16 Questions
What is the typical range of circulating glucagon concentrations in the normal fasting state?
Below 20 pmol/L
What is the role of basal glucagon secretion in the fasted state?
To balance the effect of basal insulin secretion
How do circulating glucagon levels change during hypoglycemia?
Increase dramatically up to 3-4 times basal levels
What does the graph represent on the left side?
Plasma glucose levels during different glycemic states
What do the dark blue diamonds on the left side of the graph represent?
Hypoglycemia
How do glucagon levels change during hyperglycemia?
Decrease to very low levels
What do the light blue circles on the left side of the graph represent?
Euglycemia
What is the relationship between glucagon and insulin during euglycemia?
Glucagon and insulin levels are balanced
Glucagon concentration in the circulation is measured in the nanomolar range.
False
During hyperglycemia, glucagon secretion levels are high.
False
Basal insulin secretion results in a steady-state between glucose uptake and exogenous glucose production in the fasted state.
False
Circulating glucagon levels decrease during exercise.
False
Plasma concentrations of glucagon during fasting are above 20 pmol/L.
False
The glucagon to insulin ratio decreases during hypoglycemia.
False
During euglycemia, basal levels of glucagon are secreted.
True
In a normal state, circulating glucagon concentrations are measured in the femtomolar range.
False
Test your knowledge on normal circulating glucagon concentrations and its role in balancing insulin secretion. Learn about the stable blood glucose concentration in the fasted state.
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