Podcast
Questions and Answers
What is the focus of pharmacogenomics?
What is the focus of pharmacogenomics?
- Regulation of miRNA-encoding genes
- Genotyping chip precision
- Influence of genetic variation on drug response (correct)
- The study of rare variants
Which type of diseases are associated with single gene disorders?
Which type of diseases are associated with single gene disorders?
- Complex multifactorial diseases
- Hypercholesterolemia
- Cystic fibrosis (correct)
- Diabetes
What is the potential problem with some GWAS findings?
What is the potential problem with some GWAS findings?
- They lack statistical power
- They are unable to identify rare variants
- They do not explain heritability (correct)
- They focus solely on single gene disorders
What is the main difference between pharmacogenomics and pharmacogenetics?
What is the main difference between pharmacogenomics and pharmacogenetics?
What is the role of SNPs in altering drug efficacy according to the text?
What is the role of SNPs in altering drug efficacy according to the text?
In what percentage of the population do naturally occurring SNPs exist?
In what percentage of the population do naturally occurring SNPs exist?
Which study type is used to explore the missing heritability in genetic studies?
Which study type is used to explore the missing heritability in genetic studies?
What is the focus of genome-wide association studies (GWAS)?
What is the focus of genome-wide association studies (GWAS)?
What do rare variants refer to in the context of genetic studies?
What do rare variants refer to in the context of genetic studies?
What is the role of epigenetic effects in heredity according to the text?
What is the role of epigenetic effects in heredity according to the text?
What does GWAS stand for in genetic research?
What does GWAS stand for in genetic research?
Which branch of pharmacology aims to predict personalized treatment based on genome sequence/expression profile?
Which branch of pharmacology aims to predict personalized treatment based on genome sequence/expression profile?
Which enzyme is responsible for metabolizing most clinically important drugs?
Which enzyme is responsible for metabolizing most clinically important drugs?
What is the effect of aberrant Her-2 gene?
What is the effect of aberrant Her-2 gene?
What is the implication of personalized genomic medicine?
What is the implication of personalized genomic medicine?
What is the function of Trastuzumab (Herceptin)?
What is the function of Trastuzumab (Herceptin)?
What is the significance of SNPs in the GLCC1 gene for asthma patients?
What is the significance of SNPs in the GLCC1 gene for asthma patients?
What type of polymorphism is a single base variation?
What type of polymorphism is a single base variation?
Which type of polymorphism involves variations in regions of DNA that involve multiple copies of genes?
Which type of polymorphism involves variations in regions of DNA that involve multiple copies of genes?
What is the minimum number of STRs required for DNA fingerprinting in forensics?
What is the minimum number of STRs required for DNA fingerprinting in forensics?
What does CODIS stand for in DNA forensics?
What does CODIS stand for in DNA forensics?
What type of genetic marker is inherited from father to son?
What type of genetic marker is inherited from father to son?
What factor may not be included in consumer genetics reports when assessing disease risk?
What factor may not be included in consumer genetics reports when assessing disease risk?
What effect does TPMT activity have on the drug 6-MP for acute lymphoblastic leukemia?
What effect does TPMT activity have on the drug 6-MP for acute lymphoblastic leukemia?
