Glucagon Concentration in Circulation Quiz

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IndustriousClavichord
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16 Questions

What is the typical range of circulating glucagon concentrations in the normal fasting state?

Below 20 pmol/L

What is the role of basal glucagon secretion in the fasted state?

To balance the effect of basal insulin secretion

How do circulating glucagon levels change during hypoglycemia?

Increase dramatically up to 3-4 times basal levels

What does the graph represent on the left side?

Plasma glucose levels during different glycemic states

What do the dark blue diamonds on the left side of the graph represent?

Hypoglycemia

How do glucagon levels change during hyperglycemia?

Decrease to very low levels

What do the light blue circles on the left side of the graph represent?

Euglycemia

What is the relationship between glucagon and insulin during euglycemia?

Glucagon and insulin levels are balanced

Glucagon concentration in the circulation is measured in the nanomolar range.

False

During hyperglycemia, glucagon secretion levels are high.

False

Basal insulin secretion results in a steady-state between glucose uptake and exogenous glucose production in the fasted state.

False

Circulating glucagon levels decrease during exercise.

False

Plasma concentrations of glucagon during fasting are above 20 pmol/L.

False

The glucagon to insulin ratio decreases during hypoglycemia.

False

During euglycemia, basal levels of glucagon are secreted.

True

In a normal state, circulating glucagon concentrations are measured in the femtomolar range.

False

Test your knowledge on normal circulating glucagon concentrations and its role in balancing insulin secretion. Learn about the stable blood glucose concentration in the fasted state.

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