Podcast
Questions and Answers
What is the primary significance of the prolonged duration of a cardiac contractile cell action potential?
What is the primary significance of the prolonged duration of a cardiac contractile cell action potential?
- Prevents tetanus and allows time for ventricular filling (correct)
- Increases heart rate significantly
- Allows rapid firing of the heart
- Enhances electrical conductivity in the heart
Which event corresponds to the QRS complex in the ECG during a single heartbeat?
Which event corresponds to the QRS complex in the ECG during a single heartbeat?
- Atrial contraction
- Atrial depolarization
- SA nodal action potential
- Ventricular contraction (correct)
During which phase of the cardiac cycle does the end-diastolic volume (EDV) occur?
During which phase of the cardiac cycle does the end-diastolic volume (EDV) occur?
- Ventricular filling (correct)
- Isovolumetric relaxation
- Isovolumetric contraction
- Ejection
What defines a septal defect in the heart?
What defines a septal defect in the heart?
What occurs during the isovolumetric relaxation phase of the cardiac cycle?
What occurs during the isovolumetric relaxation phase of the cardiac cycle?
Which of the following best describes the term 'stroke volume'?
Which of the following best describes the term 'stroke volume'?
What is indicated by a dicrotic notch in the arterial pressure waveform?
What is indicated by a dicrotic notch in the arterial pressure waveform?
Which phase follows the atrial contractile cell action potential during a heartbeat?
Which phase follows the atrial contractile cell action potential during a heartbeat?
What is the primary role of the diaphragm during quiet, resting inhalation?
What is the primary role of the diaphragm during quiet, resting inhalation?
Which muscles are involved in forced exhalation?
Which muscles are involved in forced exhalation?
How is functional residual capacity (FRC) defined?
How is functional residual capacity (FRC) defined?
What is the transmural pressure calculated as during the FRC phase?
What is the transmural pressure calculated as during the FRC phase?
At functional residual capacity (FRC), what is true about the relationship between atmospheric pressure and alveolar pressure?
At functional residual capacity (FRC), what is true about the relationship between atmospheric pressure and alveolar pressure?
What pressure is indicated by Pip at FRC?
What pressure is indicated by Pip at FRC?
During exhalation, which muscle action is performed by the rectus abdominis?
During exhalation, which muscle action is performed by the rectus abdominis?
Which condition describes the presence of air in the pleural space leading to lung collapse?
Which condition describes the presence of air in the pleural space leading to lung collapse?
What does the 1st heart sound 'lub' indicate during the cardiac cycle?
What does the 1st heart sound 'lub' indicate during the cardiac cycle?
How is stroke volume (SV) calculated?
How is stroke volume (SV) calculated?
During the isovolumetric ventricular relaxation phase, what happens to the pressure in the ventricles compared to the aorta?
During the isovolumetric ventricular relaxation phase, what happens to the pressure in the ventricles compared to the aorta?
What is the typical stroke volume at rest?
What is the typical stroke volume at rest?
What does the 2nd heart sound 'dup' signify in the cardiac cycle?
What does the 2nd heart sound 'dup' signify in the cardiac cycle?
What is stenosis in relation to heart valve defects?
What is stenosis in relation to heart valve defects?
What is a key difference between the systemic and pulmonary circulations?
What is a key difference between the systemic and pulmonary circulations?
What determines the opening and closing of all heart valves?
What determines the opening and closing of all heart valves?
What initiates the contraction of muscle fibers?
What initiates the contraction of muscle fibers?
What role do the ventricular papillary muscles play during ventricular systole?
What role do the ventricular papillary muscles play during ventricular systole?
How is blood in a typical healthy individual primarily composed?
How is blood in a typical healthy individual primarily composed?
Which statement about sickle-cell disease or trait is correct?
Which statement about sickle-cell disease or trait is correct?
Which of the following factors would decrease blood flow the most?
Which of the following factors would decrease blood flow the most?
What is the role of capillary hydrostatic pressure (Pc) in bulk flow?
What is the role of capillary hydrostatic pressure (Pc) in bulk flow?
Which of the following is NOT a Starling force that determines bulk flow?
Which of the following is NOT a Starling force that determines bulk flow?
What happens when the net filtration pressure (NFP) is negative?
What happens when the net filtration pressure (NFP) is negative?
What is the primary function of the lymphatic system in relation to bulk flow?
What is the primary function of the lymphatic system in relation to bulk flow?
Which statement about filtration and absorption is accurate?
Which statement about filtration and absorption is accurate?
What is the effect of sympathetic stimulation on the action potential upstroke in AV node cells?
What is the effect of sympathetic stimulation on the action potential upstroke in AV node cells?
How does the Frank-Starling mechanism help in balancing left and right ventricular output?
How does the Frank-Starling mechanism help in balancing left and right ventricular output?
What is the primary consequence of decreased L-type Ca2+ current due to parasympathetic stimulation?
What is the primary consequence of decreased L-type Ca2+ current due to parasympathetic stimulation?
Which term describes the resistance the heart must overcome to eject blood during contraction?
Which term describes the resistance the heart must overcome to eject blood during contraction?
In what way does the ventricular-function curve differ from the length-tension relationship in skeletal muscle?
In what way does the ventricular-function curve differ from the length-tension relationship in skeletal muscle?
