glucose
Which amino acids are considered glucogenic?
Alanine and glutamine
What enzyme is involved in the conversion of alanine to pyruvate?
Alanine Transaminase (ALT)
What is the coenzyme required for the transamination reaction?
Pyridoxal phosphate (PLP)
Which shuttle system is used when the starting substrate is alanine?
Malate shuttle
What happens to oxaloacetate in the malate shuttle?
It is converted to phosphoenolpyruvate (PEP)
What happens to lactate in the cytosol in the lactate shuttle?
It is converted to pyruvate
Where does gluconeogenesis begin in the cell?
Mitochondria
Why can't oxaloacetate cross the inner mitochondrial membrane?
It is charged
Which enzymes converts Lactate to Pyruvate?
LDH in liver cytosol
The cori cycle outlines the production and recycling of...
Lactate
The cori cycle can occur in a red blood cell
True
Glycerol can enter the gluconeogenesis pathway by being converted to...
ALT uses PLP as a coenzyme, which is derived from..
Vitamin B6
Oxaloacetate is converted to Malate by...
Pyruvate is converted to oxaloacetate by...
Pyruvate Carboxylase
PEP Carboxykinase converts...
Oxaloacetate to PEP
Test your knowledge on gluconeogenesis with this quiz! Learn about the synthesis of glucose from non-carbohydrate precursors and understand how it differs from glycolysis. Challenge your understanding of this important metabolic pathway and determine if gluconeogenesis is simply a reversal of glycolysis.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
