Genetics: Substitution Mutations
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Questions and Answers

What is a silent mutation?

  • A mutation that occurs only in the first base of a codon.
  • A mutation that causes a different amino acid to be produced.
  • A mutation that changes a nucleotide but does not alter the amino acid sequence. (correct)
  • A mutation that results in a premature stop codon.

Which part of the codon is least likely to change in a silent mutation?

  • The first base (correct)
  • The second base
  • The third base
  • None of the above

How many different triplet codon sequences can code for the amino acid valine?

  • Three
  • Two
  • Four (correct)
  • Five

What is the main characteristic of a substitution mutation?

<p>It replaces one nucleotide with another. (A)</p> Signup and view all the answers

In which scenario would a silent mutation most likely occur?

<p>In the second or third position, retaining the same amino acid. (A)</p> Signup and view all the answers

Flashcards

Silent Mutation

A type of mutation where one nucleotide is replaced with another, but the resulting amino acid remains the same.

Codon

A group of three nucleotides that codes for a specific amino acid.

Translation

The process of converting a sequence of DNA nucleotides into a sequence of amino acids.

Mutation

Any change in the nucleotide sequence of DNA.

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Amino Acid

The building blocks of proteins, each with a specific structure and function.

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Study Notes

Substitution Mutations

  • Substitution mutations involve replacing one nucleotide with another.
  • Silent mutations are a type of neutral mutation.
  • A silent mutation changes the nucleotide sequence but not the amino acid sequence.
  • This is possible because some amino acids have multiple codon sequences.
  • Silent mutations often affect the second or third base of a codon.

Codon Example (Valine)

  • The amino acid valine is coded for by four codons: GUU, GUC, GUA, and GUG.
  • The first two nucleotides (GU) determine the amino acid is valine.
  • Changing the third nucleotide (U to C, A, or G) still codes for valine.

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Description

Explore the fascinating world of substitution mutations in genetics. This quiz delves into silent mutations and their impact on codon sequences, specifically focusing on valine and its multiple codons. Test your knowledge on how nucleotide changes can affect amino acid coding.

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