What is an expected consequence of increased end-diastolic volume (EDV) on stroke volume according to the Frank-Starling mechanism?
What is an expected consequence of increased end-diastolic volume (EDV) on stroke volume according to the Frank-Starling mechanism?
What role do neurohormones primarily play in altering cardiac function?
What role do neurohormones primarily play in altering cardiac function?
What is the ejection fraction (EF)?
What is the ejection fraction (EF)?
Flashcards
Systole
Systole
Phase of the cardiac cycle where the ventricles contract, increasing pressure and causing the "lub" sound.
Ventricular Ejection
Ventricular Ejection
Phase of systole where blood is pumped out of the ventricles into the aorta and pulmonary artery.
Stroke Volume (SV)
Stroke Volume (SV)
Volume of blood pumped from each ventricle per beat.
End-Diastolic Volume (EDV)
End-Diastolic Volume (EDV)
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End-Systolic Volume (ESV)
End-Systolic Volume (ESV)
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Isovolumetric Ventricular Relaxation
Isovolumetric Ventricular Relaxation
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Wiggers Diagram
Wiggers Diagram
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Heart Valve Stenosis
Heart Valve Stenosis
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Heart Valve Insufficiency
Heart Valve Insufficiency
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Cardiac Cycle
Cardiac Cycle
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Pulmonary Circulation
Pulmonary Circulation
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Systemic Circulation
Systemic Circulation
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1st Heart Sound
1st Heart Sound
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2nd Heart Sound
2nd Heart Sound
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Cardiac Contractile Cell Action Potential Duration
Cardiac Contractile Cell Action Potential Duration
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ECG P Wave
ECG P Wave
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SA Nodal Action Potential
SA Nodal Action Potential
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Atrial Contractile Cell AP
Atrial Contractile Cell AP
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QRS Complex (ECG)
QRS Complex (ECG)
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Ventricular Contractile Cell AP
Ventricular Contractile Cell AP
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ECG T Wave
ECG T Wave
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Cardiac Cycle Phases
Cardiac Cycle Phases
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Ventricular Filling (Cardiac Cycle)
Ventricular Filling (Cardiac Cycle)
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Isovolumetric Contraction
Isovolumetric Contraction
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Ejection (Cardiac Cycle)
Ejection (Cardiac Cycle)
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Isovolumetric Relaxation
Isovolumetric Relaxation
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End-Diastolic Volume (EDV)
End-Diastolic Volume (EDV)
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End-Systolic Volume (ESV)
End-Systolic Volume (ESV)
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Sympathetic innervation effect on AV node
Sympathetic innervation effect on AV node
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Parasympathetic innervation effect on AV node
Parasympathetic innervation effect on AV node
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Frank-Starling Mechanism
Frank-Starling Mechanism
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Frank-Starling Mechanism implications
Frank-Starling Mechanism implications
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Afterload
Afterload
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Contractility
Contractility
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Ejection Fraction
Ejection Fraction
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Inotropic Effects
Inotropic Effects
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Diffusion (across conc gradients)
Diffusion (across conc gradients)
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Bulk Flow
Bulk Flow
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Filtration (bulk flow)
Filtration (bulk flow)
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Absorption (bulk flow)
Absorption (bulk flow)
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Starling forces
Starling forces
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Capillary hydrostatic pressure (Pc)
Capillary hydrostatic pressure (Pc)
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Interstitial fluid hydrostatic pressure (Pif)
Interstitial fluid hydrostatic pressure (Pif)
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Osmotic force due to ISF protein concentration (Ï€if)
Osmotic force due to ISF protein concentration (Ï€if)
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Osmotic force due to plasma protein concentration (Ï€c)
Osmotic force due to plasma protein concentration (Ï€c)
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Net Filtration Pressure (NFP)
Net Filtration Pressure (NFP)
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Lymphatic system
Lymphatic system
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ATP role in force generation
ATP role in force generation
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Desmosomes/Gap junctions
Desmosomes/Gap junctions
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Ca2+ and contraction
Ca2+ and contraction
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Negative resting membrane potential
Negative resting membrane potential
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Sliding filament model
Sliding filament model
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Ventricular papillary muscles contraction time
Ventricular papillary muscles contraction time
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Blood composition (general)
Blood composition (general)
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Sickle-cell trait/disease benefit
Sickle-cell trait/disease benefit
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Factor decreasing blood flow
Factor decreasing blood flow
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Quiet Inhalation Muscles
Quiet Inhalation Muscles
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Quiet Exhalation
Quiet Exhalation
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Forced Exhalation Muscles
Forced Exhalation Muscles
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Functional Residual Capacity (FRC)
Functional Residual Capacity (FRC)
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Transmural Pressure
Transmural Pressure
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Transpulmonary Pressure (Ptp)
Transpulmonary Pressure (Ptp)
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Chest Wall Pressure (Pcw)
Chest Wall Pressure (Pcw)
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Atmospheric Pressure (Patm)
Atmospheric Pressure (Patm)
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Alveolar Pressure (Palv)
Alveolar Pressure (Palv)
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Intrapleural Pressure (Pip)
Intrapleural Pressure (Pip)
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Pneumothorax
Pneumothorax
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Atelectasis
Atelectasis
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Study Notes
General Study Notes
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