11 Questions
What is the primary human glucocorticoid?
Cortisol
How do glucocorticoids mainly promote normal metabolism?
Favor gluconeogenesis and stimulate protein catabolism
What is the primary mechanism by which glucocorticoids increase resistance to stress?
Raising plasma glucose levels
What effect do glucocorticoids have on blood cell levels in plasma?
Decrease eosinophils, basophils, monocytes, lymphocytes, and increase hemoglobin, erythrocytes, platelets
What is the most important therapeutic property of glucocorticoids?
Potent anti-inflammatory and immunosuppressive activities
Which type of corticoid helps control fluid status and electrolyte concentrations?
Mineralocorticoids
Which cellular component do corticosteroids bind to in order to enter the nucleus?
Cytosolic receptors
What type of elements do steroid-receptor complexes bind to in order to alter gene expression?
Glucocorticoid response elements (GREs)
Which synthetic glucocorticoid is considered intermediate-acting?
Betamethasone dipropionate
What is the primary natural glucocorticoid in humans?
Cortisol (hydrocortisone)
In which condition is Fludrocortisone acetate used due to its aldosterone-like activity?
Addison's disease
Test your knowledge on the effects of cortisol, the principal human glucocorticoid. Learn about how glucocorticoids promote normal metabolism, increase resistance to stress, and have diverse effects in the body.
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