Genetic Code and Codon Properties
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Questions and Answers

What happens when a single base pair insertion occurs in an mRNA sequence?

  • It terminates translation.
  • It deletes the codon.
  • It alters the reading frame. (correct)
  • It duplicates the codon.
  • Which amino acid has the most number of codons specifying it?

  • Leucine (correct)
  • Tryptophan
  • Methionine
  • Isoleucine
  • How many of the 64 possible codons signal chain termination?

  • 3 (correct)
  • 2
  • 4
  • 1
  • In what orientation do mRNA codons pair with tRNA anticodons?

    <p>Antiparallel</p> Signup and view all the answers

    What is the main reason for redundancy in the genetic code?

    <p>Amino acids can be specified by multiple codons.</p> Signup and view all the answers

    Which of the following is true about the genetic code?

    <p>It is nearly universal and non-overlapping.</p> Signup and view all the answers

    What are the three main stages of bacterial protein synthesis?

    <p>Initiation, Elongation, Termination</p> Signup and view all the answers

    What did Francis Crick propose in his adaptor hypothesis?

    <p>Amino acids are carried to the mRNA by an adaptor</p> Signup and view all the answers

    Which of the following is NOT a property of the genetic code?

    <p>Overlapping</p> Signup and view all the answers

    What does a non-overlapping code mean in the context of the genetic code?

    <p>Each nucleotide triplet is only read once</p> Signup and view all the answers

    How many different aminoacyl tRNA synthetases are there?

    <p>20</p> Signup and view all the answers

    What does 'degenerate' mean in relation to the genetic code?

    <p>Multiple codons can code for the same amino acid</p> Signup and view all the answers

    What role do tRNAs play in protein synthesis?

    <p>They carry amino acids to the ribosome</p> Signup and view all the answers

    What is the function of ribosomes in protein synthesis?

    <p>Translate mRNA into a chain of amino acids</p> Signup and view all the answers

    Which statement about the genetic code is correct?

    <p>It contains start and stop codons</p> Signup and view all the answers

    Which process requires a large number of tRNA molecules?

    <p>Translation</p> Signup and view all the answers

    Study Notes

    The Genetic Code

    • A single base pair insertion alters the reading frame, resulting in a different sequence of amino acids
    • The genetic code is degenerate, meaning that there is redundancy but no ambiguity

    Codon Properties

    • Codons are written in the 5'-3' direction
    • The 3rd base is less important in codon reading
    • Only Met and Trp have a single codon
    • Some codons are more abundant than others due to the availability of tRNAs

    mRNA Codons and tRNA Anticodons

    • The codon sequence is complementary to the anticodon sequence
    • The codon in mRNA base pairs with the anticodon in tRNA via hydrogen bonding
    • The alignment of two RNA segments is antiparallel

    Key Points of the Genetic Code

    • Each of the 20 amino acids in proteins is specified by one or more nucleotide triplets in mRNA
    • Of the 64 possible triplets, 61 specify amino acids and 3 signal chain termination
    • The code is non-overlapping, with each nucleotide part of a single codon
    • The genetic code is nearly universal, with the 64 triplets having the same meaning in all organisms

    Protein Synthesis

    • Protein synthesis occurs in a large macromolecular assembly called the ribosome
    • The process involves many proteins and several RNA molecules
    • It uses a large number of tRNAs that interact with mRNA
    • Each tRNA is charged with one of the 20 common amino acids by 20 different aminoacyl tRNA synthetases

    The Triplet Code

    • The genetic code is a non-overlapping code, meaning that a sequence of three nucleotides can only be read once
    • This is in contrast to an overlapping code, where a sequence of three nucleotides can be read more than once

    Antibiotics and Protein Synthesis

    • Antibiotics target ribosome sites during bacterial protein synthesis
    • The process of protein synthesis in bacteria can be divided into three stages: initiation, elongation, and termination

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    Description

    Learn about the genetic code, its properties, and how codons and tRNA anticodons work together. Understand the impact of base pair insertions and the redundancy of the genetic code.

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