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Questions and Answers
What is the primary function of oncogenes in the context of cancer development?
What is the primary function of oncogenes in the context of cancer development?
How do tumor-suppressor genes contribute to preventing cancer development?
How do tumor-suppressor genes contribute to preventing cancer development?
Which gene is commonly associated with retinoblastoma, a tumor of the retina?
Which gene is commonly associated with retinoblastoma, a tumor of the retina?
What happens when tumor-suppressor genes are inactivated by mutation?
What happens when tumor-suppressor genes are inactivated by mutation?
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In individuals with inherited retinoblastoma, when does the disease typically occur?
In individuals with inherited retinoblastoma, when does the disease typically occur?
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What type of genes are proto-oncogenes before they undergo mutation?
What type of genes are proto-oncogenes before they undergo mutation?
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Which gene facilitates apoptosis by promoting programmed cell death?
Which gene facilitates apoptosis by promoting programmed cell death?
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What is the main effect of tumor-suppressor genes when functioning normally?
What is the main effect of tumor-suppressor genes when functioning normally?
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Which proteins fall into the category of maintaining genome integrity as tumor-suppressor genes?
Which proteins fall into the category of maintaining genome integrity as tumor-suppressor genes?
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What happens to tumor-suppressor genes when they lose their ability to inhibit cancer?
What happens to tumor-suppressor genes when they lose their ability to inhibit cancer?
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Which proteins control the cell cycle by regulating the G1-to-S transition?
Which proteins control the cell cycle by regulating the G1-to-S transition?
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What is the main role of the spindle assembly checkpoint in the cell cycle?
What is the main role of the spindle assembly checkpoint in the cell cycle?
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What is the predisposition for developing cancer often a result of?
What is the predisposition for developing cancer often a result of?
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Which term describes the phenomenon where cancer results from the loss of the normal copy of a gene?
Which term describes the phenomenon where cancer results from the loss of the normal copy of a gene?
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Which gene is NOT listed among the examples of tumor-suppressor genes in the text?
Which gene is NOT listed among the examples of tumor-suppressor genes in the text?
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Inherited forms of cancer most commonly involve defects in which type of genes?
Inherited forms of cancer most commonly involve defects in which type of genes?
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What does LOH stand for in the context of cancer development?
What does LOH stand for in the context of cancer development?
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Which of the following is NOT mentioned as an example of a tumor-suppressor gene in the text?
Which of the following is NOT mentioned as an example of a tumor-suppressor gene in the text?
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