Podcast
Questions and Answers
What is the peak incidence age for giant cell arteritis?
What is the peak incidence age for giant cell arteritis?
- 50 years
- 60 years
- 70 years (correct)
- 40 years
Which population group is predisposed to giant cell arteritis?
Which population group is predisposed to giant cell arteritis?
- Young adults
- Children
- Individuals of Northern European ancestry (correct)
- Males
What genetic background is associated with the pathogenesis of giant cell arteritis?
What genetic background is associated with the pathogenesis of giant cell arteritis?
- HLA.DRB1*04:04 only
- HLA.DRB1*04:04, HLA-DQA1*03:01, and HLA-DQA1*03:02 (correct)
- HLA-DQA1*03:02 only
- HLA-DQA1*03:01 only
Which arteries are mainly involved in giant cell arteritis?
Which arteries are mainly involved in giant cell arteritis?
What is the initial step in the pathogenesis of giant cell arteritis?
What is the initial step in the pathogenesis of giant cell arteritis?
In which other disease are dendritic cells involved in the infection?
In which other disease are dendritic cells involved in the infection?
What is the main cytokine of Th1 cells?
What is the main cytokine of Th1 cells?
What is the main hallmark of Th17 cells?
What is the main hallmark of Th17 cells?
What is the greatest risk factor for developing GCA?
What is the greatest risk factor for developing GCA?
What happens when a T cell and an antigen-presenting cell interact?
What happens when a T cell and an antigen-presenting cell interact?
What do GM-CSF, IL-17A, and IL-1beta contribute to in the inflammatory milieu?
What do GM-CSF, IL-17A, and IL-1beta contribute to in the inflammatory milieu?
What type of immune cell can change their behavior in GCA lesions?
What type of immune cell can change their behavior in GCA lesions?
What leads to intimal hyperplasia and arterial occlusion in GCA?
What leads to intimal hyperplasia and arterial occlusion in GCA?
What is the lifetime risk of developing GCA in men in the United States?
What is the lifetime risk of developing GCA in men in the United States?
What is the main function of activated macrophages in GCA lesions?
What is the main function of activated macrophages in GCA lesions?
What is the main role of DCs when enabled to process and present antigens?
What is the main role of DCs when enabled to process and present antigens?
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