Genetics, Immunity, and Cancer Quiz

8 Questions

What is the cause of severe combined immune deficiency (SCID)?

Lack of T cells and B cells

What is the role of the FLG gene in the immune system?

None of the above

Which virus is NOT linked to cancer?

HCV

What is the aim of the Gardasil 9 Vaccine?

Protect against 9 strains of HPV virus

What is the cause of Epidermodysplasia verruciformis?

Inherited mutation on two genes on chromosome 17

What is autoimmunity?

When the immune system attacks the body's own tissues

What is the role of driver mutations in cancer?

Provide the selective growth advantage to a cell that defines the cancerous state

What are potential contributing factors in cancer?

Inherited mutations, environmental exposures, toxic substances, UV radiation, and viral exposure

Study Notes

Karyotypes can show chromosomal abnormalities.
Blood type can influence an immune response.
Rh incompatibility can cause infant mortality rates to decline.
The immune system has innate and adaptive immunity.
Severe combined immune deficiency (SCID) is a disorder with no T cells or B cells.
Allergies are immune system responses to non-threatening substances.
Mutations in the FLG gene can cause atopic dermatitis, peanut allergies, asthma, and hay fever.
Autoimmunity occurs when the immune system attacks the body's own tissues.
APECED is a rare genetic disorder characterized by autoimmune problems.
Skewed X inactivation may explain why some autoimmune disorders are more common in females.
Mutations in BRCA2 gene increase risk of breast, ovarian, prostate, and other cancers.
BRCA2 is a gene on chromosome 13.
7 viruses are linked to cancer, including HPV, EBV, HBV, HCV, HIV, HHV-8, and HTLV-1.
Merkel cell polyomavirus is also linked to cancer.
Epstein-Barr virus can cause MYC gene mutation.
MYC regulates cell division.
Retroviruses can cause cancer.
Human papillomavirus is a sexually transmitted virus linked to cervical cancer.
Certain mutations in BRCA2 gene increase risk of cancer.
Epstein-Barr virus can lead to MYC gene mutation.
Gardasil 9 Vaccine can protect against 9 strains of HPV virus.
The aim is to identify factors that can lead to the development of cancer.
Ways to protect oneself against cancers caused by viruses are discussed.
The man in the text has Epidermodysplasia verruciformis caused by a mutation on two genes on chromosome 17.
Driver mutations provide the selective growth advantage to a cell that defines the cancerous state.
Cancers can be caused by inherited mutations, environmental exposures, toxic substances, UV radiation, and viral exposure.
Groups of three are tasked with creating a claim regarding whether vaping increases the risk of lung cancer.
The text discusses genetics and disease, including abnormal karyotypes, human syndromes, immune system disorders, and genetic changes in cancer cells.
Inherited susceptibility and sporadic cancers are distinguished.
Potential contributing factors in cancer, such as colon and lung cancer, are named and described.