GI System and Accessory Organs Quiz

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Questions and Answers

What is the primary function of trypsin and chymotrypsin?

  • Break down lipids
  • Break down proteins (correct)
  • Stimulate insulin secretion
  • Break down starches

Which organs synthesize and secrete amylase?

  • Liver, gallbladder, pancreas
  • Stomach, small intestine, pancreas
  • Gallbladder, stomach, liver
  • Salivary glands, pancreas, colon (correct)

What is the role of the gallbladder in digestion?

  • Secretes digestive enzymes
  • Produces bile
  • Stores and concentrates bile (correct)
  • Absorbs nutrients from food

What substance is released from the S cells of the duodenal mucosa when the pH is low?

<p>Secretin (D)</p> Signup and view all the answers

What effect does cholecystokinin (CCK) have on gastric emptying?

<p>Inhibits gastric emptying (D)</p> Signup and view all the answers

Which anatomical feature is used to define the upper and lower gastrointestinal bleed?

<p>Ligament of Treitz (A)</p> Signup and view all the answers

In which part of the digestive tract is most protein digestion initiated?

<p>Stomach (D)</p> Signup and view all the answers

What is the major function of lipase in digestion?

<p>Digests triglycerides into free fatty acids (B)</p> Signup and view all the answers

What is the difference between delirium and dementia in terms of onset?

<p>Dementia has a gradual onset, while delirium has a sudden onset. (A)</p> Signup and view all the answers

Which type of alterations can indicate a state of consciousness disturbance?

<p>Metabolic alterations related to electrolyte imbalances. (B)</p> Signup and view all the answers

What does an EEG reveal in cases of delirium?

<p>Abnormally slow rhythm. (C)</p> Signup and view all the answers

What condition is associated with the presence of beta-amyloid plaques?

<p>Dementia. (C)</p> Signup and view all the answers

What is the primary cause of acute cholecystitis?

<p>Gallstones obstruction (C)</p> Signup and view all the answers

Which symptom is indicative of acute cholecystitis?

<p>RUQ pain radiating to the right shoulder (C)</p> Signup and view all the answers

What is the maximum daily dose of acetaminophen recommended to avoid toxicity?

<p>4 grams (A)</p> Signup and view all the answers

Which medication is used to replenish glutathione stores in acetaminophen toxicity?

<p>N-Acetylcysteine (A)</p> Signup and view all the answers

Which condition is most commonly associated with chronic liver disease?

<p>Wilson's disease (B)</p> Signup and view all the answers

What can lead to the development of spontaneous bacterial peritonitis in liver disease?

<p>Portal hypertension (C)</p> Signup and view all the answers

What symptom arises due to the accumulation of ammonia in chronic liver disease?

<p>Confusion and decreased level of consciousness (D)</p> Signup and view all the answers

What happens when there is damage to an upper motor neuron?

<p>It results in spastic paralysis. (B)</p> Signup and view all the answers

Which system is specifically responsible for coordinating visceral responses during stress?

<p>Sympathetic Nervous System (C)</p> Signup and view all the answers

Bile duct obstruction in chronic pancreatitis is generally considered to be:

<p>Less common than pancreatic duct obstruction (D)</p> Signup and view all the answers

Which condition is characterized by hyperbilirubinemia and reduced coagulopathy?

<p>Chronic liver disease (B)</p> Signup and view all the answers

What is a key function of the parasympathetic nervous system?

<p>Enhances digestive activity during rest. (B)</p> Signup and view all the answers

What is the likely cause of caput medusae in patients with chronic liver disease?

<p>Increased pressure in hepatic veins (C)</p> Signup and view all the answers

What role do afferent nerve fibers play in the autonomic nervous system?

<p>They carry sensory impulses to the CNS. (C)</p> Signup and view all the answers

What does activation of Alpha 1 receptors lead to?

<p>Increased peripheral resistance. (C)</p> Signup and view all the answers

Which of the following is NOT a function of Beta 2 receptors?

<p>Increased blood pressure. (C)</p> Signup and view all the answers

Which neurotransmitter is primarily associated with stimulating Alpha 1 and Beta receptors?

<p>Norepinephrine (A)</p> Signup and view all the answers

How does epinephrine differ from norepinephrine in its action?

<p>It has a stronger effect on all types of receptors. (D)</p> Signup and view all the answers

Which type of hormones primarily attach to cytoplasmic receptors?

<p>Lipid soluble hormones (C)</p> Signup and view all the answers

What is the main function of the hypothalamus in relation to the endocrine system?

