Glucagon Concentration in Circulation Quiz
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Questions and Answers

What is the typical range of circulating glucagon concentrations in the normal fasting state?

  • Below 20 pmol/L (correct)
  • Between 40-60 pmol/L
  • Between 20-40 pmol/L
  • Above 60 pmol/L
  • What is the role of basal glucagon secretion in the fasted state?

  • To stimulate gluconeogenesis
  • To increase glucose uptake
  • To lower blood glucose levels
  • To balance the effect of basal insulin secretion (correct)
  • How do circulating glucagon levels change during hypoglycemia?

  • Decrease to undetectable levels
  • Decrease slightly
  • Remain unchanged
  • Increase dramatically up to 3-4 times basal levels (correct)
  • What does the graph represent on the left side?

    <p>Plasma glucose levels during different glycemic states</p> Signup and view all the answers

    What do the dark blue diamonds on the left side of the graph represent?

    <p>Hypoglycemia</p> Signup and view all the answers

    How do glucagon levels change during hyperglycemia?

    <p>Decrease to very low levels</p> Signup and view all the answers

    What do the light blue circles on the left side of the graph represent?

    <p>Euglycemia</p> Signup and view all the answers

    What is the relationship between glucagon and insulin during euglycemia?

    <p>Glucagon and insulin levels are balanced</p> Signup and view all the answers

    Glucagon concentration in the circulation is measured in the nanomolar range.

    <p>False</p> Signup and view all the answers

    During hyperglycemia, glucagon secretion levels are high.

    <p>False</p> Signup and view all the answers

    Basal insulin secretion results in a steady-state between glucose uptake and exogenous glucose production in the fasted state.

    <p>False</p> Signup and view all the answers

    Circulating glucagon levels decrease during exercise.

    <p>False</p> Signup and view all the answers

    Plasma concentrations of glucagon during fasting are above 20 pmol/L.

    <p>False</p> Signup and view all the answers

    The glucagon to insulin ratio decreases during hypoglycemia.

    <p>False</p> Signup and view all the answers

    During euglycemia, basal levels of glucagon are secreted.

    <p>True</p> Signup and view all the answers

    In a normal state, circulating glucagon concentrations are measured in the femtomolar range.

    <p>False</p> Signup and view all the answers

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