BIOL3120 Immunobiology Lecture 3: Innate Immunity Components Quiz

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What are the two types of lymphocytes in the lymphoid lineage?

B cells and T cells (correct)

Natural Killer cells and T cells

Macrophages and B cells

T cells and Dendritic cells

What is the definition of effector lymphocytes?

Lymphocytes that cannot mediate the removal of pathogens

Fully functional lymphocytes that differentiate from naïve lymphocytes after activation by antigen (correct)

Lymphocytes that have never encountered their specific antigens

Lymphocytes that are mature but have never undergone normal development

What are the key steps of the cellular defense of innate immunity?

Recognition, Response, Memory

Activation, Differentiation, Proliferation

Recognition, Activation, Antigen presentation (correct)

Immune memory, Specific response, Humoral response

What are hematopoietic stem cells in the bone marrow?

Stem cells responsible for producing blood cells Signup and view all the answers

What do naïve lymphocytes refer to?

Lymphocytes with no specific antigens Signup and view all the answers

Which type of immunity involves lymphocytes that have undergone normal development in the bone marrow and thymus?

Adaptive immunity Signup and view all the answers

Where does B cell development primarily occur?

Bone marrow Signup and view all the answers

What is the primary effector function of CD8+ cytotoxic T cells?

Intracellular infection by viruses Signup and view all the answers

Which recognition protein do B cells express against antigens?

Immunoglobulin (Ig) Signup and view all the answers

What is the location of the thymus in the human body?

Upper chest beneath the breastbone Signup and view all the answers

Which type of immunity involves lymphocytes that have undergone normal development in the bone marrow and thymus?

Adaptive immunity Signup and view all the answers

What is the function of secondary (peripheral) lymphoid organs?

Initiate adaptive immune response Signup and view all the answers

What is the primary function of effector lymphocytes?

"Attacking" pathogens or infected cells Signup and view all the answers

Which cells are more sensitive to antigens than naïve lymphocytes?

"Memory" lymphocytes Signup and view all the answers

What does TCR stand for in T cells?

"T Cell Receptor" Signup and view all the answers

"Immunoglobulin (Ig)" and "antibody" are used interchangeably. What is the other form of Ig besides the secreted form?

"Membrane-bound" form Signup and view all the answers

What are the effector functions of B lymphocytes?

Secretion of antibody to bind pathogens or their toxins in the extracellular space of the body Signup and view all the answers

What is the primary effector function of CD4+ helper T cells?

B cell and macrophage activation Signup and view all the answers

Where is the location of the thymus in the human body?

Upper chest beneath the breastbone Signup and view all the answers

What is the function of secondary (peripheral) lymphoid organs?

Initiate adaptive immune response Signup and view all the answers

What is the primary effector function of CD8+ cytotoxic T cells?

Intracellular infection by viruses Signup and view all the answers

Which recognition protein do B cells express against antigens?

Immunoglobulin (Ig) Signup and view all the answers

What are the two types of lymphocytes in the lymphoid lineage?

B lymphocytes (B cells) and T lymphocytes (T cells) Signup and view all the answers

What does TCR stand for in T cells?

T cell receptor Signup and view all the answers

What are memory lymphocytes more sensitive to than naïve lymphocytes?

Antigens Signup and view all the answers

What is the primary location of B cell development?

Bone marrow Signup and view all the answers

What are the primary effector cells of the adaptive immune system?

B lymphocytes (B cells) and T lymphocytes (T cells) Signup and view all the answers

Define effector lymphocytes and differentiate them from naïve lymphocytes.

Effector lymphocytes are fully functional lymphocytes that differentiate from naïve lymphocytes after activation by antigen, and can mediate the removal of pathogens without further differentiation. Naïve lymphocytes are mature but have never encountered their specific antigens. Signup and view all the answers

Explain the significance of the term 'naïve lymphocytes' in the context of the immune system.

Naïve lymphocytes are mature lymphocytes that have undergone normal development in the bone marrow and thymus but have never encountered their specific antigens. Signup and view all the answers

What is the primary function of effector lymphocytes in the immune response?

The primary function of effector lymphocytes is to mediate the removal of pathogens without further differentiation after activation by antigen. Signup and view all the answers

Explain the role of hematopoietic stem cells in the bone marrow in the context of the immune system.

Hematopoietic stem cells in the bone marrow give rise to all blood cells, including immune cells, and are crucial for the continuous generation of immune cells. Signup and view all the answers

What are the key steps of the cellular defense of innate immunity?

The key steps of the cellular defense of innate immunity include recognition of pathogens, activation of immune cells, and initiation of an inflammatory response. Signup and view all the answers