<p>To link the nervous and endocrine systems (A)</p> Signup and view all the answers

Which hormone is primarily released by the anterior pituitary in response to corticotropin releasing hormone?

<p>Adrenocorticotropic hormone (D)</p> Signup and view all the answers

Which receptor type is NOT associated with water soluble hormones?

<p>Cytoplasmic receptors (B)</p> Signup and view all the answers

What key hormone released by the anterior pituitary is responsible for stimulating milk production?

<p>Prolactin (D)</p> Signup and view all the answers

What is the primary purpose of setting an intubated patient to hyperventilation?

<p>To reduce CO2 levels and decrease cerebral artery dilation (A)</p> Signup and view all the answers

What is the diameter of the spinal cord compared to?

<p>The diameter of a human finger (C)</p> Signup and view all the answers

Which type of nerve fibers primarily carry sensory information to the central nervous system?

<p>Afferent nerve fibers (A)</p> Signup and view all the answers

What is the function of the dorsal column tracts?

<p>To transmit highly localized sensations while ascending the spinal cord (C)</p> Signup and view all the answers

What is the result of damage to lower motor neurons (LMN) innervating a specific muscle?

<p>Flaccid paralysis of that muscle (C)</p> Signup and view all the answers

Which statement about the spinothalamic tracts is true?

<p>They are responsible for transmitting less localized sensations and cross immediately to the opposite side. (D)</p> Signup and view all the answers

What important role do upper motor neurons play in the nervous system?

<p>They are responsible for reflexes and direct voluntary movement. (A)</p> Signup and view all the answers

What is the central canal of the spinal cord continuous with?

<p>The ventricular system of the brain (C)</p> Signup and view all the answers

Which function is primarily associated with the liver in the GI system?

<p>Production of clotting factors (A)</p> Signup and view all the answers

What is the role of Kupffer cells in the liver?

<p>Act as specialized macrophages (A)</p> Signup and view all the answers

Which of the following is NOT a major function of the GI system?

<p>Neurological signaling (A)</p> Signup and view all the answers

What stimulates the synthesis of major digestive enzymes in the pancreas?

<p>Cholecystokinin (CCK) (D)</p> Signup and view all the answers

What is produced in the liver that aids in lipid metabolism?

<p>Bile (D)</p> Signup and view all the answers

What are the primary cells of the nervous system responsible for transmitting impulses?

<p>Neurons (C)</p> Signup and view all the answers

Which term describes the process that allows impulse transmission to skip from node to node?

<p>Saltatory conduction (A)</p> Signup and view all the answers

Which statement accurately describes the role of dendrites?

<p>They carry impulses toward the cell body. (B)</p> Signup and view all the answers

Which type of nerve fibers is responsible for carrying sensory information toward the central nervous system?

<p>Afferent fibers (B)</p> Signup and view all the answers

What is the primary function of myelination in nerve fibers?

<p>To facilitate rapid saltatory conduction. (C)</p> Signup and view all the answers

What is the primary purpose of the dorsal column tracts?

<p>To relay highly localized sensations to the brain (D)</p> Signup and view all the answers

What happens immediately when spinothalamic tracts transmit sensory information?

<p>They cross over immediately to the opposite side (C)</p> Signup and view all the answers

What results from damage to lower motor neurons (LMN) of a muscle?

<p>Flaccid paralysis of that muscle (C)</p> Signup and view all the answers

Which structures primarily carry sensory information to the central nervous system?

<p>Afferent nerve fibers (B)</p> Signup and view all the answers

How is the central canal of the spinal cord connected to the surrounding structures?

<p>It is continuous with the ventricular system (C)</p> Signup and view all the answers

What is a characteristic of pyramidal tracts?

<p>They synapse with lower motor neurons in the anterior horn (A)</p> Signup and view all the answers

Which of the following best describes the function of upper motor neurons?

<p>They control many spinal reflexes (A)</p> Signup and view all the answers

What is the result of setting an intubated patient to hyperventilation?

<p>Reduced dilation of cerebral arteries and decreased pressure (B)</p> Signup and view all the answers

What is the primary role of the pylorus in the digestive system?

<p>It regulates the release of chyme. (A)</p> Signup and view all the answers

What triggers the release of secretin from the S cells in the duodenum?

<p>Low pH in the duodenum. (A)</p> Signup and view all the answers

Which enzyme primarily digests triglycerides in the digestive system?

<p>Lipase. (B)</p> Signup and view all the answers

Which function is primarily associated with gastrin in digestion?

