Podcast
Questions and Answers
What is the typical range of circulating glucagon concentrations in the normal fasting state?
What is the typical range of circulating glucagon concentrations in the normal fasting state?
- Below 20 pmol/L (correct)
- Between 40-60 pmol/L
- Between 20-40 pmol/L
- Above 60 pmol/L
What is the role of basal glucagon secretion in the fasted state?
What is the role of basal glucagon secretion in the fasted state?
- To stimulate gluconeogenesis
- To increase glucose uptake
- To lower blood glucose levels
- To balance the effect of basal insulin secretion (correct)
How do circulating glucagon levels change during hypoglycemia?
How do circulating glucagon levels change during hypoglycemia?
- Decrease to undetectable levels
- Decrease slightly
- Remain unchanged
- Increase dramatically up to 3-4 times basal levels (correct)
What does the graph represent on the left side?
What does the graph represent on the left side?
What do the dark blue diamonds on the left side of the graph represent?
What do the dark blue diamonds on the left side of the graph represent?
How do glucagon levels change during hyperglycemia?
How do glucagon levels change during hyperglycemia?
What do the light blue circles on the left side of the graph represent?
What do the light blue circles on the left side of the graph represent?
What is the relationship between glucagon and insulin during euglycemia?
What is the relationship between glucagon and insulin during euglycemia?
Glucagon concentration in the circulation is measured in the nanomolar range.
Glucagon concentration in the circulation is measured in the nanomolar range.
During hyperglycemia, glucagon secretion levels are high.
During hyperglycemia, glucagon secretion levels are high.
Basal insulin secretion results in a steady-state between glucose uptake and exogenous glucose production in the fasted state.
Basal insulin secretion results in a steady-state between glucose uptake and exogenous glucose production in the fasted state.
Circulating glucagon levels decrease during exercise.
Circulating glucagon levels decrease during exercise.
Plasma concentrations of glucagon during fasting are above 20 pmol/L.
Plasma concentrations of glucagon during fasting are above 20 pmol/L.
The glucagon to insulin ratio decreases during hypoglycemia.
The glucagon to insulin ratio decreases during hypoglycemia.
During euglycemia, basal levels of glucagon are secreted.
During euglycemia, basal levels of glucagon are secreted.
In a normal state, circulating glucagon concentrations are measured in the femtomolar range.
In a normal state, circulating glucagon concentrations are measured in the femtomolar range.
