Genetic Skin Disorder Manifestations

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5 Questions

What is the estimated prevalence of carriers of the condition in the population?

Two to four per thousand persons

When do the dermatologic manifestations typically become clinically evident?

In the first 3 years of life

Which area is commonly affected by diffuse transgredient palmar-plantar keratosis?

Palms and soles

What is a typical presentation of the dermatologic manifestations?

White, light-yellow, brown, or red plaques and patches

What oral manifestations are seen in patients with the condition?

Gingivitis and periodontitis

Test your knowledge on the clinical manifestations of a genetic skin disorder that manifests in early childhood, causing symptoms such as palmar-plantar keratosis, nail dystrophy, hyperhidrosis, and follicular hyperkeratosis. Learn about the prevalence and carriers of this rare condition.

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