<p>Stimulating acid secretion. (C)</p> Signup and view all the answers

What is the effect of cholecystokinin (CCK) on the gallbladder?

<p>It stimulates gallbladder contraction. (C)</p> Signup and view all the answers

Which part of the small intestine is primarily responsible for mixing chyme with digestive secretions?

<p>Duodenum. (C)</p> Signup and view all the answers

What is the significance of the Ampulla of Vater in the digestive process?

<p>It is where bile and pancreatic duct meet. (C)</p> Signup and view all the answers

What adaptive response occurs in the fundus of the stomach when food is introduced?

<p>Transitional relaxation. (C)</p> Signup and view all the answers

What is the role of the hypothalamus in the endocrine system?

<p>It links the nervous and endocrine systems and regulates body functions. (A)</p> Signup and view all the answers

Which types of hormones attach to receptors located in the cytoplasm?

<p>Steroid hormones (C)</p> Signup and view all the answers

Which hormone is released by the anterior pituitary in response to gonadotropin releasing hormone?

<p>Luteinizing hormone (LH) and Follicle-stimulating hormone (FSH) (A)</p> Signup and view all the answers

What type of receptors do water-soluble hormones typically interact with?

<p>Plasma membrane receptors (C)</p> Signup and view all the answers

Which hormone is primarily associated with stress response and is released from the adrenal cortex?

<p>Corticosteroids (B)</p> Signup and view all the answers

What is the primary mechanism of neuron damage in Alzheimer's disease?

<p>Acetylcholine deficit (D)</p> Signup and view all the answers

Which symptom is most closely associated with Guillain-Barré syndrome?

<p>Ascending muscle paralysis (B)</p> Signup and view all the answers

What pathological feature is associated with Parkinson's disease?

<p>Lewy bodies (C)</p> Signup and view all the answers

Which treatment option is commonly employed in managing Multiple Sclerosis?

<p>Plasmapheresis (B), Corticosteroids (D)</p> Signup and view all the answers

What is a common cause of cerebral edema following a traumatic brain injury?

<p>Ischemia (A)</p> Signup and view all the answers

Which of the following outcomes is most likely to occur after a TBI?

<p>Functional recovery potential (D)</p> Signup and view all the answers

What type of muscle weakness is primarily associated with myasthenia gravis?

<p>Fatigue with activity and improves with rest (B)</p> Signup and view all the answers

Which finding is characteristic of schizophrenia?

<p>Increased ventricular size (B)</p> Signup and view all the answers

What is a potential outcome of an epidural hematoma?

<p>Loss of consciousness followed by alertness (A)</p> Signup and view all the answers

Which neurotransmitter imbalance is often linked to the positive symptoms of schizophrenia?

<p>Dopamine (A)</p> Signup and view all the answers

Flashcards

Protease Enzymes

Enzymes that break down proteins into peptides and amino acids.

Amylase function

Breaks down starches into simpler sugars.

Lipase function

Breaks down triglycerides into monoglycerides and fatty acids.

Gallbladder's role

Stores and concentrates bile for later release into the small intestine.

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Chyme's role

Partially digested food from the stomach, that enters the small intestine.

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Duodenum function

First part of small intestine where chyme mixes with digestive enzymes and bile.

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Sphincter of Oddi

Controls the release of pancreatic enzymes and bile into the duodenum.

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CCK's role in digestion

Hormone that slows stomach emptying and relaxes the sphincter of Oddi to allow bile flow.

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Cholecystitis

Inflammation of the gallbladder, often due to gallstones that block bile flow.

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Acute Cholecystitis Symptom

Right upper quadrant pain radiating to the right shoulder, often after eating.

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Pancreatitis (Acute)

Inflammation of the pancreas, often due to alcohol abuse.

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Cirrhosis

Chronic liver disease causing scarring.

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Fulminant Liver Failure

Severe liver damage, 90% or more of liver cells damaged.

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Acetaminophen Toxicity

Liver damage caused by excessive acetaminophen (Tylenol).

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Portal Hypertension

Increased blood pressure in the portal vein, leading to complications.

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Ascites

Fluid buildup in the abdomen, often part of liver disease (cirrhosis).

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Gynecomastia

Development of breast tissue in males, linked to liver disorders.

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NG Tube

Nasogastric tube used to decompress the stomach.

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Hyperventilation for ICP

Increasing respiratory rate to blow off CO2, reducing cerebral artery dilation and intracranial pressure. Short-term solution, limits blood flow.

