10 Questions
What is a mutation?
A change in the nucleotide sequence of a DNA molecule
Which type of mutations can be inherited by offspring?
Germline mutations
What are the principal causes of many diseases like cancer?
Somatic mutations
In what way can mutations arise from the action of mutagens?
By breaking polynucleotide strands
What is the most frequent spontaneous mutation?
Depurination of guanine
How can chemical mutagens contribute to mutation?
By incorporating mismatched bases during replication
Which type of mutation causes the substitution of an incorrect amino acid?
Nonsense mutation
What is the effect of a nonsense mutation?
The codon becomes a termination codon
Which source is categorized as an endogenous source (Internal) of induced mutations?
Reactive oxygen species
What is the result of deamination during a spontaneous mutation?
Conversion of cytosine to uracil
Test your understanding of genetic variation and DNA repair mechanisms with this quiz. Explore the concept of mutations and their impact on DNA sequences, particularly in relation to diseases such as cancer.
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