Glimepiride Flashcards

Questions and Answers

What is the brand name of Glimepiride?

Amaryl (correct)

Metformin

Glyburide

Diabeta

What is the generic name of Amaryl?

Glimepiride

What are the indications for Glimepiride?

As an adjunct to diet and exercise to lower blood glucose in patients with Type II diabetes mellitus.

What is the starting dose for Glimepiride?

1-2 mg daily Signup and view all the answers

The usual maintenance dose of Glimepiride is ______.

1-4 mg daily Signup and view all the answers

What is the maximum dose of Glimepiride?

8 mg daily Signup and view all the answers

What strengths of Glimepiride are available?

1 mg, 2 mg, 4 mg tablets Signup and view all the answers

What medication class does Glimepiride belong to?

Antidiabetic (Sulfonylureas) Signup and view all the answers

What is the mechanism of action of Glimepiride?

Stimulates insulin release from beta cells and may increase sensitivity of peripheral tissues to insulin. Signup and view all the answers

There is evidence of significant drug interactions with Glimepiride.

False Signup and view all the answers

Match the following side effects of Glimepiride:

Dizziness = Side effect Asthenia = Side effect Headache = Side effect Nausea = Side effect None above 10% = Side effect Signup and view all the answers

Match the contraindications for Glimepiride:

Diabetic ketoacidosis = Contraindication Cardiovascular disease = Contraindication Nursing mothers = Contraindication Signup and view all the answers

What should patients do if they miss a dose of Glimepiride?

Take it as soon as possible, or skip it if closer to the next dose. Signup and view all the answers

Patients should be aware of signs of hypoglycemia while taking Glimepiride.

True Signup and view all the answers

Study Notes

Glimepiride Overview

Brand name: Amaryl
Generic name: Glimepiride

Indications

Used as an adjunct to diet and exercise for managing blood glucose
Effective for patients with non-insulin dependent (Type II) diabetes where glucose levels can't be controlled with diet and exercise alone

Dosing

Initial dosing starts at 1-2 mg daily, taken with breakfast or the first main meal
Maintenance dose typically between 1-4 mg daily
Maximum allowable dose is 8 mg daily

Available Strengths

Tablets available in 1 mg, 2 mg, and 4 mg dosages

Medication Class

Classified as an antidiabetic medication belonging to the sulfonylureas family

Pharmacology

Works by stimulating insulin release from pancreatic beta cells
May enhance insulin sensitivity in peripheral tissues

Drug Interactions

No significant drug interactions have been documented

Side Effects

Common side effects include dizziness, asthenia, headache, and nausea
None of the side effects occur in more than 10% of patients

Contraindications

Not suitable for patients with diabetic ketoacidosis or associated coma
Caution advised in patients with cardiovascular disease due to increased mortality risk
Contraindicated in nursing mothers

Patient Counseling Information

Store in a cool, dry place away from sunlight and children
For missed doses, take as soon as remembered, but skip if close to the next scheduled dose; avoid doubling
Contact healthcare provider if severe or persistent side effects occur
Take with breakfast or the first main meal for optimal absorption
Adherence to prescribed diet is crucial for effectiveness
Limit alcohol consumption to avoid complications
Educate patients on signs of hypoglycemia such as sweating, tremor, blurred vision, weakness, hunger, and confusion; treat with oral glucose or seek medical advice if experiencing multiple symptoms

Description

Test your knowledge of Glimepiride with these flashcards. Learn key terms, definitions, indications, and dosing for this medication used to treat Type II diabetes. Perfect for students and healthcare professionals alike!