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Non-Contrast CT for ICP

Imaging to assess brain structure without contrast dye. Used to monitor for swelling and expansion in patients with increased intracranial pressure.

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Repeat CT scans for ICP

Multiple CT scans are performed over time to track changes in brain swelling and expansion in cases of elevated intracranial pressure.

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CTA for ICP

CT angiography, imaging the blood vessels in the brain to look for any blockages or abnormalities contributing to increased intracranial pressure.

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Spinal Cord Size

About the diameter of a human finger.

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CSF Function for Spinal Cord

Cerebrospinal fluid cushions the spinal cord within the bony vertebrae.

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Ascending Sensory Pathways

Nerve fibers carrying sensory information from the peripheral nervous system (PNS) to the brain for interpretation.

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Descending Motor Pathways

Nerve fibers carrying motor commands from the brain to muscles for movement, originating in the precentral gyrus.

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Upper Motor Neuron Damage

Results in spastic paralysis where reflexes function but lack higher brain control.

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Enteric Nervous System

A network of neurons in the GI tract that controls digestion.

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Sympathetic Nervous System

Prepares the body for 'fight or flight' responses during stress.

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Parasympathetic Nervous System

Controls the body's 'rest and digest' functions.

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Alpha 1 Receptor

Causes vasoconstriction, increased blood pressure, and pupil dilation.

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Beta 1 Receptor

Increases heart rate, contractility, and renin release.

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Beta 2 Receptor

Causes vasodilation, bronchodilation, and glycogen breakdown.

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Norepinephrine and Epinephrine

Norepinephrine primarily stimulates alpha 1, beta 1, and beta 2 receptors, while epinephrine strongly stimulates all four receptor types.

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What is awareness?

The subjective experience of perceiving something, like a blue triangle or a red square. It also includes the ability to follow commands.

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What is arousal?

The overall state of alertness or wakefulness. It's indicated by things like opening your eyes.

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What are structural alterations?

Changes in the physical structure of the brain, such as tumors, injuries, or infections. These can affect consciousness.

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What are metabolic alterations?

Changes in the chemical environment of the brain, such as imbalances in electrolytes or blood sugar.

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What are psychogenic alterations?

People who are physiologically awake but appear unconscious. This is often caused by psychiatric disorders like catatonia.

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First messengers

Hormones that initiate a cellular response by binding to receptors on the cell surface or inside the cell.

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Water-soluble hormones

Hormones that dissolve in the bloodstream and bind to receptors on the cell membrane.

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Lipid-soluble hormones

Hormones that can pass through the cell membrane and bind to receptors inside the cell.

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Hypothalamus

The control center of the endocrine system, linking the nervous and endocrine systems and regulating many bodily functions.

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Pituitary gland

The 'master gland', attached to the hypothalamus, that releases hormones that control other endocrine glands.

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Liver's role in digestion

The liver produces bile, which helps digest fats in the small intestine. It also metabolizes nutrients absorbed from the small intestine, preparing them for use by the body.

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Pancreas's role in digestion

The pancreas secretes digestive enzymes, such as amylase, lipase, and protease, into the small intestine to break down carbohydrates, fats, and proteins.

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What is the purpose of deamination and transamination?

Deamination removes amino groups from amino acids, while transamination transfers amino groups to other molecules. These processes are integral to protein metabolism and the production of energy.

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What is the portal vein's role?

The portal vein carries nutrient-rich blood from the small intestine directly to the liver for processing before it enters the general circulation.

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What are Kupffer cells?

Kupffer cells are specialized macrophages found in the liver, acting as the liver's immune system to help clear out bacteria, toxins, and debris.

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Neurons

The primary cells of the nervous system, responsible for transmitting information.

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Neuroglial Cells

Supporting cells in the nervous system that provide structure, nutrition, and protection to neurons.

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Nerve Fiber - Dendrites

Extensions of the cell body that carry impulses towards the cell body, translating chemical messages into electrical events.

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Nerve Fiber - Axons

Long conductive projections from cell bodies that carry impulses away from the cell body. Electrical messages are transmitted from dendrite to cell body to axon hillock, where an action potential originates.

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Trypsin and Chymotrypsin

Enzymes that break down proteins into smaller peptides and amino acids.

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Chyme

Partially digested food that passes from the stomach to the small intestine.

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Spinal Cord Diameter

The spinal cord is approximately the diameter of a human finger.

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CSF's Role in the Spinal Cord

Cerebrospinal fluid (CSF) surrounds the spinal cord, cushioning it from the bony vertebrae.

