Questions and Answers
What is the generic name for Amaryl?
What is the pregnancy category for Glimepiride?
C
Which of the following is a dosage form of Glimepiride?
The maximum dosage of Glimepiride is ______ mg per day.
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Which of the following is NOT a side effect of Glimepiride?
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What is a contraindication for using Glimepiride?
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What should patients avoid while taking Glimepiride?
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Glimepiride is classified as a ______.
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Which blood tests should be monitored in patients on Glimepiride?
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Study Notes
Glimepiride (Amaryl) Overview
- Generic name: Glimepiride
- Brand name: Amaryl
- Class: Antidiabetic medication; belongs to sulfonylureas, which are hormones and synthetic substitutes.
Pregnancy and Dosage Information
- Pregnancy Category: C, implying potential risk; use cautiously.
- Available Dosage Forms: Tablets of 1 mg, 2 mg, and 4 mg.
- Adult Dosage: Initial dose is 1-2 mg orally once daily with breakfast or the first main meal; may be adjusted to 1-4 mg daily, with a maximum of 8 mg per day.
Side and Adverse Effects
- Common Side Effects: Flushing, photosensitivity, and alcohol intolerance.
- Gastrointestinal Distress: Symptoms include nausea, diarrhea, constipation, and jaundice.
- Hematologic Issues: Risks include leukopenia, thrombocytopenia, and agranulocytosis.
- Metabolic Concerns: May cause hypoglycemia, dilutional hyponatremia, and water intoxication.
- CNS Effects: Drowsiness, muscle cramps, weakness, and paresthesias.
- Skin Reactions: Rash and itching can occur.
Contraindications and Precautions
- Contraindications include hypersensitivity to glimepiride, diabetic ketoacidosis, and use during pregnancy and lactation. Not for nondiabetic patients with renal glycosuria.
- Precautions: Previous hypersensitivity to sulfonylureas, sulfonamides, or thiazide diuretics increase risk. Caution in those prone to hypoglycemia or with conditions like renal impairment or severe infections.
Nursing and Monitoring Considerations
- Routine Lab Tests: Regular monitoring of fasting, postprandial blood glucose, and urinary glucose levels.
- Glycosylated Hemoglobin: Should be monitored every 3-6 months.
- Long-term Monitoring: Check liver function tests, serum osmolarity, serum sodium, and complete blood count periodically.
- Hypoglycemia Risk: Close monitoring is necessary, especially when used with other medications that may enhance hypoglycemic effects.
Client Education
- Missed Dose: Take as soon as possible unless close to the next dose; never double up.
- Alcohol and OTC Drugs: Avoid without physician's approval.
- Sun Protection: Use sunscreen and avoid sunlamps.
- Awareness: Educate on adverse reactions and potential drug interactions.
- Breastfeeding: Avoid while taking glimepiride.
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Description
Test your knowledge on Glimepiride, also known as Amaryl, through these informative flashcards. Each card covers essential details such as generic names, classifications, and dosage information. Perfect for students or healthcare professionals looking to strengthen their understanding of this antidiabetic medication.
