Genetics: X-linked Inheritance & Pedigree Charts
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Questions and Answers

In a cross between a hemophilic man ($X^hY$) and a healthy woman ($X^HX^H$), what percentage of their female offspring will be carriers of the hemophilia allele?

  • 100% (correct)
  • 50%
  • 25%
  • 0%

If a healthy male ($X^HY$) has children with a healthy female carrier ($X^HX^h$) of an X-linked condition, what is the probability that their son will inherit the X-linked condition?

  • 50% (correct)
  • 25%
  • 100%
  • 0%

In a cross between a woman with red-green color blindness ($X^cX^c$) and a man with normal vision ($X^CY$), what proportion of their offspring will be color-blind?

  • 50% of offspring regardless of sex
  • All daughters and no sons
  • All sons and no daughters
  • All offspring (correct)

A woman with type A blood ($I^AI^A$) has a child with a man with type B blood ($I^BI^O$). What are the possible blood types of their offspring?

<p>AB only (C)</p> Signup and view all the answers

If a homozygous individual with blood group A ($I^AI^A$) has children with a homozygous individual with blood group B ($I^BI^B$), what blood types are possible in their offspring?

<p>AB only (C)</p> Signup and view all the answers

In a pedigree analysis, what does a filled-in square typically represent?

<p>An affected male (A)</p> Signup and view all the answers

In pedigree analysis, how can you differentiate between an individual who is homozygous dominant and one who is heterozygous for a particular trait if they both display the dominant phenotype?

<p>By examining the genotypes of their parents and offspring (C)</p> Signup and view all the answers

Which of the following best describes phenotypic variation?

<p>Differences in the observable characteristics of individuals of the same species. (A)</p> Signup and view all the answers

Height in humans is an example of continuous variation. What statistical distribution is typically observed when plotting the heights of a large population?

<p>Normal distribution (D)</p> Signup and view all the answers

Which of the following is an example of continuous variation?

<p>Hair color in humans (A)</p> Signup and view all the answers

Flashcards

Genetic Diagram

A chart that shows the possible genotypes and phenotypes of offspring from a genetic cross.

X-linked Condition

A condition caused by a recessive allele on the X chromosome; more common in males.

Codominance

When both alleles for a trait are equally expressed in a heterozygote.

Pedigree

A chart showing the inheritance of a trait in a family.

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Variations

Differences among individuals of the same biological species.

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Phenotypic Variations

Observable differences in characteristics among individuals.

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Genetic Variations

Differences in the genetic makeup of individuals.

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Continuous Variation

Variation where traits can take on a continuous range of values.

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Normal Distribution Curve

A graph showing the normal distribution of a trait.

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Continuous Trait

Occurs when observable variations are distributed along a continuous range between two extremes with no distinct categories.

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Study Notes

  • A genetic diagram illustrates X-linked inheritance through a cross between a hemophilic man and a healthy woman.
  • In a cross between a homozygous female with type A blood and a heterozygous male with type B blood, the female will pass the IA allele to offspring with a probability of 1.
  • The heterozygous male will pass the IB allele to offspring with a probability of 0.5 and the I0 allele with a probability of 0.5.
  • The probability of offspring having the IAIB genotype is 0.5 and the probability of offspring having the IAIO genotype is 0.5.
  • The phenotypic ratio of offspring with type AB blood to offspring with type A blood is 1:1.

Pedigree Charts

  • Pedigrees display inheritance patterns across multiple generations, showing the ancestral history of related individuals.
  • Pedigrees are family trees arranged with the oldest generation at the top and the youngest at the bottom.
  • Circles represent females, and squares represent males in a pedigree.
  • Shaded shapes indicate individuals expressing a specific genetic trait.
  • A horizontal line connects parents, and a vertical line extends to their children.
  • Generations in a pedigree are numbered with Roman numerals, and individuals within each generation are numbered with Arabic numerals.
  • Figure 11.13 shows a pedigree for fur color inheritance; grey shapes denote black fur, and a white circle indicates white fur.

Population Variations

  • Variations are differences between individuals of the same species.
  • Phenotypic variations are differences in observable characteristics.
  • Genetic variations are differences in the genotypes of individuals.
  • Continuous variation occurs when variations span a continuous range between two extremes, without distinct categories.
  • Continuous variation produces a range of phenotypes, not a set number.
  • Height and weight demonstrate continuous variation.
  • The height of an individual can fall within a range of possible values or phenotypes.
  • Plotting heights in a population typically forms a normal distribution curve.
  • A normal distribution curve indicates that most individuals are near the average height, with fewer at extreme heights.
  • Weight and other traits that show continuous variation also form a normal distribution curve when graphed.

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Description

Explore X-linked inheritance using genetic diagrams, including a hemophilic man and healthy woman scenario. Understand blood type inheritance probabilities. Learn how pedigree charts display inheritance patterns across generations, including symbols for males, females, and affected individuals.

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