Podcast
Questions and Answers
What is the main function of centrocytes in the germinal center?
What is the main function of centrocytes in the germinal center?
- Undergo somatic hypermutation
- Compete for antigen binding strength (correct)
- Produce antigens
- Proliferate rapidly
Which chemokine is produced by stromal cells in the dark zone of the germinal center?
Which chemokine is produced by stromal cells in the dark zone of the germinal center?
- CXCR4
- CXCR5
- CXCL13
- CXCL12 (correct)
What is the role of follicular dendritic cells (FDCs) in the germinal center?
What is the role of follicular dendritic cells (FDCs) in the germinal center?
- Retain centrocytes (correct)
- Produce antibodies
- Produce chemokine CXCL13
- Attract CD4 T cells
Which cell type is mainly responsible for antigen capture in B cells?
Which cell type is mainly responsible for antigen capture in B cells?
What facilitates the activation of B cells in response to protein antigens?
What facilitates the activation of B cells in response to protein antigens?
What occurs in the dark zone of the germinal center?
What occurs in the dark zone of the germinal center?
What is the main function of TFH cells in the immune response?
What is the main function of TFH cells in the immune response?
Which marker is used for identifying proliferating cells in a germinal center?
Which marker is used for identifying proliferating cells in a germinal center?
'Somatic hypermutation' primarily occurs in which area of the germinal center?
'Somatic hypermutation' primarily occurs in which area of the germinal center?
What is the role of CXCR5 in relation to germinal centers?
What is the role of CXCR5 in relation to germinal centers?
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