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Damage to Lower Motor Neurons

Damage to lower motor neurons innervating a muscle results in flaccid paralysis of that muscle.

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Hypothalamus' role in endocrine system

The hypothalamus is the control center of the endocrine system, linking the nervous and endocrine systems and regulating many bodily functions, including temperature, appetite, sleep-wake cycles, and stress response.

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Alzheimer's Hallmarks

The key features of Alzheimer's disease are the presence of beta-amyloid plaques outside neurons, and tau-protein tangles inside neurons, both leading to neuron death and brain atrophy.

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Alzheimer's Impact

Alzheimer's causes damage to brain areas responsible for memory and thinking, such as the cortex and hippocampus, leading to shrinkage of these regions and enlargement of fluid-filled spaces (ventricles).

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Parkinson's Cause

Parkinson's results from the death of dopamine-producing neurons in the substantia nigra, a brain area involved in smooth movement control. This leads to the loss of dopamine, a neurotransmitter necessary for coordinated movements.

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Multiple Sclerosis (MS) Cause

Multiple Sclerosis is an autoimmune disease where the immune system attacks and damages the protective myelin sheath around nerve fibers in the central nervous system (CNS).

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Guillain-Barré Syndrome

An autoimmune disorder that affects the peripheral nervous system (PNS) causing inflammation and damage to the myelin sheath of nerves. It often follows a viral or bacterial infection.

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Myasthenia Gravis

An autoimmune disease that weakens muscles by targeting acetylcholine receptors at neuromuscular junctions, preventing proper nerve impulses from reaching muscles.

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Schizophrenia: Positive Symptoms

Positive symptoms in schizophrenia, like psychosis and catatonia, are linked to increased dopamine release in brain areas like the ventral tegmental area and nucleus accumbens.

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Schizophrenia: Negative Symptoms

Negative symptoms in schizophrenia, like blunted affect, are associated with reduced dopamine release in the prefrontal cortex, an area involved in emotions and thoughts.

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Brain Injury: Contralateral Effects

Damage to one side of the brain typically affects the opposite side of the body. This is because nerve pathways cross over in the brain.

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Brain Injury: Secondary Damage

Brain injuries can lead to secondary damage, such as swelling and increased pressure inside the skull (increased intracranial pressure, ICP), further damaging brain tissue.

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Study Notes

GI System

  • Four major functions: Digestion, nutrient absorption, hormone secretion, and defense against pathogens (microbiome). Structural or neurological abnormalities can hinder movement, leading to local and systemic symptoms.

Accessory Organs: Liver

  • Processes nutrients absorbed in the small intestine, transporting them to the liver via the portal vein for processing and release into the systemic circulation.
  • Deamination/Transamination (metabolism) is a key function.
  • Synthesizes proteins like albumin and clotting factors.
  • Produces bile, which is transported to the duodenum for lipid metabolism. Produces lipids, phospholipids, and cholesterol.
  • Kupffer cells are specialized macrophages.

Accessory Organs: Pancreas

  • Synthesizes and stores digestive enzymes within pancreatic acini.
  • Digestive enzymes, including trypsin and chymotrypsin (protein digestion) and amylase (starch digestion), are released in response to CCK. Problems with CCK affect enzyme release.
  • Pancreatic lipase aids in the digestion of triglycerides into monoglycerides and fatty acids for absorption.
  • Insulin and glucagon are also produced.

Accessory Organs: Gallbladder

  • Stores and concentrates bile.

Stomach

  • Secretes acid and enzymes (e.g., pepsin) to kill bacteria and begin digestion.
  • Stores food (bolus) and initiates digestion.
  • Mixes chyme.

Small Intestine: Duodenum

  • Mixes chyme with bicarbonate, mucus, and lipases.
  • Contains the ampulla of Vater, where pancreatic and hepatic bile duct entrance allows digestive enzymes into the duodenum.
  • Contains the sphincter of Oddi, which regulates the release of enzymes from the ampulla of Vater.
  • Contains specialized cells (S cells) that produce the hormone motilin.

Small Intestine: Jejunum

  • Primarily responsible for nutrient absorption.
  • Bile salts and pancreatic enzymes aid in the completion of digestion.
  • Contains enterocytes with microvilli, goblet cells for protection and lubrication.

Small Intestine: Ileum

  • Absorbs nutrients and waste products into the large intestine.
  • Contains the ileocecal valve.

Colon

  • Stores and moves stool/feces.
  • Reabsorbs water.
  • Expels stool from the body

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