Genetics and Epigenetics Quiz
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Questions and Answers

What do the concordance rates of 75% for MZ twins and 30% for DZ twins suggest about the disease?

  • The disease is viral in nature.
  • The disease is only affected by environmental factors.
  • There is a genetic component. (correct)
  • The disease has been histone modified.

Which structure is responsible for utilizing RNA to synthesize proteins?

  • Endoplasmic reticulum.
  • Mitochondria.
  • Ribosome. (correct)
  • Lysosome.

What is sperm protamine interaction with DNA primarily an example of?

  • Genomic imprinting.
  • Chromatin remodeling.
  • Transcriptional activation.
  • Epigenetics. (correct)

Which of the following is an example of a phenotype?

<p>Hair color. (D)</p> Signup and view all the answers

What primarily determines a cell's size?

<p>Amount of cytosol. (C)</p> Signup and view all the answers

In which part of the cell is DNA predominantly stored?

<p>Nucleus. (A)</p> Signup and view all the answers

What factor is necessary for genetic mutations to occur?

<p>Chance. (D)</p> Signup and view all the answers

Which of the following is an RNA nitrogenous base but not found in DNA?

<p>Uracil. (D)</p> Signup and view all the answers

Flashcards

MZ vs DZ concordance

Identical twins share more genetic similarity than fraternal twins, so the higher concordance rate for MZ twins compared to DZ twins points to a genetic influence on the disease.

Protein synthesis

The process by which genetic information is translated into proteins using messenger RNA (mRNA).

Epigenetics

The study of heritable changes that affect gene expression without altering the underlying DNA sequence. It includes mechanisms like DNA methylation and histone modification.

Phenotype

Observable characteristics or traits of an organism. It can be anything from physical characteristics like hair color to complex traits like susceptibility to a disease. It is the result of the interaction between genotype and environment.

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Nucleus

The storage center of the cell's genetic material (DNA) in the form of chromosomes. It is responsible for regulating gene expression and ensuring accurate DNA replication.

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Proofreading in DNA replication

The process by which DNA polymerase checks its work during DNA replication and corrects any mismatched nucleotides. It helps maintain the accuracy of DNA replication.

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Genetic mutation

A change in the DNA sequence that can be inherited. It can be caused by various factors such as radiation, chemical exposure, or errors during DNA replication.

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Uracil (U)

A nitrogenous base found in RNA but not in DNA. It pairs with adenine (A) during transcription.

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Study Notes

Concordance Rates and Disease

  • A concordance rate of 75% for MZ twins and 30% for DZ twins indicates a significant genetic component to the disease.

Protein Synthesis

  • Ribosomes use RNA to synthesize proteins.

Epigenetics Examples

  • Sperm protamine interaction with DNA is an example of epigenetics.

Phenotype Example

  • Hair color is an example of a phenotype.

Cell Size Determination

  • Cell size is NOT determined by the amount of cytosol, DNA in the nucleus, or translation of DNA.

DNA Location

  • DNA is stored in the nucleus of a cell.

Genetic Mutation Triggers

  • Genetic mutations occur due to chance.

RNA vs DNA Bases

  • Uracil is an RNA nitrogenous base, but not a DNA base.

DNA Repair During Replication

  • Proofreading is a process that repairs DNA strands during replication.

Heritable vs. Non-Heritable Mutations

  • Mutations in somatic cells are not passed down to offspring.

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Description

Test your knowledge on key concepts in genetics, including concordance rates, protein synthesis, and mutations. Explore examples of epigenetics and understand the differences between heritable and non-heritable mutations. This quiz covers essential topics related to DNA and cell biology.

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